{"id":7732,"date":"2021-12-16T10:30:00","date_gmt":"2021-12-16T15:30:00","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-cilengitide-cas-188968-51-6-pro-laboratorni-vyzkum\/"},"modified":"2021-12-16T10:30:00","modified_gmt":"2021-12-16T15:30:00","slug":"puya-supply-cilengitide-cas-188968-51-6-pro-laboratorni-vyzkum","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/puya-supply-cilengitide-cas-188968-51-6-pro-laboratorni-vyzkum\/","title":{"rendered":"Puya Supply Cilengitide CAS 188968-51-6 pro laboratorn\u00ed v\u00fdzkum"},"content":{"rendered":"

Puya Supply Cilengitide CAS 188968-51-6 pro laboratorn\u00ed v\u00fdzkum<\/strong><\/h2>\n

N\u00e1zev produktu: cilengitid
\nSekvence: cyklo(Arg-Gly-Asp-D-Phe-N-Me-Val)
\nSynonyma: 2-[(2S,5R,8S,11S)-5- benzyl-11-[3-(diaminomethylidenamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyklopentadec-2 kyselina -yl]octov\u00e1; Cyklo(L-arginylglycyl-L-aspartyl-D-fenylalanyl-N-methyl-L-valyl); Cilengitid (EMD121974,NSC-707544); Cilengitid; C(RGDf-Me-V);EMD 121974;EMD-121974;EMD121974;CS-1500;CS-2674
\nCAS: 188968-51-6
\nMF: C27H40N8O7
\nMW: 588,66
\nEINECS: Inhibitory
\nProdukty &>Mol File: 188968-51-6.mol<\/p>\n

Cilengitid je cyklick\u00fd peptid obsahuj\u00edc\u00ed sekvenci RGD. Peptid je zalo\u017een na integrinov\u00e9m ligandu avp3 in vivo a byl z\u00edsk\u00e1n kombinac\u00ed cyklizace, prostorov\u00e9ho screeningu a methyla\u010dn\u00edho skenov\u00e1n\u00ed, s vysokou afinitou a selektivitou pro avp3 integriny. Testy uk\u00e1zaly, \u017ee peptid m\u016f\u017ee nejen l\u00e9pe inhibovat r\u016fst melanomu a glioblastomu, ale tak\u00e9 m\u016f\u017ee zlep\u0161it rychlost vyl\u00e9\u010den\u00ed jin\u00fdch n\u00e1dor\u016f, jako jsou spinocelul\u00e1rn\u00ed n\u00e1dory hlavy a krku v kombinaci s radia\u010dn\u00ed terapi\u00ed, kter\u00e1 m\u00e1 dobr\u00e9 vyhl\u00eddky na trhu a potenci\u00e1l. . P\u0159i synt\u00e9ze peptid\u016f byl Cilengitide vyroben kombinac\u00ed technologie synt\u00e9zy peptid\u016f na pevn\u00e9 f\u00e1zi s technologi\u00ed synt\u00e9zy peptid\u016f v kapaln\u00e9 f\u00e1zi.<\/p>\n

cilengitide CAS 188968-51-6 Chemick\u00e9 vlastnosti<\/strong>
\nhustota 1,41\u00b10,1 g\/cm3 (p\u0159edpov\u011bzeno)< &>tepl. -20\u00b0C
\nforma pr\u00e1\u0161ku
\npka 4,01\u00b10,10(p\u0159edpoklad)
\nbarva b\u00edl\u00e1 a\u017e b\u00e9\u017eov\u00e1<\/p>\n

Pou\u017eit\u00ed cilengitidu CAS 188968-51-6<\/strong>
\nInhibitor angiogeneze.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: cilengitid
\nCAS: 188968-51-6
\nMF: C27H40N8O7
\nMW: 588,66
\nMol Soubor: 188968-51-6.mol<\/p>\n","protected":false},"featured_media":2202,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[397],"product_tag":[2032],"class_list":{"0":"post-7732","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-protinadorovy-peptid","7":"product_tag-puya-supply-cilengitide-cas-188968-51-6-for-lab-research-cs","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/7732","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=7732"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2202"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=7732"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=7732"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=7732"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=7732"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}