{"id":8134,"date":"2021-12-16T12:19:54","date_gmt":"2021-12-16T17:19:54","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/vapreotidacetat-rc-160-cas-103222-11-3-behandlung-fuer-akute-oesophagusvarizenblutung\/"},"modified":"2021-12-16T12:19:54","modified_gmt":"2021-12-16T17:19:54","slug":"vapreotidacetat-rc-160-cas-103222-11-3-behandlung-fuer-akute-oesophagusvarizenblutung","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/de\/product\/vapreotidacetat-rc-160-cas-103222-11-3-behandlung-fuer-akute-oesophagusvarizenblutung\/","title":{"rendered":"Vapreotidacetat\/RC 160 CAS 103222-11-3 Behandlung f\u00fcr akute \u00d6sophagusvarizenblutung"},"content":{"rendered":"

Vapreotidacetat\/RC 160 CAS 103222-11-3 Behandlung f\u00fcr akute \u00d6sophagusvarizenblutung<\/strong><\/h2>\n

Produktname: VAPREOTIDE
\nSynonyme: D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 (Disulfidbr\u00fccke Cys2-Cys7);HD-Phe-Cys-Tyr-D -Trp-Lys-Val-Cys-Trp-NH2;D-Phe-Cys-Trp-D-Trp-Lys-Val-Cys-Trp-CONH2(Disulfid Cys2-Cys7);Vapreotid, RC-160;RC-160 ;VAPREOTID;D-PHE-CYS-TYR-D-TRP-LYS-VAL-CYS-TRP-NH2;FCYWKVCW-NH2
\nCAS: 103222-11-3
\nMF: C57H70N12O9S2
\nMW: 1131.37
\nEINECS:
\nProduktkategorien: Somatostatin-Rezeptor
\nMol File: 103222-11-3.mol<\/p>\n

H3Pharma hat die weltweite Forschungsentwicklungs- und kommerzielle Lizenz f\u00fcr Vaptan von Debiopharm in der Schweiz erworben. 2001 berichtete das New England Journal of Medicine \u00fcber die Formulierung mit sofortiger Wirkstofffreisetzung, die von Chemicalbook klinisch getestet und f\u00fcr den fr\u00fchen Einsatz bei der Behandlung akuter Speiser\u00f6hrenentz\u00fcndungen nachgewiesen wurde .<\/p>\n

Vapreotidacetat\/ RC 160 CAS 103222-11-3 Chemische Eigenschaften<\/strong>
\nSiedepunkt 1540.9\u00b165,0 \u00b0C (vorhergesagt)
\nDichte 1,40\u00b10,1 g\/cm3 (vorhergesagt)
\nLagerung temp. \u221220\u00b0C
\npka 9,90\u00b10,15(vorhergesagt)<\/p>\n

Funktion und Anwendung von Vapreotid Acetate\/ RC 160 CAS 103222-11-3<\/strong>
\n1. Die Formulierung von Sanvar, einem Somatostatin-Analogon mit sofortiger Freisetzung , wird zur Behandlung von akuten \u00d6sophagusvarizenblutungen (EVB) verwendet.
\n2.Sanvar wird vor endoskopischen Eingriffen verwendet, um Blutungen zu kontrollieren und eine erneute Blutung w\u00e4hrend der kritischen f\u00fcnf Tage nach dem Einsetzen der Blutung zu verhindern. EVB ist eine lebensbedrohliche Erkrankung und die Sterblichkeitsrate ist in den ersten sechs Wochen nach der Blutung hoch (ca. 15 bis 25 %). EVB ist die Ursache f\u00fcr etwa 70 % der gastrointestinalen Blutungen bei Patienten mit Leberzirrhose.
\n 3. Sanvar (Vapreotidacetat) ist ein synthetisches Octapeptid-Analogon des nat\u00fcrlich vorkommenden Somatostatin-Hormons. Es hat \u00e4hnliche pharmakologische Eigenschaften wie natives Somatostatin, weist jedoch eine l\u00e4ngere Wirkdauer auf. Es ist das einzige Somatostatin-Analogon, das in einer placebokontrollierten klinischen Studie statistisch signifikante Vorteile bei der fr\u00fchen Behandlung von EVB in Verbindung mit einer endoskopischen Therapie gezeigt hat (Cal\u00e8s et al. New England Journal of Medicine, 2001). Eine Blutstillung mit \u00dcberlebenszeit nach f\u00fcnf Tagen wurde mit Sanvar h\u00e4ufiger (p=0,021) als mit Placebo erreicht. Zus\u00e4tzlich<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktname: VAPREOTIDE
\nCAS: 103222-11-3
\nMF: C57H70N12O9S2
\nMW: 1131.37
\nMol Datei: 103222-11-3.mol<\/p>\n","protected":false},"featured_media":2123,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[522],"product_tag":[1530],"class_list":{"0":"post-8134","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-andere-peptide","7":"product_tag-vapreotide-acetate-rc-160-cas-103222-11-3-treatment-for-acute-esophageal-variceal-bleeding-de","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product\/8134","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/comments?post=8134"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/media\/2123"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/media?parent=8134"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_brand?post=8134"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_cat?post=8134"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/de\/wp-json\/wp\/v2\/product_tag?post=8134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}