{"id":8702,"date":"2021-12-17T03:00:38","date_gmt":"2021-12-17T08:00:38","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/ganirelix-acetate-cas-123246-29-7-gonadotropin-releasing-hormon-gnrh-antagonister\/"},"modified":"2021-12-17T03:00:38","modified_gmt":"2021-12-17T08:00:38","slug":"ganirelix-acetate-cas-123246-29-7-gonadotropin-releasing-hormon-gnrh-antagonister","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/da\/product\/ganirelix-acetate-cas-123246-29-7-gonadotropin-releasing-hormon-gnrh-antagonister\/","title":{"rendered":"Ganirelix Acetate CAS 123246-29-7 Gonadotropin-releasing hormon (GnRH) antagonister"},"content":{"rendered":"

Ganirelix Acetate CAS 123246-29-7 Gonadotropin-releasing hormon (GnRH) antagonister<\/strong><\/h2>\n

Produktnavn: Ganirelix Acetate
\nSynonymer: Ac-DNal-DCpa-DPal-Ser-Tyr-DHar(Et2)-Leu-Har(Et2)-Pro-DAla -NH2;Ganirelixum;ganirelix Acetate;GANIRELIX; Ganirelix Acetate USP\/EP\/BP
\nCAS: 123246-29-7
\nMF: C80H113ClN18O13
\nMW: 1570.34
\nEINECS:
\nProduktkategorier: hormoner
\nMol Fil: 123246-29 -7.mol<\/p>\n

Ganirelixacetat er en syntetisk decapeptidforbindelse, der ligner endogent gonadotropin-releasing hormon (GnRH) (ogs\u00e5 kendt som luteiniserende hormon-releasing hormon (LHRH)) og er en antagonist af GnRH, der kompetitivt antagoniserer gonadotrop GnRH-receptor, hvorved pathwayen muteres og for\u00e5rsager hurtig og reversibel h\u00e6mning af gonadotropin (luteiniserende hormon LH og follikelstimulerende hormon FSH) sekretion. Ganirelixacetat h\u00e6mmer LH-sekretion fra hypofysen mere signifikant end FSH-sekretion og reducerer derved k\u00f8nshormonproduktionen.<\/p>\n

Funktion og anvendelse af Ganirelixacetat CAS 123246-29-7<\/strong>
\nGanirelixacetat er en analog af GnRH med substitutioner ved rest 1, 2, 3, 6, 8 og 10. Det er ikke en superagonist, men er snarere et syntetisk decapeptid med h\u00f8j antagonistaktivitet og den f\u00f8rste GnRH-antagonist, der markedsf\u00f8res. Det er godkendt til undertrykkelse af LH-stigninger hos kvinder, der gennemg\u00e5r ovariehyperstimulerende fertilitetsbehandling; LH-stigninger fremmer normalt \u00e6gl\u00f8sning. M\u00e5let med dette l\u00e6gemiddel er at reducere antallet af medicindage, der er n\u00f8dvendige for at undertrykke LH-stigningen, og derved opretholde \u00e6g i \u00e6ggestokkene. In vitro fertilisering (IVF) behandlingscyklusser blev historisk initieret ved administration af leuprolidacetat for at undertrykke den for tidlige frigivelse af LH. Dette h\u00e6mmer \u00e6gl\u00f8sningen, s\u00e5 \u00e6ggene forbliver tilg\u00e6ngelige for udvinding af en fertilitetsspecialist. Til dette form\u00e5l injiceres leuprolidacetat normalt i s\u00e5 mange som 26 dage. Kliniske unders\u00f8gelser har vist, at ganirelixacetat kan lukke LH-stigningen ned p\u00e5 kun 5 dages behandling, at undertrykkelsen af LH er mere udtalt end for FSH, og at den kortere behandlingstid minimerer ubehagelige bivirkninger, s\u00e5som hedeture og hovedpine. .<\/p>\n

Det bruges hovedsageligt klinisk i kontrollerede ovariestimuleringsprotokoller til kvinder, der gennemg\u00e5r assisteret reproduktionsteknologi for at forhindre for tidlige luteiniserende hormontoppe og til behandling af fertilitetsforstyrrelser for\u00e5rsaget af denne \u00e5rsag Chemicalbook. L\u00e6gemidlet har f\u00e6rre bivirkninger, h\u00f8je graviditetsrater og korte behandlingscyklusser og har betydelige kliniske fordele sammenlignet med lignende l\u00e6gemidler.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnavn: Ganirelix Acetate
\nCAS: 123246-29-7
\nMF: C80H113ClN18O13
\nMW: 1570.34
\nProduktkategorier: hormoner
\nMol Fil: 123246-29-7.mol<\/p>\n","protected":false},"featured_media":2098,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[425],"product_tag":[1020],"class_list":{"0":"post-8702","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-urogenital-peptid","7":"product_tag-ganirelix-acetate-cas-123246-29-7-gonadotropin-releasing-hormone-gnrh-antagonists-da","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product\/8702","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/comments?post=8702"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media\/2098"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media?parent=8702"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_brand?post=8702"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_cat?post=8702"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_tag?post=8702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}