{"id":7740,"date":"2021-12-16T10:31:00","date_gmt":"2021-12-16T15:31:00","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-cilengitide-cas-188968-51-6-para-investigacion-de-laboratorio\/"},"modified":"2021-12-16T10:31:00","modified_gmt":"2021-12-16T15:31:00","slug":"puya-supply-cilengitide-cas-188968-51-6-para-investigacion-de-laboratorio","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/es\/product\/puya-supply-cilengitide-cas-188968-51-6-para-investigacion-de-laboratorio\/","title":{"rendered":"Puya Supply Cilengitide CAS 188968-51-6 para investigaci\u00f3n de laboratorio"},"content":{"rendered":"

Puya Supply Cilengitide CAS 188968-51-6 para investigaci\u00f3n de laboratorio<\/strong><\/h2>\n

Nombre del producto: cilengitide
\n Secuencia: ciclo (Arg-Gly-Asp-D-Phe-N-Me-Val)
\n Sin\u00f3nimos: 2 – [(2S, 5R, 8S, 11S) -5- bencil-11- [3- (diaminometilidenamino) propil] -7-metil-3,6,9,12,15-pentaoxo-8-propan-2-il-1,4,7,10,13-pentazaciclopentadec-2 -il] \u00e1cido ac\u00e9tico; ciclo (L-arginilglicil-L-aspartil-D-fenilalanil-N-metil-L-valilo); Cilengitida (EMD121974, NSC-707544); Cilengitida; C (RGDf-Me-V); EMD 121974; EMD-121974; EMD121974; CS-1500; CS-2674
\n CAS: 188968-51-6
\n MF: C27H40N8O7
\n MW: 588.66
\n EINECS:
\n Categor\u00edas de productos: Inhibidores < &> Mol File: 188968-51-6.mol <\/p>\n

Cilengitide es un p\u00e9ptido c\u00edclico que contiene la secuencia RGD. El p\u00e9ptido se basa en el ligando de la integrina \u03b1v \u03b23 in vivo y se obtuvo mediante una combinaci\u00f3n de ciclaci\u00f3n, exploraci\u00f3n espacial y exploraci\u00f3n por metilaci\u00f3n, con alta afinidad y selectividad por las integrinas \u03b1v \u03b23. Las pruebas han demostrado que el p\u00e9ptido no solo puede inhibir mejor el crecimiento de melanoma y glioblastoma, sino que tambi\u00e9n puede mejorar la tasa de curaci\u00f3n de otros tumores como los tumores de c\u00e9lulas escamosas de cabeza y cuello en combinaci\u00f3n con radioterapia, que tiene una buena perspectiva de mercado y potencial. . En la s\u00edntesis de p\u00e9ptidos, Cilengitide se produjo combinando tecnolog\u00eda de s\u00edntesis de p\u00e9ptidos en fase s\u00f3lida con tecnolog\u00eda de s\u00edntesis de p\u00e9ptidos en fase l\u00edquida. <\/p>\n

Cilengitide CAS 188968-51-6 Propiedades qu\u00edmicas<\/strong>
\n densidad 1,41 \u00b1 0,1 g \/ cm3 (predicho) < &> temperatura de almacenamiento -20 \u00b0 C
\n forma polvo
\n pka 4,01 \u00b1 0,10 (previsto)
\n color blanco a beige <\/p>\n

Usos de cilengitida CAS 188968-51-6<\/strong>
\n Inhibidor de la angiog\u00e9nesis.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nombre del producto: cilengitide
\n CAS: 188968-51-6
\n MF: C27H40N8O7
\n MW: 588.66
\n Mol Archivo: 188968-51-6.mol<\/p>\n","protected":false},"featured_media":2216,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[385],"product_tag":[2040],"class_list":{"0":"post-7740","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptido-antitumoral","7":"product_tag-puya-supply-cilengitide-cas-188968-51-6-for-lab-research-es","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product\/7740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/comments?post=7740"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/media\/2216"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/media?parent=7740"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_brand?post=7740"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_cat?post=7740"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_tag?post=7740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}