{"id":8922,"date":"2021-12-17T03:37:10","date_gmt":"2021-12-17T08:37:10","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/hot-sale-plecanatide-cas-467426-54-6-pouziti-k-lecbe-chronicke-idiopaticke-zacpy-cic\/"},"modified":"2023-11-18T06:36:58","modified_gmt":"2023-11-18T11:36:58","slug":"hot-sale-plecanatide-cas-467426-54-6-pouziti-k-lecbe-chronicke-idiopaticke-zacpy-cic","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/cs\/product\/hot-sale-plecanatide-cas-467426-54-6-pouziti-k-lecbe-chronicke-idiopaticke-zacpy-cic\/","title":{"rendered":"Hot Sale Plecanatide CAS 467426-54-6 Pou\u017eit\u00ed k l\u00e9\u010db\u011b chronick\u00e9 idiopatick\u00e9 z\u00e1cpy (CIC)"},"content":{"rendered":"

Hot Sale Plecanatide CAS 467426-54-6 Pou\u017eit\u00ed k l\u00e9\u010db\u011b chronick\u00e9 idiopatick\u00e9 z\u00e1cpy (CIC)<\/strong><\/h2>\n

N\u00e1zev produktu: Plecanatide
\nSynonyma: Plecanatide;ASN-ASP-GLU-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BOND CYS1&CYS3, CYS2&CYS4);Plecanatid Ne\u010distota;L-leucin, L-asparaginyl-L-\u03b1-aspartyl-L-\u03b1-glutamyl-L-cysteinyl-L-\u03b1-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L- asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyklick\u00fd (4\u219212),(7\u219215)-bis(disulfid);Plekanatid fandachem;Plekanatidov\u00e1 ne\u010distota;Plekanatid USP\/ EP\/BP;Prikanatid
\nCAS: 467426-54-6
\nMF: C65H104N18O26S4
\nMW: 1681,89
\nMol Soubor: 467426-54-6.mol<\/p>\n

Plecanatid je nov\u00fd l\u00e9k, kter\u00fd ovliv\u0148uje enzym guanyl\u00e1tcykl\u00e1zu, stimuluje sekreci st\u0159evn\u00edch tekutin a urychluje pohyby st\u0159ev. Peror\u00e1ln\u00ed peptid, slo\u017een\u00fd z 16 aminokyselin, je navr\u017een tak, aby napodoboval mo\u010dov\u00fd guanosin, lidsk\u00fd gastrointestin\u00e1ln\u00ed peptid. Prokainatid, p\u016fvodn\u011b vyvinut\u00fd spole\u010dnost\u00ed Callisto Pharmaceuticals ve Spojen\u00fdch st\u00e1tech a p\u0159eveden\u00fd na v\u00fdvoj do Synergy Pharmaceuticals, byl 19. ledna 2017 schv\u00e1len americk\u00fdm \u00da\u0159adem pro kontrolu potravin a l\u00e9\u010div (FDA) k uveden\u00ed na trh Chemick\u00e1 kniha 2017 pro l\u00e9\u010dbu CIC u dosp\u011bl\u00fdch. Prokainatid je analog uroguanosinu (uroguanylin) a obsahuje 16 Je analogem uroguanylinu, cyklick\u00e9ho peptidu obsahuj\u00edc\u00edho 16 aminokyselin a m\u00e1 funkci agonisty receptoru guanyl\u00e1tcykl\u00e1zy, kter\u00fd podporuje vylu\u010dov\u00e1n\u00ed sod\u00edku mo\u010d\u00ed, reguluje acidobazick\u00e9 ionty v gastrointestin\u00e1ln\u00edm traktu, indukuje tekutinu transport do gastrointestin\u00e1ln\u00edho traktu a zvy\u0161uje peristaltiku gastrointestin\u00e1ln\u00edho traktu.<\/p>\n

P\u0159elo\u017eeno s www.DeepL.com\/Translator (bezplatn\u00e1 verze)<\/p>\n

Funkce a aplikace Plecanatidu<\/strong>
\nProkainid je agonista receptoru guanylatecykl\u00e1zy-C (GC-C), kter\u00fd podporuje vylu\u010dov\u00e1n\u00ed sod\u00edku mo\u010d\u00ed, reguluje acidobazick\u00e9 ionty v gastrointestin\u00e1ln\u00edm traktu, indukuje transport tekutin do th e gastrointestin\u00e1ln\u00edho traktu a zvy\u0161uje peristaltiku v gastrointestin\u00e1ln\u00edm traktu a je indikov\u00e1n k l\u00e9\u010db\u011b CIC u dosp\u011bl\u00fdch.<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1zev produktu: Plecanatide
\nCAS: 467426-54-6
\nMF: C65H104N18O26S4
\nMW: 1681,89
\nMol Soubor: 467426-54-6.mol<\/strong><\/p>\n","protected":false},"featured_media":2160,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[446,446,446],"product_tag":[800],"class_list":{"0":"post-8922","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptid-gastrointestinalniho-systemu","9":"product_tag-plecanatide-cas-467426-54-6-use-for-treat-chronic-idiopathic-constipation-cs","10":"desktop-align-left","11":"tablet-align-left","12":"mobile-align-left","14":"first","15":"instock","16":"shipping-taxable","17":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product\/8922","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/comments?post=8922"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media\/2160"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/media?parent=8922"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_brand?post=8922"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_cat?post=8922"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/cs\/wp-json\/wp\/v2\/product_tag?post=8922"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}