{"id":8724,"date":"2021-12-17T03:02:06","date_gmt":"2021-12-17T08:02:06","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/exenatid-acetat-cas-141732-76-5-pouzivany-jako-enteralni-hypoglykemicke-cinidlo\/"},"modified":"2021-12-17T03:02:06","modified_gmt":"2021-12-17T08:02:06","slug":"exenatid-acetat-cas-141732-76-5-pouzivany-jako-enteralni-hypoglykemicke-cinidlo","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/exenatid-acetat-cas-141732-76-5-pouzivany-jako-enteralni-hypoglykemicke-cinidlo\/","title":{"rendered":"Exenatid acet\u00e1t CAS 141732-76-5 pou\u017e\u00edvan\u00fd jako enter\u00e1ln\u00ed hypoglykemick\u00e9 \u010dinidlo"},"content":{"rendered":"

Exenatid acet\u00e1t CAS 141732-76-5 pou\u017e\u00edvan\u00fd jako enter\u00e1ln\u00ed hypoglykemick\u00e9 \u010dinidlo<\/strong><\/h2>\n

N\u00e1zev produktu: Exenatid acet\u00e1t
\nSynonyma: Exenatid;His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala -Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2};EXENATID ACETATE(EXENDIN -4);His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile- Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2;Exenatid Acettate; EXENATID ACETATE; ENFUVIRTID ACETATE; Extendin-4
\nCAS : 141732-76-5
\nMF: C186H286N50O62S
\nMW: 4244,60796
\nEINECS: 1592732-453-0
\nKategorie produkt\u016f: Agonisty;Z\u00e1klady a souvisej\u00edc\u00ed reagencie & Reagenty Pharmaceuticals;GLP
\nMol File: 141732-76-5.mol<\/p>\n

Aminokyselinov\u00e1 sekvence exenatid acet\u00e1tu se \u010d\u00e1ste\u010dn\u011b p\u0159ekr\u00fdv\u00e1 s lidsk\u00fdm GLP-1. Bylo prok\u00e1z\u00e1no, \u017ee exenatidacet\u00e1t se in vitro v\u00e1\u017ee na zn\u00e1m\u00fd lidsk\u00fd receptor GLP-1 a aktivuje jej. To znamen\u00e1, \u017ee za\u0159azen\u00edm cAMP (cyklick\u00fd adenosinmonofosf\u00e1t) nebo jin\u00fdch intracelul\u00e1rn\u00edch signaliza\u010dn\u00edch mechanism\u016f se zv\u00fd\u0161\u00ed na gluk\u00f3ze z\u00e1visl\u00e1 synt\u00e9za inzul\u00ednu a sekrece inzul\u00ednu pankreatick\u00fdmi \u03b2 bu\u0148kami v t\u011ble.<\/p>\n

Funkce a aplikace Exenatid acet\u00e1tu CAS 141732-76-5<\/strong>
\nAplikace exenatidacet\u00e1tu zp\u016fsobuje zv\u00fd\u0161en\u00ed acin\u00e1rn\u00edho cAMP bez stimulace uvol\u0148ov\u00e1n\u00ed amyl\u00e1zy. Jako inkretinov\u00e9 mimetikum p\u016fsob\u00ed exenatidacet\u00e1t jako agonista receptoru glukagonu podobn\u00e9ho peptidu-1 (GLP-1). Proto\u017ee GLP-1, i kdy\u017e s prodlou\u017eenou aktivitou, exenatidacet\u00e1t zvy\u0161uje postprandi\u00e1ln\u00ed produkci inzul\u00ednu a potla\u010duje sekreci glukagonu. Z tohoto d\u016fvodu na\u0161el exenatid acet\u00e1t pou\u017eit\u00ed jako l\u00e9k na diabetes II.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: Exenatid acet\u00e1t
\nCAS: 141732-76-5
\nMF: C186H286N50O62S
\nMW: 4244,60796
\nEINECS: 1592732-453-0
\nMol Soubor: 176173<\/p>\n","protected":false},"featured_media":2202,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[339],"product_tag":[998],"class_list":{"0":"post-8724","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptid-diabetu","7":"product_tag-exenatide-acetate-cas-141732-76-5-used-as-an-enteral-hypoglycemic-agent-cs","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/8724","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=8724"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2202"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=8724"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=8724"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=8724"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=8724"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}