{"id":8295,"date":"2021-12-16T13:20:58","date_gmt":"2021-12-16T18:20:58","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/hoejkvalitets-peptid-somatostatin-acetate-15-28-somatostatin-28-cas-38916-34-6\/"},"modified":"2021-12-16T13:20:58","modified_gmt":"2021-12-16T18:20:58","slug":"hoejkvalitets-peptid-somatostatin-acetate-15-28-somatostatin-28-cas-38916-34-6","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/da\/product\/hoejkvalitets-peptid-somatostatin-acetate-15-28-somatostatin-28-cas-38916-34-6\/","title":{"rendered":"H\u00f8jkvalitets Peptid Somatostatin Acetate\/ 15-28-Somatostatin-28 CAS 38916-34-6"},"content":{"rendered":"

H\u00f8jkvalitets Peptid Somatostatin Acetate\/ 15-28-Somatostatin-28 CAS 38916-34-6<\/strong><\/h2>\n

Produktnavn: Somatostatin Acetate\/ 15-28-Somatostatin-28
\nSynonymer: Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH ;SoMatotropin Release-inhibiting Factor, SRIF, SRIF-14;Cyclic somatostatin;SoMatostatin Acetat;V\u00c6KSTHORMONFRIGIVELSEH\u00c6MMENDE FAKTOR (MENNESKE, F\u00c5R, SVIN, ROTTE, MUS);V\u00c6KSTHORMONFRIGIVELSESH\u00c6MMENDE FAKTOR (RINEHIMNERENDE, POVINE, PORCINE MUS) 2ACOH 6H2O;H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH;H-ALA-GLY-CYS-LYS-ASN-PHE -PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (KOBLET TIL BSA)
\nCAS: 38916-34-6
\nMF: C76H104N18O19S2
\nMW: 1637.88
\nEINECS: 254-186-5
\nProduktkategorier: Aminosyrederivater;Aminosyrer og derivater;Peptid;Aminosyrer 13C, 2H, 15N;Mellemprodukter og finkemikalier;Pharmaceuticals;peptider pharm
\nMol Fil: 38916-34 .mol<\/p>\n

Somatostatin er et cyklisk 14-peptid, som f\u00f8rst blev isoleret af Guillemin i 1973 og er sandsynligvis den mest grundigt unders\u00f8gte og vigtigste af de h\u00e6mmende faktorer, der produceres af hypothaen lamus. Hovedaktiviteten af somatostatin, som er af hypothalamus oprindelse, er h\u00e6mning af frigivelsen af v\u00e6ksthormon (GH) fra hypofysen. For meget GH, som i hypofysetumorer, for\u00e5rsager akromegali, en form for gigantisme. P\u00e5 den anden side f\u00f8rer for lidt GH til dv\u00e6rgv\u00e6kst. Somatostatin er ogs\u00e5 blevet fundet i bugspytkirtlen og mave-tarmkanalen, hvor det h\u00e6mmer udskillelsen af b\u00e5de insulin og glukagon fra bugspytkirtlen samt udskillelsen af en r\u00e6kke forskellige intestinale peptider (f.eks. gastrin, sekretin, pepsin og renin). Somatostatins korte halveringstid, som er mindre end 3 minutter, har udelukket dets anvendelse som terapeutisk middel. Mange derivater af somatostatin er blevet fremstillet for at \u00f8ge dets virkningsvarighed og\/eller for at \u00f8ge dets virkningsselektivitet. Kulminationen af disse struktur-aktivitetsunders\u00f8gelser var udviklingen af octreotidacetat.<\/p>\n

Ud over hypothalamus, andre dele s\u00e5som hjernebarken, striatum, amygdala, hippocampus og rygmarven, sympatisk nerve, gastrointestinal, \u00f8-, nyre-, skjoldbruskkirtler og biskjoldbruskkirtler er udbredt i somatostatin. I hjernen og mave-tarmkanalen blev 28 aminosyrer af GHRIH28, som er en udadg\u00e5ende forl\u00e6ngelse af N-terminalen af GHRIH14, renset. Virkningen af somatostatin in vitro er kompliceret, og det kan fungere som en transmitter eller modulere i nervesystemet; somatostatin har en vis h\u00e6mmende virkning p\u00e5 gastrointestinal motilitet og sekretion af ford\u00f8jelseskanalhormoner; det h\u00e6mmer ogs\u00e5 insulin og bugspytkirtel Glukagon, renin, parathyreoideahormon og calcitonin sekretion.<\/p>\n

Somatostatin Acetate\/15-28-Somatostatin-28 CAS 38916-34-6 Kemiske egenskaber<\/strong>
\n15-28-Somatostatin-28 Kemiske egenskaber
\nKogepunkt 1970,9\u00b165,0 \u00b0C(Forudsagt)
\ndensitet 1,43\u00b10,1 g\/cm3(Forudsagt)
\nopbevaringstemp. \u221220\u00b0C
\nopl\u00f8selighed H2O: 1 mg\/mL
\npka 2,94\u00b10,70(forudsagt)
\nform pulver
\nVandopl\u00f8selighed Opl\u00f8seligt i vand (25,00\u00b0C 1,00 g\/L) , Methanol.
\nMerck 13,8788
\nBRN 6436064
\nInChIKey NHXLMOGPVYXJNR-ATOGVRKGSA-N<\/p>\n

Funktion og anvendelse af Somatostatin Acetate\/15-28-Somatostatin-28 CAS<\/strong> <& >
\n1 Det kan h\u00e6mme sekretionen af v\u00e6ksthormon, skjoldbruskkirtelstimulerende hormon, insulin, glucagon.<\/p>\n

2 Det kan h\u00e6mme mavesyresekretion stimuleret af testm\u00e5ltidet og 5-peptid gastrin og kan h\u00e6mme frigivelse af pepsin og gastrin.<\/p>\n

3 Det kan reducere den viscerale blodgennemstr\u00f8mning betydeligt, reducere portaltrykket, reducere blodgennemstr\u00f8mningen og trykket af kollateral cirkulation, reducere leverens blodgennemstr\u00f8mning.<\/p>\n

4 Det reducerer sekretionen af bugspytkirtlen og udskillelsen af tyndtarmen og galdebl\u00e6ren, reducerer enzymaktiviteten og virker beskyttende p\u00e5 bugspytkirtlens celler.<\/p>\n

5 Det kan p\u00e5virke mave-tarmkanalens optagelse og ern\u00e6ringsfunktion.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnavn: Somatostatin Acetate\/ 15-28-Somatostatin-28
\nCAS: 38916-34-6
\nMF: C76H104N18O19S2
\nMW: 1637.88
\nEINECS: 254-186-Mol
\nMol : 38916-34-6.mol<\/p>\n","protected":false},"featured_media":2119,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[531],"product_tag":[],"class_list":{"0":"post-8295","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-andre-peptider","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product\/8295","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/comments?post=8295"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media\/2119"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media?parent=8295"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_brand?post=8295"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_cat?post=8295"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_tag?post=8295"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}