{"id":7781,"date":"2021-12-16T10:33:23","date_gmt":"2021-12-16T15:33:23","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-cilengitide-cas-188968-51-6-fuer-laborforschung\/"},"modified":"2021-12-16T10:33:23","modified_gmt":"2021-12-16T15:33:23","slug":"puya-supply-cilengitide-cas-188968-51-6-fuer-laborforschung","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/de\/product\/puya-supply-cilengitide-cas-188968-51-6-fuer-laborforschung\/","title":{"rendered":"Puya Supply Cilengitide CAS 188968-51-6 f\u00fcr Laborforschung"},"content":{"rendered":"

Puya Supply Cilengitide CAS 188968-51-6 f\u00fcr Laborforschung<\/strong><\/h2>\n

Produktname: Cilengitide
\nSequenz: Cyclo(Arg-Gly-Asp-D-Phe-N-Me-Val)
\nSynonyme: 2-[(2S,5R,8S,11S)-5- Benzyl-11-[3-(diaminomethylidenamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2 -yl]essigs\u00e4ure;Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl);Cilengitide(EMD121974,NSC-707544);Cilengitide;C(RGDf-Me-V);EMD 121974;EMD-121974;EMD121974;CS-1500;CS-2674
\nCAS: 188968-51-6
\nMF: C27H40N8O7
\nMW: 588.66
\nEINECS:
\nProduktkategorien: Inhibitoren< &>Mol Datei: 188968-51-6.mol<\/p>\n

Cilengitide ist ein zyklisches Peptid, das die RGD-Sequenz enth\u00e4lt. Das Peptid basiert in vivo auf dem \u03b1v\u03b23-Integrinliganden und wurde durch eine Kombination aus Zyklisierung, r\u00e4umlichem Screening und Methylierungsscanning mit hoher Affinit\u00e4t und Selektivit\u00e4t f\u00fcr \u03b1v\u03b23-Integrine erhalten. Tests haben gezeigt, dass das Peptid nicht nur das Wachstum von Melanomen und Glioblastomen besser hemmen kann, sondern in Kombination mit einer Strahlentherapie auch die Heilungsrate anderer Tumoren wie Plattenepithelkarzinomen im Kopf-Hals-Bereich verbessern kann, was eine gute Marktaussicht und Potenzial hat . Bei der Peptidsynthese wurde Cilengitide durch die Kombination der Festphasen-Peptidsynthesetechnologie mit der Fl\u00fcssigphasen-Peptidsynthesetechnologie hergestellt.<\/p>\n

Cilengitide CAS 188968-51-6 Chemische Eigenschaften<\/strong>
\nDichte 1,41\u00b10,1 g\/cm3 (vorhergesagt)< &>Lagertemp. -20\u00b0C
\nFormpulver
\npka 4,01\u00b10,10(vorhergesagt)
\nFarbe wei\u00df bis beige<\/p>\n

Verwendungen von Cilengitide CAS 188968-51-6<\/strong>
\nAngiogenese-Inhibitor.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktname: Cilengitide
\nCAS: 188968-51-6
\nMF: C27H40N8O7
\nMW: 588.66
\nMol Datei: 188968-51-6.mol<\/p>\n","protected":false},"featured_media":2207,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[396],"product_tag":[2051],"class_list":{"0":"post-7781","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-tumor-peptid-de","7":"product_tag-puya-supply-cilengitide-cas-188968-51-6-for-lab-research-de","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product\/7781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/comments?post=7781"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/media\/2207"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/media?parent=7781"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_brand?post=7781"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_cat?post=7781"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_tag?post=7781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}