{"id":8767,"date":"2021-12-17T03:04:35","date_gmt":"2021-12-17T08:04:35","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/goserelinacetat-af-hoej-kvalitet-cas-145781-92-6-der-bruges-til-behandling-af-brystkraeft\/"},"modified":"2021-12-17T03:04:35","modified_gmt":"2021-12-17T08:04:35","slug":"goserelinacetat-af-hoej-kvalitet-cas-145781-92-6-der-bruges-til-behandling-af-brystkraeft","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/da\/product\/goserelinacetat-af-hoej-kvalitet-cas-145781-92-6-der-bruges-til-behandling-af-brystkraeft\/","title":{"rendered":"Goserelinacetat af h\u00f8j kvalitet CAS 145781-92-6, der bruges til behandling af brystkr\u00e6ft"},"content":{"rendered":"

Goserelinacetat af h\u00f8j kvalitet CAS 145781-92-6, der bruges til behandling af brystkr\u00e6ft<\/strong><\/h2>\n

Produktnavn: Goserelinacetat
\nSynonymer: PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;[(T-BU)DSER6, (AZA) )GLY10]-LH-RH;[(T-BU)DSER6, (AZA)GLY10]-LUTEINISERENDE HORMON-FLILISTEENDE HORMON;ICI-118630 acetat;GOSERELIN HCL[PYR-HIS-TRP-SER-TYR-D-SER( T-BU)-LEU-ARG-PRO-AZAGLY-NH2];1-9-luteiniserende hormonfrig\u00f8rende faktor (svin), 6-(o-(1,1-dimethylethyl)-D-serin)-, 2- (aminocarbonyl)hydrazid, acetat (salt); fertilan; GLP-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZA-GLY-NH2
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nProduktkategorier: Peptid;Pepetider;Aminosyrederivater;Mellemprodukter & Finkemikalier;Peptider;Farmaceutiske filer: 145781-92-6.mol<\/p>\n

Goserelinacetat er ligesom leuprolidacetat en syntetisk superagonist nonapeptidanalog af GnRH, der har st\u00f8rre styrke end det naturlige hormon. Bem\u00e6rk, at den indeholder D-Ser(But) og NH-NHCONH2 i stedet for henholdsvis Gly6 og Gly10-NH2. Det vil sige, at den C-terminale modifikation simpelthen har en NH, der erstatter CH2 i Gly, og ligesom den C-terminale \u00e6ndring i leuprolidacetat h\u00e6mmer dette enzymatisk nedbrydning af peptidet af postprolincarboxyamidpeptidasen.
\nGoserelinacetat er tilg\u00e6ngelig i form af en lille, solid pellet, der administreres som et SC-implantat til palliativ behandling af fremskreden, metastatisk brystkr\u00e6ft hos pr\u00e6- og perimenopausale kvinder eller p\u00e5 lignende m\u00e5de som et palliativ ved fremskreden prostatacancer. Begrundelsen for brugen af dette l\u00e6gemiddel er, som beskrevet ovenfor, dets evne som superagonist til at bringe niveauerne af \u00f8stradiol eller testosteron til n\u00e6sten kastratniveauer, og dermed bremse udviklingen af henholdsvis bryst- eller prostatacarcinom. Derudover er goserelinacetat godkendt til brug ved behandling af endometriose i op til 6 m\u00e5neder.<\/p>\n

Goserelinacetat CAS 145781-92-6 Kemiske egenskaber<\/strong>
\nSmeltepunkt >190\u00b0C (dec.)
\nopbevaring Midlertidig. -20\u00b0C
\nopl\u00f8selighed H2O: 20 mg\/mL, klar, farvel\u00f8s
\nform hvidt pulver
\nInChIKey IKDXDQDKCZPQSZ-JHYYTBFNSA-N
\nCAS DataBase Reference 145781-92-6<\/p>\n

Funktion og anvendelse Goserelinacetat CAS 145781-92-6<\/strong>
\n1. Anticancer
\n2. injicerbar gonadotropinfrig\u00f8rende hormonsuperagonist (GnRH-agonist) eller luteiniserende hormon antiproliferativ aktivitet i bryst-, prostata- og endometriecancer
\n3. Syntetisk peptidagonistanalog af LH-RH. Antineoplastisk (hormonel).<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnavn: Goserelinacetat
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nMol Fil: 145781-92-6.mol.<\/p>\n","protected":false},"featured_media":2203,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[391],"product_tag":[953],"class_list":{"0":"post-8767","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-tumor-peptid","7":"product_tag-goserelin-acetate-cas-145781-92-6-used-for-treat-breast-cancer-da","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product\/8767","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/comments?post=8767"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media\/2203"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/media?parent=8767"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_brand?post=8767"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_cat?post=8767"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/da\/wp-json\/wp\/v2\/product_tag?post=8767"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}