{"id":7385,"date":"2021-12-16T07:57:33","date_gmt":"2021-12-16T12:57:33","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/bivalirudin-cas-128270-60-0-je-antikoagulant-pro-laboratorni-vyzkum\/"},"modified":"2021-12-16T07:57:33","modified_gmt":"2021-12-16T12:57:33","slug":"bivalirudin-cas-128270-60-0-je-antikoagulant-pro-laboratorni-vyzkum","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/bivalirudin-cas-128270-60-0-je-antikoagulant-pro-laboratorni-vyzkum\/","title":{"rendered":"Bivalirudin CAS 128270-60-0 je antikoagulant pro laboratorn\u00ed v\u00fdzkum"},"content":{"rendered":"

Bivalirudin CAS 128270-60-0 je antikoagulant pro laboratorn\u00ed v\u00fdzkum<\/strong><\/h2>\n

N\u00e1zev produktu: Bivalirudin
\nSynonyma: Bivalirudin, TFA;BIVALIRUDIN;BIVALIRUDIN TRIFLUOROACETATE;BITTERMELONP.E;Lidsk\u00fd bivalirudin;DPHE-PRO-ARG-PRO-GLY-GLY-GLY-GLY-ASN-GLY-ASP- PHE-GLU-GLU-LLE-PRO-GLU-GLU-TYR-LEU;Bivalirudin acet\u00e1t;Bivalirudin BG 8967, Hirulog, Hirulog I
\nCAS: 128270-60-0
\nMF: C98H138N24O33
\nMW: 2180.29
\nEINECS: 274-570-6
\nKategorie produkt\u016f: API;proteiny;Peptid
\nMol File: 128270-60-0.mol<\/p>\n

Bivalirudin je druh syntetick\u00fdch nov\u00fdch antikoagulanci\u00ed. Je to p\u0159\u00edm\u00fd, specifick\u00fd a reverzibiln\u00ed inhibitor trombinu. P\u016fvodn\u011b byl vyvinut \u0161v\u00fdcarsk\u00fdm basetem (Biogen). Pot\u00e9 byl p\u0159eveden na United States Medicines Company a schv\u00e1len pro uveden\u00ed na trh ve Spojen\u00fdch st\u00e1tech v roce 2000. Jeho antikoagula\u010dn\u00ed slo\u017ekou je druh 20 peptid\u016f odvozen\u00fdch od hirudinu. Bivalirudin se m\u016f\u017ee specificky v\u00e1zat na katalytick\u00e9 m\u00edsto a na vazebn\u00e9 m\u00edsto pro anion, a\u0165 u\u017e trombin, kter\u00fd je v krevn\u00edm ob\u011bhu, nebo trombin v\u00e1zan\u00fd na trombin, \u010d\u00edm\u017e p\u0159\u00edmo inhibuje aktivitu trombinu. A jeho role je charakterizov\u00e1na kr\u00e1tk\u00fdm, vratn\u00fdm. \u010casn\u00e9 klinick\u00e9 studie ukazuj\u00ed, \u017ee antikoagula\u010dn\u00ed l\u00e9\u010dba bivalirudinem je dobr\u00e1. A v\u00fdskyt krv\u00e1civ\u00fdch p\u0159\u00edhod je n\u00edzk\u00fd. Jeho pou\u017eit\u00ed je tedy bezpe\u010dn\u011bj\u0161\u00ed ne\u017e tradi\u010dn\u00ed heparinov\u00e1 terapie. Pou\u017e\u00edv\u00e1 se hlavn\u011b k prevenci angioplastick\u00e9 interven\u010dn\u00ed l\u00e9\u010dby ischemick\u00fdch komplikac\u00ed nestabiln\u00ed anginy pectoris p\u0159ed a po.<\/p>\n

Bivalirudin CAS 128270-60-0 Chemick\u00e9 vlastnosti<\/strong>
\nhustota 1,52\u00b10,1 g\/cm3 (p\u0159edpov\u011bzeno)
\ntepl. -20\u00b0C
\nforma pr\u00e1\u0161ku
\nbarva b\u00edl\u00e1 a\u017e t\u00e9m\u011b\u0159 b\u00edl\u00e1
\nInChIKey OIRCOABEOLEUMC-GEJPAHFPSA-N<\/p>\n

Pou\u017eit\u00ed bivalirudinu CAS 128270-60-0<\/strong>
\nAntikoagulant; antitrombotikum.<\/p>\n

Biluvudin je syntetick\u00e9 antikoagula\u010dn\u00ed l\u00e9\u010divo, 20-peptidov\u00fd analog hirudinu, kter\u00fd byl schv\u00e1len pro marketing ve Spojen\u00fdch st\u00e1tech v roce 2000. Bivalirudin se specificky v\u00e1\u017ee na katalytick\u00e9 m\u00edsto trombinu a aniontov\u00e9 vn\u011bj\u0161\u00ed vazebn\u00e9 m\u00edsto P\u0159\u00edmo inhibuje aktivitu trombinu a t\u00edm inhibuje reakce katalyzovan\u00e9 a indukovan\u00e9 trombinem a jeho p\u016fsoben\u00ed je reverzibiln\u00ed. Bivalirudin se pou\u017e\u00edv\u00e1 hlavn\u011b jako antikoagulans pro elektivn\u00ed perkut\u00e1nn\u00ed koron\u00e1rn\u00ed intervenci (PCI) u dosp\u011bl\u00fdch.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: Bivalirudin
\nCAS: 128270-60-0
\nMF: C98H138N24O33
\nMW: 2180,29
\nEINECS: 274-570-6
\nMol Soubor: 128270-60-0.mol<\/p>\n","protected":false},"featured_media":2265,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[407],"product_tag":[2387],"class_list":{"0":"post-7385","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-krev-a-cevni-peptid","7":"product_tag-bivalirudin-cas-128270-60-0-is-an-anticoagulant-for-lab-research-cs","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/7385","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=7385"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2265"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=7385"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=7385"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=7385"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=7385"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}