{"id":7828,"date":"2021-12-16T11:16:34","date_gmt":"2021-12-16T16:16:34","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/dsip-spanek-vyvolavajici-peptid-cas-62568-57-4-pomoc-pro-dobry-spanek\/"},"modified":"2021-12-16T11:16:34","modified_gmt":"2021-12-16T16:16:34","slug":"dsip-spanek-vyvolavajici-peptid-cas-62568-57-4-pomoc-pro-dobry-spanek","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/dsip-spanek-vyvolavajici-peptid-cas-62568-57-4-pomoc-pro-dobry-spanek\/","title":{"rendered":"DSIP\/SP\u00c1NEK VYVOL\u00c1VAJ\u00cdC\u00cd PEPTID CAS 62568-57-4 Pomoc pro dobr\u00fd sp\u00e1nek"},"content":{"rendered":"

Drotaverin Hidroklorida \/ Drotaverin Hcl CAS 985-12-6<\/strong><\/h2>\n

N\u00e1zev produktu: DSIP
\nSynonyma: PEPTIDE VYVOL\u00c1VAJ\u00cdC\u00cd SP\u00c1NEK;WAGGDASGE;TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER- GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O;DELTA PEPTID VYVOL\u00c1VAJ\u00cdC\u00cd SP\u00c1NEK;DELTA PEPTID NAVODUJ\u00cdC\u00cd SP\u00c1NEK 4H2O;DSIP
\nCAS: 62568-57-4
\nMF : C35H48N10O15
\nMW: 848,82
\nEINECS: 211-519-9
\nKategorie produkt\u016f: Peptid
\nMol File: 62568-57-4.mol<\/p>\n

Delta sp\u00e1nek indukuj\u00edc\u00ed peptid, zkr\u00e1cen\u011b DSIP, je neuropeptid, kter\u00fd p\u0159i infuzi do mesodiencefalick\u00e9 komory p\u0159\u00edjemc\u016f kr\u00e1l\u00edk\u016f indukuje v\u0159etenovou a delta EEG aktivitu a sn\u00ed\u017eenou motorickou aktivitu.<\/p>\n

DSIP CAS 985-12-6 Chemick\u00e9 vlastnosti<\/strong>
\nBod varu 1522,7\u00b165,0 \u00b0C (P\u0159edpokl\u00e1dan\u00e1)
\nhustota 1,458\u00b10,06 g\/cm3 (P\u0159edpokl\u00e1dan\u00e1)
\ntepl. \u221220\u00b0C
\npka 3,18\u00b10,10(p\u0159edpoklad)
\nRozpustnost ve vod\u011b Rozpustn\u00fd ve vod\u011b p\u0159i 0,5mg\/ml
\nInChIKey ZRZROXNBKJAOKB-GFVHOAGBSA-N<\/p>\n

Funkce DSIP<\/strong>
\nMnoho rol\u00ed pro DSIP byly navr\u017eeny na z\u00e1klad\u011b v\u00fdzkumu prov\u00e1d\u011bn\u00e9ho za pou\u017eit\u00ed peptidov\u00fdch analog\u016f s v\u011bt\u0161\u00ed molekul\u00e1rn\u00ed stabilitou a m\u011b\u0159en\u00edm imunologick\u00e9 odpov\u011bdi podobn\u00e9 DSIP (DSIP-LI) injekc\u00ed DSIP antis\u00e9ra a protil\u00e1tek<\/p>\n

Role v endokrinn\u00ed regulaci<\/strong>
\nSni\u017euje baz\u00e1ln\u00ed hladinu kortikotropinu a blokuje jeho uvol\u0148ov\u00e1n\u00ed.
\nStimuluje uvol\u0148ov\u00e1n\u00ed luteiniza\u010dn\u00edho hormonu (LH).
\nStimuluje uvol\u0148ov\u00e1n\u00ed somatoliberinu a sekreci somatotropinu a inhibuje sekreci somatostatinu.<\/p>\n

Struktura a interakce<\/strong>
\nDSIP je amfifiln\u00ed peptid o molekulov\u00e9 hmotnosti 850 dalton\u016f s aminokyselinov\u00fdm motivem:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C
\nByl nalezen ve voln\u00e9 i v\u00e1zan\u00e9 form\u011b v hypotalamu, limbick\u00fd syst\u00e9m a hypof\u00fdza i r\u016fzn\u00e9 perifern\u00ed org\u00e1ny, tk\u00e1n\u011b a t\u011blesn\u00e9 tekutiny.[5] V hypof\u00fdze se lokalizuje s mnoha peptidov\u00fdmi a nepeptidov\u00fdmi medi\u00e1tory, jako je intermedi\u00e1rn\u00ed peptid podobn\u00fd kortikotropinu (CLIP), adrenokortikotropn\u00ed hormon (ACTH), hormon stimuluj\u00edc\u00ed melanocyty (MSH), hormon stimuluj\u00edc\u00ed \u0161t\u00edtnou \u017el\u00e1zu (TSH) a koncentruj\u00edc\u00ed melanin. hormon (MCH). Je hojn\u00fd ve st\u0159evn\u00edch sekre\u010dn\u00edch bu\u0148k\u00e1ch a ve slinivce b\u0159i\u0161n\u00ed, kde se lokalizuje spole\u010dn\u011b s glukagonem.
\nIn vitro bylo zji\u0161t\u011bno, \u017ee m\u00e1 n\u00edzkou molekul\u00e1rn\u00ed stabilitu s polo\u010dasem pouze 15 minut v d\u016fsledku p\u016fsoben\u00ed specifick\u00e9 Bylo navr\u017eeno, \u017ee v t\u011ble vytv\u00e1\u0159\u00ed komplexy s nosn\u00fdmi proteiny, aby se zabr\u00e1nilo degradaci, nebo existuje jako slo\u017eka velk\u00e9 prekurzorov\u00e9 molekuly, ale dosud nebyla pro tento prekurzor nalezena \u017e\u00e1dn\u00e1 struktura nebo gen.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: DSIP
\nCAS: 62568-57-4
\nMF: C35H48N10O15
\nMW: 848,82
\nEINECS: 211-519-9
\nMol Soubor: 62568-57-4.mol<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[515,515],"product_tag":[1950],"class_list":{"0":"post-7828","1":"product","2":"type-product","3":"status-publish","5":"product_cat-jine-peptidy","7":"product_tag-dsip-sleep-inducing-peptide-cas-62568-57-4-help-for-sleep-well-cs","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/7828","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=7828"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=7828"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=7828"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=7828"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=7828"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}