{"id":8788,"date":"2021-12-17T03:06:10","date_gmt":"2021-12-17T08:06:10","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-degarelix-acetate-cas-214766-78-6-pouziva-se-k-lecbe-rakoviny-prostaty\/"},"modified":"2021-12-17T03:06:10","modified_gmt":"2021-12-17T08:06:10","slug":"puya-supply-degarelix-acetate-cas-214766-78-6-pouziva-se-k-lecbe-rakoviny-prostaty","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/puya-supply-degarelix-acetate-cas-214766-78-6-pouziva-se-k-lecbe-rakoviny-prostaty\/","title":{"rendered":"Puya Supply Degarelix Acetate CAS 214766-78-6 Pou\u017e\u00edv\u00e1 se k l\u00e9\u010db\u011b rakoviny prostaty"},"content":{"rendered":"

Puya Supply Degarelix Acetate CAS 214766-78-6 Pou\u017e\u00edv\u00e1 se k l\u00e9\u010db\u011b rakoviny prostaty<\/strong><\/h2>\n

N\u00e1zev produktu: DEGARELIX
\nSynonyma: DEGARELIX;Degarelix acet\u00e1t;N-acetyl-3-(2-naftyl)-D-alanyl-4-chlor-D-fenylalanyl-3-(3-pyridyl)-D -alanyl-L-seryl-4-[2,6-dioxohexahydropyrimidin-4(S)-ylkarboxamido]-L-fenylalanyl-4-ureido-D-fenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L- prolyl-D-alaninamid acet\u00e1t; Degarelix acet\u00e1tov\u00e1 s\u016fl; D-alaninamid, N-acetyl-3-(naftalen-2-yl)-D-alanyl-4-chlor-D-fenylalanyl-3-(pyridin-3-yl) -D-alanyl-L-seryl-4-((((4S)-2,6-dioxohexahydropyrimidin-4-yl)karbonyl)amino)-L-fenylalanyl-4-(karbamoylamino)-D-fenylalanyl-L-leucyl -N6-(1-methylethyl)-L-lysyl-L-prolyl-;Degarelix acet\u00e1t (FE-200486, Degarelix); FirMagon; Degarelix, Degarelix acet\u00e1t
\nCAS: 214766-78-6
\nMF: C82H103ClN18O16
\nMW: 1632,26
\nEINECS: 807-277-4
\nKategorie produkt\u016f: API
\nMol File: 214766-78-6.mol<\/p>\n

Antagonist\u00e9 GnRH se uk\u00e1zali jako \u00fa\u010dinn\u00e1 terapie hormon\u00e1ln\u011b regulovan\u00fdch rakovin, jako je prostata a n\u011bkter\u00e9 typy prsu. Jako analogy GnRH se kompetitivn\u011b a reverzibiln\u011b v\u00e1\u017eou na receptory GnRH v hypof\u00fdze, \u010d\u00edm\u017e blokuj\u00ed uvol\u0148ov\u00e1n\u00ed luteiniza\u010dn\u00edho hormonu (LH) a folikuly stimuluj\u00edc\u00edho hormonu (FSH). U mu\u017e\u016f sn\u00ed\u017een\u00ed LH spou\u0161t\u00ed ablaci sekrece testosteronu z varlat a tyto hladiny podobn\u00e9 kastraci jsou nezbytn\u00e9 pro efektivn\u00ed l\u00e9\u010dbu pokro\u010dil\u00e9ho karcinomu prostaty. Ve srovn\u00e1n\u00ed s agonisty GnRH netrp\u00ed antagonist\u00e9 potenci\u00e1ln\u00edm vzplanut\u00edm onemocn\u011bn\u00ed v d\u016fsledku po\u010d\u00e1te\u010dn\u00ed stimulace osy hypotalamus-hypof\u00fdza-gon\u00e1da p\u0159ed down-regulac\u00ed receptoru GnRH. Nav\u00edc antagonist\u00e9 GnRH poskytuj\u00ed prosp\u011b\u0161n\u00e9 \u00fa\u010dinky rychleji po d\u00e1vce a vedou k \u00fa\u010dinn\u011bj\u0161\u00edmu potla\u010den\u00ed hladin gonadotropinu. S ohledem na tuto skute\u010dnost byl degarelix acet\u00e1t uveden na trh jako antagonista GnRH t\u0159et\u00ed generace pro l\u00e9\u010dbu rakoviny prostaty a p\u0159ipojuje se k dal\u0161\u00edm p\u0159\u00edpravk\u016fm t\u0159et\u00ed generace, ganirelix a cetronelix, na trhu.<\/p>\n

Chemick\u00e9 vlastnosti Degarelix Acetate CAS 214766-78-6<\/strong>
\nhustota 1,325\u00b10,06 g\/cm3 (p\u0159edpokl\u00e1dan\u00e1)
\ntepl. Uchov\u00e1vejte na tmav\u00e9m m\u00edst\u011b, inertn\u00ed atmosf\u00e9ra, skladujte v mraz\u00e1ku, pod -20 \u00b0C
\npka 10,38\u00b10,40 (p\u0159edpoklad)<\/p>\n

Funkce a aplikace Degarelix Acetate CAS 214766-78-6<\/strong>
\nPokro\u010dil\u00fd hormon -dependentn\u00ed karcinom prostaty<\/p>\n

Desmopressin' (obchodn\u00ed n\u00e1zvy: DDAVP, DesmoMelt, Minirin, Minirin Melt, Octim, Stimate) je syntetick\u00e1 n\u00e1hrada vazopresinu, hormonu, kter\u00fd sni\u017euje tvorbu mo\u010di. M\u016f\u017ee se u\u017e\u00edvat naz\u00e1ln\u011b, intraven\u00f3zn\u011b nebo jako peror\u00e1ln\u00ed \u010di sublingv\u00e1ln\u00ed tableta. L\u00e9ka\u0159i p\u0159edepisuj\u00ed desmopresin nej\u010dast\u011bji k l\u00e9\u010db\u011b diabetes insipidus, no\u010dn\u00edho pomo\u010dov\u00e1n\u00ed nebo nykturie.<\/p>\n

M\u016f\u017ee se u\u017e\u00edvat naz\u00e1ln\u011b, intraven\u00f3zn\u011b nebo jako tablety. L\u00e9ka\u0159i p\u0159edepisuj\u00ed Desmopressin nej\u010dast\u011bji k l\u00e9\u010db\u011b diabetes insipidus nebo no\u010dn\u00ed enur\u00e9zy. Desmopressin' (1-desamino-8-D-arginin vasopresin) je modifikovan\u00e1 forma norm\u00e1ln\u00edho lidsk\u00e9ho hormonu arginin vasopresin, peptid obsahuj\u00edc\u00ed dev\u011bt aminokyselin. L\u00e9ka\u0159sk\u00e9 pou\u017eit\u00ed Desmopressin'acet\u00e1tu zahrnuje: (a) pomo\u010dov\u00e1n\u00ed; b) no\u010dn\u00ed pomo\u010dov\u00e1n\u00ed; (c) poruchy sr\u00e1\u017elivosti; (d) diabetes insipidus.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: DEGARELIX
\nCAS: 214766-78-6
\nMF: C82H103ClN18O16
\nMW: 1632,26
\nEINECS: 807-277-4
\nKategorie produkt\u016f: API
\nMol File: 2 -78-6.mol<\/p>\n","protected":false},"featured_media":2118,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[],"product_tag":[931],"class_list":{"0":"post-8788","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_tag-puya-supply-degarelix-acetate-cas-214766-78-6-used-for-treat-prostate-cancer-cs","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/8788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=8788"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2118"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=8788"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=8788"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=8788"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=8788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}