{"id":7298,"date":"2021-12-16T07:20:58","date_gmt":"2021-12-16T12:20:58","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/carperitide-acetate-anp-1-28-human-cas-89213-87-6-zur-behandlung-von-kongestiver-herzinsuffizienz\/"},"modified":"2021-12-16T07:20:58","modified_gmt":"2021-12-16T12:20:58","slug":"carperitide-acetate-anp-1-28-human-cas-89213-87-6-zur-behandlung-von-kongestiver-herzinsuffizienz","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/de\/product\/carperitide-acetate-anp-1-28-human-cas-89213-87-6-zur-behandlung-von-kongestiver-herzinsuffizienz\/","title":{"rendered":"Carperitide Acetate\/ ANP 1-28, HUMAN CAS 89213-87-6 Zur Behandlung von kongestiver Herzinsuffizienz"},"content":{"rendered":"

Carperitide Acetate\/ ANP 1-28, HUMAN CAS 89213-87-6 Zur Behandlung von kongestiver Herzinsuffizienz<\/strong><\/h2>\n

Produktname: Carperitidacetat\/ANP 1-28, HUMAN
\nSequenz: H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg- Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH\uff0c(Disulfidbr\u00fccke: Cys-Cys)
\nSynonyme: ATRIAL NATRIURETIC PEPTIDE HUMAN;SER- LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER- PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDE BRIDGE CYS7-CYS23.;Carperitide Acetat, Carperitida;Atrial Natriuretic Peptide (1-28) (human) (Trifluoracetate Salt);ahANF, Carperitid;H-Ser- Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe- Arg-Tyr-OH;Atrial natriureticpeptide-28 (human) (9CI);Atrial Natriuretic Factor (1-28) (human) \u03b1hANF, Carperitide
\nCAS: 89213-87-6
\nMF: C127H203N45O39S3
\n MW: 3080.44
\nEINECS: 686-482-9
\nProduktkategorien: Peptid
\nMol Datei: 89213-87-6.mol<\/p>\n

Carperitide ist ein 28 Aminos\u00e4uren langes Polypeptid mit einem stabilen sekund\u00e4ren Struktur und ist ein Cir kultivierendes Hormon, das als Vasodilatator und Diuretikum wirkt. In der klinischen Praxis ist die durch Carperitid als Hauptwirkstoff induzierte Vasodilatation auf die Bindung an ANP (atrial natriuretic polypeptid)-Rezeptoren in der glatten Gef\u00e4\u00dfmuskulatur zur\u00fcckzuf\u00fchren, die durch die Erh\u00f6hung der Aktivit\u00e4t der Guanylatzyklase erreicht wird, was auf eine Verringerung der kardialen Vor- und Nachlast hindeutet. <\/p>\n

Carperitide ist das durch rekombinante Technologie hergestellte \u03b1-humane atriale natriuretische Peptid (\u03b1-hANP). Es wurde in Japan zur Behandlung von akuter kongestiver Herzinsuffizienz (CHF) eingef\u00fchrt. Bei Hunden mit CHF reduzierte Carperitid signifikant den erh\u00f6hten linksventrikul\u00e4ren enddiastolischen Druck und den Index des myokardialen Sauerstoffverbrauchs (systolischer Blutdruck x Herzfrequenz). In einer klinischen Studie war Carperitid wirksam bei der Verbesserung der H\u00e4modynamik und der Symptome bei 60 % der Patienten mit akuter CHF. Es wurde berichtet, dass Carperitid gut vertragen wird und klinisch keine signifikanten Nebenwirkungen hat. Bei Patienten mit chronischer Herzinsuffizienz wurde \u00fcber eine positive Wirkung auf die H\u00e4modynamik berichtet. Carperitid befindet sich auch in klinischen Studien zur Aufrechterhaltung des Blutdrucks w\u00e4hrend chirurgischer Eingriffe.<\/p>\n

Anwendung<\/strong>
\nBehandlung dekompensierter kongestiver Herzinsuffizienz.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktname: Carperitide Acetate\/ ANP 1-28, HUMAN
\nCAS: 89213-87-6
\nMF: C127H203N45O39S3
\nMW: 3080.44
\nEINECS: 686-482-9
\nMol Datei: 89213-87-6.mol<\/p>\n","protected":false},"featured_media":2291,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[496],"product_tag":[2454,2476],"class_list":{"0":"post-7298","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptid-fuer-das-herz-kreislauf-system","7":"product_tag-carperitide-acetate-anp-1-28-de","8":"product_tag-human-cas-89213-87-6-for-treatment-of-congestive-heart-failure-de","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product\/7298","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/comments?post=7298"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/media\/2291"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/media?parent=7298"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_brand?post=7298"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_cat?post=7298"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_tag?post=7298"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}