{"id":8341,"date":"2021-12-16T13:24:40","date_gmt":"2021-12-16T18:24:40","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-leverer-calcitonin-laks-cas-47931-85-1-til-osteoporose\/"},"modified":"2021-12-16T13:24:40","modified_gmt":"2021-12-16T18:24:40","slug":"puya-leverer-calcitonin-laks-cas-47931-85-1-til-osteoporose","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/da\/product\/puya-leverer-calcitonin-laks-cas-47931-85-1-til-osteoporose\/","title":{"rendered":"Puya leverer Calcitonin laks CAS 47931-85-1 til osteoporose"},"content":{"rendered":"

Puya leverer Calcitonin laks CAS 47931-85-1 til osteoporose<\/strong><\/h2>\n

Produktnavn: Calcitonin laks
\nSynonymer: salmoncalcitonin-(i-32);salmoncalcitonini;tz-ct;Laks Calcitonin Acetat;Salcatonin;CALCITONIN LAKS 250 UG;Calcitoninacetat;Laksekalk: H&> Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr -Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2\uff0c(Disulfidbro: Cys1-Cys7)
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431,85
\n EINECS: 256-342-8
\nProduktkategorier: Aminosyrederivater;Peptid;Calcitonin- og CGRP-receptor
\nMol Fil: 47931-85-1.mol<\/p>\n

Calcitonin Laks er et polypeptidhormon, der udskilles af laksens ultimobranchiale kirtel. Det tilh\u00f8rer den calcitonin-lignende proteinfamilie og kan bruges til at behandle Pagets knoglesygdom, postmenopausal osteoporose (sk\u00f8re eller sk\u00f8re knogler) eller h\u00f8je niveauer af calcium i blodet (hypercalc\u00e6mi). Det ser ud til at have virkninger i det v\u00e6sentlige identiske med calcitoniner af pattedyrsoprindelse, men dets styrke pr. mg er st\u00f8rre, og det har en l\u00e6ngere virkningsvarighed. Det virker hovedsageligt ved at h\u00e6mme osteoklastisk knogleresorption, reducere serumcalcium og \u00f8ge renal udskillelse af fosfat, calcium, natriummagnesium og kalium ved at reducere tubul\u00e6r reabsorption.<\/p>\n

Naturlig calcitonin er et bioaktivt peptid, der udskilles af parathyreoideaceller hos pattedyr. eller bagg\u00e6llerne p\u00e5 hvirveldyr, og er den vigtigste regulator af calciummetabolisme i levende organismer. Laksecalcitoninacetat er et syntetisk 32-peptid, og i klinisk forskning er laksecalcitonin blevet brugt i vid udstr\u00e6kning i klinikken som et forebyggende og helbredende l\u00e6gemiddel mod osteoporose og andre metaboliske knoglesygdomme.<\/p>\n

Kemiske egenskaber ved Calcitonin laks CAS 47931-85-1<\/strong>
\nCalcitonin laks Kemiske egenskaber
\ndensitet 1,54\u00b10,1 g\/cm3(Forudsagt)
\nopbevaringstemp. \u221220\u00b0C
\nopl\u00f8selighed 0,05 M eddikesyre: 1 mg\/ml, klar, farvel\u00f8s
\nform pulver
\nVandopl\u00f8selighed Opl\u00f8selig i vand ved 1mg\/ml
\nMerck 13,1642
\nInChIKey IYTKRMFJECGBRF -LXQLIYPUSA-N
\nCAS DataBase Reference 47931-85-1(CAS DataBase Reference)<\/p>\n

Funktion og anvendelse af Calcitonin laks CAS 47931-85-1<\/strong>
\n1. Calcitonin laks kan bruges til calcitonin receptor\/cAMP assay til at vurdere tilstedev\u00e6relsen af calcitonin receptorer udtrykt af TRAP+ celler. Produktet kan ogs\u00e5 bruges som en testforbindelse til unders\u00f8gelse samt sammenligning af virkningen af calcitoningen relateret peptid (CGRP) og laksecalcitonin (sCT) p\u00e5 gastrisk slimhindebarriere hos rotter udsat for kulde + fastholdelsesstress (CRS). [sigma-aldrich]
\n2. Calcitonin, laks er et calciumregulerende hormon, der udskilles fra pattedyrs parafollikul\u00e6re skjoldbruskkirtelceller og i ikke-pattedyrarter fra den ultimobranchiale kirtel. Calcitoniner er enkeltk\u00e6dede polypeptider, der indeholder 32 aminosyrerester, som udviser hypocalc\u00e6misk og hypophosphat\u00e6misk virkning, med aminosyrestruktur, der adskiller sig fra pattedyrsart. Laksecalcitonin (salcatonin er den syntetiske analog) viser en markant anderledes sekvens end de h\u00f8jere hvirveldyr samt mere potent aktivitet. \u00c5l calcitonin (Elcatonin) har en lignende aminosyre som lakseformen, men er mere stabil end naturlige calcitoniner p\u00e5 grund af frav\u00e6ret af disulfidbroer. [Santa Cruz Bioteknologi]
\n3. Det viser hypocalc\u00e6misk og hypophosphat\u00e6misk virkning, med aminosyrestruktur, der er forskellig blandt pattedyrarter. Laksecalcitonin (salcatonin er den syntetiske analog) viser en markant anderledes sekvens end de h\u00f8jere hvirveldyr samt mere potent aktivitet. Det neds\u00e6tter blodcalcium og fosfat p\u00e5 grund af h\u00e6mning af resorption af osteoblaster og osteocytter. [alfa-aesar]
\n4. Calciumregulerende peptidhormon frigivet fra skjoldbruskkirtlen. S\u00e6nker calciumkoncentrationen i blodet og mindsker knogleresorption af osteoklaster. Anvendes til terapeutiske anvendelser ved osteoporose. Lakses calcitonin peptidsekvens adskiller sig fra pattedyr, men er mere potent.[Enzo Life Sciences, Inc.]<\/p>\n

Anvendelser af calcitonin laks CAS 47931-85-1<\/strong>
\nOsteoporose;Hypercalc\u00e6mi; Pagets sygdom; Refleks sympatisk dystrofi (algodistrofi eller Sudecks sygdom)<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnavn: Calcitonin laks
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431.85
\nEINECS: 256-342-8
\nMol Fil: 47931-85-1.mol<\/p>\n","protected":false},"featured_media":2098,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[468],"product_tag":[1304],"class_list":{"0":"post-8341","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-osteoporose-peptid","7":"product_tag-puya-supply-calcitonin-salmon-cas-47931-85-1-for-osteoporosis-da","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product\/8341","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/comments?post=8341"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media\/2098"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media?parent=8341"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_brand?post=8341"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_cat?post=8341"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_tag?post=8341"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}