{"id":6759,"date":"2021-12-16T06:02:51","date_gmt":"2021-12-16T11:02:51","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/dekapeptid-12-lumixyl-cas-137665-91-9-inhibuje-tvorbu-melaninu\/"},"modified":"2021-12-16T06:02:51","modified_gmt":"2021-12-16T11:02:51","slug":"dekapeptid-12-lumixyl-cas-137665-91-9-inhibuje-tvorbu-melaninu","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/dekapeptid-12-lumixyl-cas-137665-91-9-inhibuje-tvorbu-melaninu\/","title":{"rendered":"Dekapeptid-12\/Lumixyl CAS 137665-91-9 inhibuje tvorbu melaninu"},"content":{"rendered":"

Dekapeptid-12\/Lumixyl CAS 137665-91-9 inhibuje tvorbu melaninu<\/strong><\/h2>\n

N\u00e1zev produktu: Dekapeptid-12
\nSynonyma: Dekapeptid-12;Dekapeptid-12\/ Lumixyl;Dekapeptid-12 lumixyl \/ kosmetick\u00fd peptid;L-tyrosin, L-tyrosyl-L-arginyl-L-seryl-L- arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptofyl-;Dekapeptid-12 USP\/EP\/BP
\nCAS: 137665-91-9
\nMF: C65H90N18O17
\n MW: 1395.52
\nEINECS:
\nKategorie produkt\u016f:
\nMol File: 137665-91-9.mol<\/p>\n

Dekapeptid-12 je kosmetick\u00e1 surovina, kter\u00e1 inhibuje tvorbu melaninu, zesv\u011btluje pigmentaci, redukuje pigmentace a vyrovn\u00e1v\u00e1 a rozjas\u0148uje t\u00f3n pleti. Byl vyvinut v\u00fdzkumn\u00edky ze Stanford Dermatology a jako jedin\u00fd je prok\u00e1z\u00e1no, \u017ee \u00fa\u010dinn\u011b inhibuje tyrosin\u00e1zu (tyrosin\u00e1za podporuje nadm\u011brnou produkci melaninu, co\u017e m\u00e1 za n\u00e1sledek nerovnom\u011brnou pigmentaci, tmav\u00e9 skvrny atd.), co\u017e je nov\u00e1 peptidov\u00e1 aktivita. Dekapeptid-12 je oligopeptid, kter\u00fd se skl\u00e1d\u00e1 z pouh\u00fdch 12 aminokyselin. Tento oligopeptid je zn\u00e1m\u00fd svou anti-tyrosin\u00e1zovou aktivitou.<\/p>\n

Tyrosin\u00e1za se nach\u00e1z\u00ed v rostlinn\u00fdch a \u017eivo\u010di\u0161n\u00fdch tk\u00e1n\u00edch a je zodpov\u011bdn\u00e1 za katal\u00fdzu melaninu a dal\u0161\u00edch pigment\u016f. Dekapeptid-12 je zkoum\u00e1n pro jeho mo\u017enou schopnost sn\u00ed\u017eit ztmavnut\u00ed k\u016f\u017ee. Je schopen interferovat s tyrosin\u00e1zou a zesv\u011btlit k\u016f\u017ei na zv\u00ed\u0159ec\u00edch modelech. Dekapeptid-12 redukuje v\u00fdskyt hyperpigmentace \u2013 sta\u0159eck\u00fdch skvrn, slune\u010dn\u00edch skvrn, nerovnom\u011brn\u00e9ho t\u00f3nu pleti a po\u0161kozen\u00ed zp\u016fsoben\u00e9ho fotografiemi \u2013 bez typick\u00fdch vedlej\u0161\u00edch \u00fa\u010dink\u016f jin\u00fdch rozjas\u0148ova\u010d\u016f, jako je podr\u00e1\u017ed\u011bn\u00ed a zarudnut\u00ed. Nav\u00edc zklid\u0148uj\u00edc\u00ed antioxidanty, jako je ko\u0159en l\u00e9ko\u0159ice, tak\u00e9 zm\u00edr\u0148uj\u00ed citlivou poko\u017eku.<\/p>\n

Dekapeptid-12 redukuje v\u00fdskyt hyperpigmentac\u00ed \u2013 sta\u0159eck\u00fdch skvrn, slune\u010dn\u00edch skvrn, nerovnom\u011brn\u00e9ho t\u00f3nu pleti a po\u0161kozen\u00ed fotografi\u00ed \u2013 bez typick\u00fdch vedlej\u0161\u00edch \u00fa\u010dink\u016f jin\u00fdch rozjas\u0148ova\u010d\u016f, jako je podr\u00e1\u017ed\u011bn\u00ed a zarudnut\u00ed. Nav\u00edc zklid\u0148uj\u00edc\u00ed antioxidanty, jako je ko\u0159en l\u00e9ko\u0159ice, tak\u00e9 usnad\u0148uj\u00ed citlivou poko\u017eku.<\/p>\n

Fungsi<\/strong>
\n Funkce a aplikace dekapeptidu-12\/ Lumixyl CAS 137665-91-9<\/strong>
\n Dekapeptid-12 se reverzibiln\u011b v\u00e1\u017ee na tyrosin\u00e1zu, enzym nach\u00e1z\u00ed se v \u0159ad\u011b r\u016fzn\u00fdch bun\u011bk produkuj\u00edc\u00edch pigment. Zabra\u0148uje tyrosin\u00e1ze, aby katalyzovala oxidaci fenol\u016f, co\u017e je prvn\u00ed krok p\u0159i produkci melaninu. U savc\u016f se tyrosin\u00e1za nach\u00e1z\u00ed pouze v melanosomech, speci\u00e1ln\u00edch kompartmentech v bu\u0148k\u00e1ch produkuj\u00edc\u00edch pigment.
\n Tyrosin\u00e1za se u r\u016fzn\u00fdch druh\u016f nezachov\u00e1v\u00e1 a ve skute\u010dnosti se m\u016f\u017ee v\u00fdrazn\u011b li\u0161it ve struktu\u0159e dokonce i mezi bl\u00edzce p\u0159\u00edbuzn\u00fdmi druhy. U lid\u00ed ur\u010duj\u00ed rozd\u00edly v \u00fa\u010dinnosti tyrosin\u00e1zy barvu k\u016f\u017ee a jsou v\u00fdsledkem m\u00edrn\u00fdch modifikac\u00ed v genu TYR nalezen\u00e9m na chromozomu 11.
\n Dekapeptid-12 je p\u0159ibli\u017en\u011b 17kr\u00e1t \u00fa\u010dinn\u011bj\u0161\u00ed ne\u017e p\u0159edchoz\u00ed l\u00e9\u010dba hyperpigmentace, v\u010detn\u011b hydrochinonu. Studie na kultivovan\u00fdch melanocytech po dobu 7 dn\u016f prok\u00e1zaly 27%-43% sn\u00ed\u017een\u00ed obsahu melaninu.
\n Dekapeptid-12 pro\u0161el \u010detn\u00fdmi testy na zv\u00ed\u0159atech a m\u016f\u017ee b\u00fdt nakonec zahrnut do komer\u010dn\u00edch produkt\u016f pro l\u00e9\u010dbu hyperpigmentace.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: Dekapeptid-12\/ Lumixyl
\nCAS: 137665-91-9
\nMF: C65H90N18O17
\nMW: 1395,52
\nMol Soubor: 137665-91-9.mol<\/p>\n","protected":false},"featured_media":2097,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[557,557],"product_tag":[3042],"class_list":{"0":"post-6759","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-belici-peptid","8":"product_tag-decapeptide-12-lumixyl-cas-137665-91-9-inhibits-melanin-formation-cs","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/6759","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=6759"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2097"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=6759"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=6759"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=6759"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=6759"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}