{"id":8146,"date":"2021-12-16T12:21:03","date_gmt":"2021-12-16T17:21:03","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/triptorelin-triptorelin-acetat-cas-57773-63-4-pro-lecbu-rakoviny-prostaty-a-rakoviny-prsu\/"},"modified":"2021-12-16T12:21:03","modified_gmt":"2021-12-16T17:21:03","slug":"triptorelin-triptorelin-acetat-cas-57773-63-4-pro-lecbu-rakoviny-prostaty-a-rakoviny-prsu","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/triptorelin-triptorelin-acetat-cas-57773-63-4-pro-lecbu-rakoviny-prostaty-a-rakoviny-prsu\/","title":{"rendered":"Triptorelin\/ Triptorelin acet\u00e1t CAS 57773-63-4 pro l\u00e9\u010dbu rakoviny prostaty a rakoviny prsu"},"content":{"rendered":"

Triptorelin\/ Triptorelin acet\u00e1t CAS 57773-63-4 pro l\u00e9\u010dbu rakoviny prostaty a rakoviny prsu<\/strong><\/h2>\n

N\u00e1zev produktu: Triptorelin
\nSynonyma: PGLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2;PYROGLU-HIS-TRP-SER-TYR-D-TRP- LEU-ARG-PRO-GLY NH2;PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2;PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG -PRO-GLY-NH2 PAMOATE SALT;TRIPTORELIN PAMOATE;TRIPTORELIN ACETATE;TRIPTORELIN AMIDE;TRIPTORELIN, [DTRP6]-LH-RH, AMIDE
\nCAS: 57773-63-4
\nMF: C64H82N18O13
\nMW: 1311.47
\nEINECS: 637-328-4
\nKategorie produkt\u016f: Deriv\u00e1ty aminokyselin;Peptid
\nMol Soubor: 57773-63-4.mol<\/p>\n

Triptoreli je syntetick\u00fd analog dekapeptidu uvol\u0148uj\u00edc\u00ed hormon (LHRH). Triptoreli, kter\u00fd m\u00e1 v\u011bt\u0161\u00ed \u00fa\u010dinnost ne\u017e endogenn\u00ed LHRH, reverzibiln\u011b potla\u010duje sekreci gonadotropinu. Po chronick\u00e9m kontinu\u00e1ln\u00edm pod\u00e1v\u00e1n\u00ed tato l\u00e1tka zp\u016fsobuje trval\u00e9 sn\u00ed\u017een\u00ed produkce LH a FSH a testikul\u00e1rn\u00ed a ovari\u00e1ln\u00ed steroidogenezi. S\u00e9rov\u00e9 koncentrace mohou klesnout na hladiny typicky pozorovan\u00e9 u chirurgicky kastrovan\u00fdch mu\u017e\u016f.<\/p>\n

Triptorelin\/ Triptorelin acet\u00e1t CAS 57773-63-4 Chemick\u00e9 vlastnosti<\/strong>
\nalfa D23 -58,8\u00b0 (c = 0,33 v kyselin\u011b octov\u00e9)
\n hustota 1,52\u00b10,1 g\/cm3 (P\u0159edpov\u011bzeno)
\ntepl. -20\u00b0C
\npka 9,82\u00b10,15(p\u0159edpoklad)
\npr\u00e1\u0161kov\u00e1 forma
\nInChIKey HPPONSCISKROOD-OYLNGHKZSA-N
\nReferen\u010dn\u00ed \u010d\u00edslo datab\u00e1ze CAS 57773-63-4 (Referen\u010dn\u00ed \u010d\u00edslo datab\u00e1ze CAS)<\/p>\n

Funkce a aplikace triptorelinu\/triptorelin acet\u00e1tu CAS 57773-63-4<\/strong>
\nTriptoreli lze pou\u017e\u00edt p\u0159i l\u00e9\u010db\u011b rakoviny reaguj\u00edc\u00ed na hormony, jako je rakovina prostaty nebo prsu, p\u0159ed\u010dasn\u00e1 puberta, stavy z\u00e1visl\u00e9 na estrogenu (jako je endometri\u00f3za nebo d\u011bloha myomy) a p\u0159i asistovan\u00e9 reprodukci. Pou\u017e\u00edv\u00e1 se tak\u00e9 jako terapie poruchy genderov\u00e9 identity.<\/p>\n

Triptorelin pamo\u00e1t je dal\u0161\u00edm superagonistou GnRH, kter\u00fd stejn\u011b jako nafarelin acet\u00e1t obsahuje pouze jednu substituci aminokyseliny (D-Trp6 za Gly6) ve srovn\u00e1n\u00ed s p\u0159irozen\u00fdm hormonem. P\u0159i l\u00e9\u010db\u011b pokro\u010dil\u00e9ho karcinomu prostaty je d\u016fle\u017eit\u00e9 sn\u00ed\u017eit hladinu testosteronu v s\u00e9ru na velmi n\u00edzk\u00e9 hodnoty, \u010deho\u017e lze dos\u00e1hnout chirurgicky orchiektomi\u00ed. Pokud je tato chirurgick\u00e1 metoda pro pacientku nep\u0159ijateln\u00e1, je alternativn\u00edm p\u0159\u00edstupem \u201echemick\u00e1 kastrace\u201c, kter\u00e9 lze dos\u00e1hnout pou\u017eit\u00edm estrogenov\u00e9 terapie, leuprolidu, goserelinu nebo histrelinacet\u00e1t\u016f a nyn\u00ed triptorelin pamo\u00e1tu. Tento produkt je k dispozici pro IM depotn\u00ed injekci (m\u011bs\u00ed\u010dn\u011b nebo ka\u017ed\u00e9 3 m\u011bs\u00edce), kdy koncentrace testosteronu v s\u00e9ru klesne na \u00farove\u0148 obecn\u011b pozorovanou u chirurgicky kastrovan\u00fdch mu\u017e\u016f.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: Triptorelin
\nCAS: 57773-63-4
\nMF: C64H82N18O13
\nMW: 1311,47
\nEINECS: 637-328-4
\nMol Soubor: 57773-63-4.mol<\/p>\n","protected":false},"featured_media":2286,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[397],"product_tag":[1507],"class_list":{"0":"post-8146","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-protinadorovy-peptid","7":"product_tag-triptorelin-triptorelin-acetate-cas-57773-63-4-for-treat-prostate-cancer-and-breast-cancer-cs","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/8146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=8146"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2286"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=8146"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=8146"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=8146"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=8146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}