{"id":8915,"date":"2021-12-17T03:14:22","date_gmt":"2021-12-17T08:14:22","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/carbetocin-acetate-cas-37025-55-1-prevence-slabych-deloznich-kontrakci-a-poporodniho-krvaceni\/"},"modified":"2021-12-17T03:14:22","modified_gmt":"2021-12-17T08:14:22","slug":"carbetocin-acetate-cas-37025-55-1-prevence-slabych-deloznich-kontrakci-a-poporodniho-krvaceni","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/carbetocin-acetate-cas-37025-55-1-prevence-slabych-deloznich-kontrakci-a-poporodniho-krvaceni\/","title":{"rendered":"Carbetocin Acetate CAS 37025-55-1 Prevence slab\u00fdch d\u011blo\u017en\u00edch kontrakc\u00ed a poporodn\u00edho krv\u00e1cen\u00ed"},"content":{"rendered":"

Carbetocin Acetate CAS 37025-55-1 Prevence slab\u00fdch d\u011blo\u017en\u00edch kontrakc\u00ed a poporodn\u00edho krv\u00e1cen\u00ed<\/strong><\/h2>\n

N\u00e1zev produktu: CARBETOCIN
\nSynonyma: BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDOV\u00c1 VAZBA MEZI BUTYRYL-4-YL A CYS);BUTYRYL- TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2 trifluoracet\u00e1tov\u00e1 s\u016fl;(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUORACET\u00c1TOV\u00c1 S\u016eL;(BUTYRYL1,TYR(ME)2)-OXYTOCIN ;(BUTYRYL1,TYR(ME)2)-OXYTOCIN TRIFLUOROACET\u00c1T S\u016eL;KARBETOCIN;KARBETOCIN TRIFLUORACET\u00c1T S\u016eL;(2-O-METHYLTYROSIN)-DE-AMINO-1-CARBAOXYTOCIN
\nCAS:1251359S:1751357S : 988,17
\nEINECS: 253-312-6
\nKategorie produkt\u016f: Dal\u0161\u00ed API;Peptid;Receptor vazopresinu a oxytocinu;Meziprodukty a jemn\u00e9 chemik\u00e1lie;Farmaceutika:2-37M 1.mol<\/p>\n

Carbetocin je syntetick\u00fd dlouhodob\u011b p\u016fsob\u00edc\u00ed oxytocinov\u00fd 8-peptidov\u00fd analog s agonistick\u00fdmi vlastnostmi, s klinick\u00fdmi a farmakologick\u00fdmi vlastnostmi podobn\u00fdmi vlastnost p\u0159irozen\u011b se vyskytuj\u00edc\u00edho oxytocinu. Stejn\u011b jako oxytocin se i karbetocin v\u00e1\u017e\u00ed na oxytocinov\u00e9 receptory v hladk\u00e9m svalstvu d\u011blohy, co\u017e znamen\u00e1 rytmickou kontrakci d\u011blohy, kter\u00e1 zvy\u0161uje jej\u00ed frekvenci a zvy\u0161uje tonus d\u011blohy nad p\u016fvodn\u00ed kontrakce Chemicalbook. V net\u011bhotn\u00e9m stavu je hladina oxytocinov\u00fdch receptor\u016f v d\u011bloze n\u00edzk\u00e9, zvy\u0161uje se b\u011bhem t\u011bhotenstv\u00ed a vrchol\u00ed p\u0159i porodu. Proto kabergolin nep\u016fsob\u00ed na net\u011bhotnou d\u011blohu, ale m\u00e1 \u00fa\u010dinn\u00fd \u00fa\u010dinek na kontrakci d\u011blohy na t\u011bhotnou d\u011blohu a d\u011blohu, kter\u00e1 pr\u00e1v\u011b porodila.<\/p>\n

KARBETOCIN Chemick\u00e9 vlastnosti karbetocinu<\/strong>
\nalfa D – 69,0\u00b0 (c = 0,25 v 1M kyselin\u011b octov\u00e9)
\nBod varu 1477,9\u00b165,0 \u00b0C (p\u0159edpokl\u00e1dan\u00e1)
\nhustota 1,218\u00b10,06 g\/cm3 (p\u0159edpokl\u00e1dan\u00e1)
\nskladovac\u00ed tepl. -15\u00b0C
\nforma pr\u00e1\u0161ku
\npka 13,07\u00b10,70(p\u0159edpoklad)
\nbarva b\u00edl\u00e1 a\u017e b\u00e9\u017eov\u00e1<\/p>\n

Funkce a aplikace karbetocinu<\/strong>
\nPro pou\u017eit\u00ed po elektivn\u00ed epidur\u00e1ln\u00ed nebo bedern\u00ed anestezii p\u0159i c\u00edsa\u0159sk\u00e9m \u0159ezu porod, aby se slab\u00fdm d\u011blo\u017en\u00edm kontrakc\u00edm a poporodn\u00edm krv\u00e1cen\u00edm.
\nC\u00edsa\u0159sk\u00fd \u0159ez v jin\u00e9 anestezii pro akutn\u00ed c\u00edsa\u0159sk\u00fd \u0159ez, klasick\u00fd c\u00edsa\u0159sk\u00fd \u0159ez, epidur\u00e1ln\u00ed nebo spin\u00e1ln\u00ed anestezii nebo p\u0159\u00edtomnost matky se srde\u010dn\u00edm onemocn\u011bn\u00edm, anamn\u00e9za hypertenze, zn\u00e1m\u00e1 koagulopatie nebo jater, ledvin a endokrinn\u00edho onemocn\u011bn\u00ed (krom\u011b gesta\u010dn\u00edho diabetu) Pou\u017eit\u00ed karbetocinu nebylo studov\u00e1no. Pod\u00e1v\u00e1n\u00ed karbetocinu po vagin\u00e1ln\u00edm porodu nebylo \u0159\u00e1dn\u011b studov\u00e1no a d\u00e1vka nebyla stanovena.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: CARBETOCIN
\nCAS: 37025-55-1
\nMF: C45H69N11O12S
\nMW: 988,17
\nEINECS: 253-312-6
\nMol Soubor: 37025-55-1. mol<\/p>\n","protected":false},"featured_media":2202,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[432],"product_tag":[837],"class_list":{"0":"post-8915","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-urogenitalni-peptid","7":"product_tag-carbetocin-acetate-cas-37025-55-1-cs","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/8915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=8915"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2202"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=8915"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=8915"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=8915"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=8915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}