{"id":7398,"date":"2021-12-16T07:57:38","date_gmt":"2021-12-16T12:57:38","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-pro-zvyseni-krevniho-tlaku\/"},"modified":"2021-12-16T07:57:38","modified_gmt":"2021-12-16T12:57:38","slug":"angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-pro-zvyseni-krevniho-tlaku","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-pro-zvyseni-krevniho-tlaku\/","title":{"rendered":"Angiotensin II\/ANGIOTENSIN II, HUMAN CAS 4474-91-3 Pro zv\u00fd\u0161en\u00ed krevn\u00edho tlaku"},"content":{"rendered":"

Angiotensin II\/ANGIOTENSIN II, HUMAN CAS 4474-91-3 Pro zv\u00fd\u0161en\u00ed krevn\u00edho tlaku<\/strong><\/h2>\n

N\u00e1zev produktu: ANGIOTENSIN II, HUMAN
\nSekvence: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
\nSynonyma: DRVYIHPF;[ILE5]-ANGIOTENSIN 2;HYPERTENZE II \u010cLOV\u011aK;L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE;H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH;FLUORESCEIN-NHCS-NH-ASP-ARG- VAL-TYR-ILE-HIS-PRO-PHE-OH;ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O;ANGIOTENSIN II, HUMAN
\nCAS: 4474-91-3<& >MF: C50H71N13O12
\nMW: 1046,2
\nEINECS: 2017-001-1
\nKategorie produkt\u016f: Angiotensin;peptid
\nMol Soubor: 4474-91-3.mol<\/p>\n

Je to Je zn\u00e1mo, \u017ee n\u00e1dorov\u00e9 tk\u00e1n\u011b v\u010detn\u011b metastatick\u00fdch lymfatick\u00fdch uzlin jsou slo\u017eeny z nov\u011b rostouc\u00edch c\u00e9v, kter\u00e9 postr\u00e1daj\u00ed autoregulaci krevn\u00edho toku a jsou pouze sekund\u00e1rn\u011b ovlivn\u011bny odpov\u00eddaj\u00edc\u00edmi somatick\u00fdmi c\u00e9vami. Lidsk\u00fd angiotenzin II (AT II). vazopresor, byl zaveden v Japonsku ke zlep\u0161en\u00ed \u00fa\u010dinnosti syst\u00e9mov\u00e9 chemoterapie. U pacient\u016f s r\u016fzn\u00fdmi pokro\u010dil\u00fdmi n\u00e1dory iv infuze AT II k dosa\u017een\u00ed pr\u016fm\u011brn\u00e9ho krevn\u00edho tlaku 1,5n\u00e1sobku v\u00fdchoz\u00ed hodnoty (ale ne v\u00edce ne\u017e 150 mm Hg), po n\u00ed\u017e n\u00e1sleduje bolusov\u00e1 injekce konven\u010dn\u00edch cytotoxick\u00fdch l\u00e1tek, zvy\u0161uje pr\u016ftok krve v n\u00e1dorov\u00fdch tk\u00e1n\u00edch 5-7kr\u00e1t a proto zvy\u0161uje dod\u00e1vku l\u00e9\u010diva do c\u00edlov\u00e9 tk\u00e1n\u011b, co\u017e vede ke zv\u00fd\u0161en\u00fdm chemoterapeutick\u00fdm \u00fa\u010dink\u016fm. Tento re\u017eim chemoterapie s indukovanou hypertenz\u00ed lze prov\u00e1d\u011bt bezpe\u010dn\u011b s minim\u00e1ln\u00edmi vedlej\u0161\u00edmi \u00fa\u010dinky.<\/p>\n

Angiotensin II\/ANGIOTENSIN II, HUMAN CAS 4474-91-3 Chemick\u00e9 vlastnosti<\/strong>
\nBod varu 809,08\u00b0C (hrub\u00fd odhad)<& >hustota 1,1257 (hrub\u00fd odhad)
\nindex lomu 1,6700 (odhad)
\nRTECS BW2165000
\ntepl. Uchov\u00e1vejte v temnu, v inertn\u00ed atmosf\u00e9\u0159e, skladujte v mraz\u00e1ku, do -20\u00b0C
\nforma pr\u00e1\u0161ku
\npka pK1: 10,37 (25\u00b0C)
\nbarva oran\u017eov\u00e1
\nrozpustnost ve vod\u011b rozpustn\u00fd ve vod\u011b (25 mg \/ml) a 5% kyselina octov\u00e1 (1 mg\/ml).
\nInChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
\nCAS DataBase Reference 4474-91-3<\/p>\n

Funkce a aplikace angiotensinu II\/ANGIOTENSIN II, HUMAN CAS 4474-91-3<\/strong>
\nAngiotensin II je kr\u00e1tk\u00fd peptid slo\u017een\u00fd z 8 aminokyselin a jeho fyziologickou funkc\u00ed je p\u0159edev\u0161\u00edm zvy\u0161ovat krevn\u00ed tlak sta\u017een\u00edm mal\u00fdch tepen v cel\u00e9m t\u011ble. Krom\u011b toho m\u016f\u017ee tak\u00e9 podporovat sekreci aldosteronu k\u016frou nadledvin, kter\u00e1 p\u016fsob\u00ed na ledvinov\u00e9 tubuly, aby uchovala sod\u00edk, vodu a drasl\u00edk, a t\u00edm zp\u016fsobuje zv\u00fd\u0161en\u00ed objemu krve a krevn\u00edho tlaku.<\/p>\n

Pou\u017eit\u00ed angiotensinu II\/ ANGIOTENSIN II, LIDSK\u00dd CAS 4474-91-3<\/strong>
\n1. Kardiopulmon\u00e1ln\u00ed resuscitace \u2013 dosud neschv\u00e1len\u00e1 aplikace
\n2. Peptid zapojen\u00fd do regulace krevn\u00edho tlaku
\n3. Angiotensin II je peptidov\u00fd hormon zn\u00e1m\u00fd nejl\u00e9pe jako vazokonstriktor s \u00fast\u0159edn\u00ed rol\u00ed p\u0159i chronick\u00e9 hypertenzi, srde\u010dn\u00edm selh\u00e1n\u00ed a mrtvici. Je to oktapeptid, kter\u00fd se typicky vytv\u00e1\u0159\u00ed odstran\u011bn\u00edm dvou zbytk\u016f z angiotensinu I enzymem konvertuj\u00edc\u00edm angiotenzin (ACE). Angiotensin II je ligand pro alespo\u0148 dva odli\u0161n\u00e9 receptory, AT1 a AT2, z nich\u017e ka\u017ed\u00fd vyvol\u00e1v\u00e1 odli\u0161n\u00e9 sign\u00e1ln\u00ed dr\u00e1hy a fyziologick\u00e9 reakce. V\u00fdvoj antagonist\u016f pro specifick\u00e9 subtypy receptoru angiotensinu II p\u0159edstavuje cennou alternativu k ACE inhibitor\u016fm.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: ANGIOTENSIN II, HUMAN
\nCAS: 4474-91-3
\nMF: C50H71N13O12
\nMW: 1046,2
\nEINECS: 2017-001-1
\nMol File: 4474-91-3 .mol<\/p>\n","protected":false},"featured_media":2160,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[407],"product_tag":[2339,2361],"class_list":{"0":"post-7398","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-krev-a-cevni-peptid","7":"product_tag-angiotensin-ii-angiotensin-ii-cs","8":"product_tag-human-cas-4474-91-3-for-blood-pressure-raising-cs","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/7398","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=7398"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2160"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=7398"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=7398"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=7398"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=7398"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}