{"id":7412,"date":"2021-12-16T07:58:31","date_gmt":"2021-12-16T12:58:31","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-til-blodtryksforhoejelse\/"},"modified":"2021-12-16T07:58:31","modified_gmt":"2021-12-16T12:58:31","slug":"angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-til-blodtryksforhoejelse","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/da\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-til-blodtryksforhoejelse\/","title":{"rendered":"Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Til blodtryksforh\u00f8jelse"},"content":{"rendered":"

Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Til blodtryksforh\u00f8jelse<\/strong><\/h2>\n

Produktnavn: ANGIOTENSIN II, HUMAN
\nSekvens: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
\nSynonymer: DRVYIHPF;[ILE5]-ANGIOTENSIN 2;HYPERTENSION II HUMAN;L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE;H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH;FLUORESCEIN-NHCS-NH-ASP-ARG- VAL-TYR-ILE-HIS-PRO-PHE-OH;ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O;ANGIOTENSIN II, HUMAN
\nCAS: 4474-91-3<& >MF: C50H71N13O12
\nMW: 1046,2
\nEINECS: 2017-001-1
\nProduktkategorier: Angiotensin;peptid
\nMol Fil: 4474-91-3.mol<\/p>\n

Det er kendt, at tumorv\u00e6v inklusive metastatiske lymfeknuder er sammensat af nyvoksende kar, som mangler blodgennemstr\u00f8mningsautoregulering og kun p\u00e5virkes sekund\u00e6rt af de reagerende somatiske kar. Humant angiotensin II (AT II). en vasopressor, blev introduceret i Japan for at forbedre effektiviteten af systemisk kemoterapi. Hos patienter med forskellige fremskredne kr\u00e6ftformer \u00f8ger iv infusion af AT II for at opn\u00e5 et gennemsnitligt blodtryk p\u00e5 1,5 gange baseline (men ikke over 150 mm Hg) efterfulgt af en bolusinjektion af konventionelle cytotoksiske midler blodgennemstr\u00f8mningen 5-7 gange i tumorv\u00e6v. og \u00f8ger derfor l\u00e6gemiddellevering til m\u00e5lv\u00e6vet, hvilket resulterer i forbedrede kemoterapeutiske virkninger. Denne kemoterapibehandling med induceret hypertension kan udf\u00f8res sikkert med minimale bivirkninger.<\/p>\n

Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Kemiske egenskaber<\/strong>
\nKogepunkt 809,08\u00b0C (groft sk\u00f8n)<& >densitet 1,1257 (groft sk\u00f8n)
\nbrydningsindeks 1,6700 (estimat)
\nRTECS BW2165000
\nopbevaringstemp. Opbevares p\u00e5 et m\u00f8rkt sted, Inert atmosf\u00e6re, Opbevares i fryseren, under -20\u00b0C
\nform Pulver
\npka pK1: 10,37 (25\u00b0C)
\nfarve orange
\nVandopl\u00f8selighed Opl\u00f8seligt i vand (25 mg \/ml) og 5 % eddikesyre (1 mg\/ml).
\nInChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
\nCAS DataBase Reference 4474-91-3<\/p>\n

Funktion og anvendelse af angiotensin II\/ANGIOTENSIN II, HUMAN CAS 4474-91-3<\/strong>
\nAngiotensin II er et kort peptid sammensat af 8 aminosyrer, og dets fysiologiske funktion er hovedsageligt at h\u00e6ve blodtrykket ved at tr\u00e6kke sm\u00e5 arterier sammen i hele kroppen. Derudover kan det ogs\u00e5 fremme udskillelsen af aldosteron fra binyrebarken, som virker p\u00e5 nyretubuli for at bevare natrium, vand og kalium, og dermed for\u00e5rsage en stigning i blodvolumen og blodtryk.<\/p>\n

Brug af angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3<\/strong>
\n1. Hjerte-lungeredning – endnu ikke godkendt ans\u00f8gning
\n2. Et peptid involveret i reguleringen af blodtryk
\n3. Angiotensin II er et peptidhormon, der bedst er kendt som en vasokonstriktor med centrale roller i kronisk hypertension, hjertesvigt og slagtilf\u00e6lde. Det er et octapeptid, der typisk dannes ved fjernelse af to rester fra angiotensin I af angiotensin-konverterende enzym (ACE). Angiotensin II er en ligand for mindst to forskellige receptorer, AT1 og AT2, der hver fremkalder forskellige signalveje og fysiologiske responser. Udviklingen af antagonister for specifikke angiotensin II-receptorundertyper repr\u00e6senterer et v\u00e6rdifuldt alternativ til ACE-h\u00e6mmere.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnavn: ANGIOTENSIN II, HUMAN
\nCAS: 4474-91-3
\nMF: C50H71N13O12
\nMW: 1046.2
\nEINECS: 2017-001-1
\nMol Fil: 4474-91-3 .mol<\/p>\n","protected":false},"featured_media":2161,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[404],"product_tag":[2351,2373],"class_list":{"0":"post-7412","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-blod-og-vaskulaer-peptid","7":"product_tag-angiotensin-ii-angiotensin-ii-da","8":"product_tag-human-cas-4474-91-3-for-blood-pressure-raising-da","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product\/7412","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/comments?post=7412"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media\/2161"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media?parent=7412"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_brand?post=7412"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_cat?post=7412"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_tag?post=7412"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}