{"id":8516,"date":"2021-12-17T01:44:17","date_gmt":"2021-12-17T06:44:17","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/liraglutide-cas-204656-20-2-pro-hubnuti-a-lecbu-diabetu-2\/"},"modified":"2021-12-17T01:44:17","modified_gmt":"2021-12-17T06:44:17","slug":"liraglutide-cas-204656-20-2-pro-hubnuti-a-lecbu-diabetu-2","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/liraglutide-cas-204656-20-2-pro-hubnuti-a-lecbu-diabetu-2\/","title":{"rendered":"Liraglutide CAS 204656-20-2 pro hubnut\u00ed a l\u00e9\u010dbu diabetu 2."},"content":{"rendered":"

Liraglutide CAS 204656-20-2 pro hubnut\u00ed a l\u00e9\u010dbu diabetu 2.<\/strong><\/h2>\n

N\u00e1zev produktu: Liraglutid
\nSynonyma: Liraglutid;Glycin, L-histidyl-L-alanyl-L-alfa-glutamylglycyl-L-threonyl-L-fenylalanyl-L-threonyl-L-seryl-L-alfa- aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alfa-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-(N-(1-oxohexadecyl) -L-gama-glutamyl)-L-lysyl-L-alfa-glutamyl-L-fenylalanyl-L-isoleucyl-L-alanyl-L-tryptofyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl- ;Liraglutida;Liraglutida [inn-\u0161pan\u011bl\u0161tina];Liraglutid [usan:inn];Liraglutidum;Liraglutidum [inn-latinsky];N26-(hexadekanoyl-gama-glutamyl)-(34-arginin)glp-1-(7-37) -peptid
\nCAS: 204656-20-2
\nMF: C172H265N43O51
\nMW: 3751,202
\nEINECS: 810-818-7
\nKategorie produkt\u016f: GLP
\nMol File: 20465 -2.mol<\/p>\n

Liraglutid je \u010dir\u00fd, bezbarv\u00fd roztok. L\u00e9kov\u00e1 forma je subkut\u00e1nn\u00ed injekce. Po v\u00edce ne\u017e 10 letech v\u00fdzkumu a v\u00fdvoje m\u00e1 liraglutid mnoho funkc\u00ed, jako je podpora regenerace bun\u011bk ostr\u016fvk\u016f, sn\u00ed\u017een\u00ed hladiny cukru v krvi, sn\u00ed\u017een\u00ed hmotnosti a ochrana kardiovaskul\u00e1rn\u00edho syst\u00e9mu. Zna\u010dka Victoza se pou\u017e\u00edv\u00e1 k l\u00e9\u010db\u011b diabetu 2. typu a zna\u010dka Saxenda se pou\u017e\u00edv\u00e1 k l\u00e9\u010db\u011b chronick\u00e9 obezity. Jako dopln\u011bk ke kontrole stravy a fyzick\u00e9mu cvi\u010den\u00ed. Liraglutid je acylovan\u00fd agonista receptoru pro lidsk\u00fd glukagonu podobn\u00fd peptid-1 (GLP-1), kter\u00fd m\u00e1 97% homologii aminokyselinov\u00e9 sekvence s lidskou endogenn\u00ed GChemicalbookLP-1 (7-37) a zachov\u00e1v\u00e1 si v\u0161echny biologick\u00e9 aktivity GLP- 1 a m\u00e1 agonismus receptoru GLP-1. Prost\u0159ednictv\u00edm exprese rekombinantn\u00ed DNA v Saccharomyces cerevisiae se jej\u00ed molekul\u00e1rn\u00ed struktura li\u0161\u00ed pouze o jednu aminokyselinu od p\u0159irozen\u00e9 molekuly GLP-1. Struktura pouze modifikuje n\u00e1sleduj\u00edc\u00ed dv\u011b \u010d\u00e1sti GLP-1: to znamen\u00e1, \u017ee 34. lysin je nahrazen argininem. Kysel\u00e1 substituce krom\u011b p\u0159id\u00e1n\u00ed 16-uhl\u00edkov\u00e9ho postrann\u00edho \u0159et\u011bzce palmitoyl mastn\u00e9 kyseliny zprost\u0159edkovan\u00e9ho kyselinou glutamovou na 26. lysinu.<\/p>\n

Funkce liraglutidu CAS 204656-20-2<\/strong> <\/p>\n

1. P\u016fsob\u00ed zp\u016fsobem z\u00e1visl\u00fdm na gluk\u00f3ze, co\u017e znamen\u00e1, \u017ee bude stimulovat sekreci inzulinu pouze tehdy, kdy\u017e jsou hladiny gluk\u00f3zy v krvi vy\u0161\u0161\u00ed ne\u017e norm\u00e1ln\u011b, \u010d\u00edm\u017e se zabr\u00e1n\u00ed \u201ep\u0159ekro\u010den\u00ed\u201c. V d\u016fsledku toho vykazuje zanedbateln\u00e9 riziko hypoglyk\u00e9mie.
\n2.M\u00e1 potenci\u00e1l inhibovat apopt\u00f3zu a stimulovat regeneraci beta bun\u011bk (pozorovan\u00e9 ve studi\u00edch na zv\u00ed\u0159atech).
\n3.Sni\u017euje chu\u0165 k j\u00eddlu a inhibuje n\u00e1r\u016fst t\u011blesn\u00e9 hmotnosti, jak je uk\u00e1z\u00e1no v p\u0159\u00edm\u00e9 studii versus glimepirid.
\n4.Sni\u017euje hladiny triglycerid\u016f v krvi.<\/p>\n

Aplikace liraglutidu CAS 204656-20-2<\/strong>
\n1.L\u00e9\u010dba diabetu 2. typu.
\n 2.L\u00e9\u010dba obezity.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: Liraglutide
\nCAS: 204656-20-2
\nMF: C172H265N43O51
\nMW: 3751.202
\nEINECS: 810-818-7
\nKategorie produkt\u016f: GLP
\n4656 Mol File: 2 -20-2.mol<\/p>\n","protected":false},"featured_media":2118,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[339],"product_tag":[1209],"class_list":{"0":"post-8516","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptid-diabetu","7":"product_tag-liraglutide-cas-204656-20-2-for-weight-loss-and-treat-for-type-2-diabetes-cs","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/8516","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=8516"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2118"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=8516"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=8516"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=8516"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=8516"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}