{"id":8101,"date":"2021-12-16T12:18:39","date_gmt":"2021-12-16T17:18:39","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/invitacion-del-acetato-cas-107452-89-1-de-ziconotide-para-la-neuralgia-posherpetica-y-el-dolor-del-cancer\/"},"modified":"2021-12-16T12:18:39","modified_gmt":"2021-12-16T17:18:39","slug":"invitacion-del-acetato-cas-107452-89-1-de-ziconotide-para-la-neuralgia-posherpetica-y-el-dolor-del-cancer","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/es\/product\/invitacion-del-acetato-cas-107452-89-1-de-ziconotide-para-la-neuralgia-posherpetica-y-el-dolor-del-cancer\/","title":{"rendered":"Invitaci\u00f3n del acetato CAS 107452-89-1 de Ziconotide para la neuralgia posherp\u00e9tica y el dolor del c\u00e1ncer"},"content":{"rendered":"

Invitaci\u00f3n del acetato CAS 107452-89-1 de Ziconotide para la neuralgia posherp\u00e9tica y el dolor del c\u00e1ncer<\/strong><\/h2>\n

Nombre del producto: Acetato de ziconotida
\n Sin\u00f3nimos: OMEGA-CONOTOXIN MVIIA; OMEGA-CGTX MVII A; ACETATO DE ZICONOTIDO; snx111; H-CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG -LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2; H-CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS -SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY-LYS-CYS-NH2 (PUENTE DE DISULFURO: 1-16, 8-20 Y 15 -25); CYS-LYS-GLY-LYS-GLY-ALA-LYS-CYS-SER-ARG-LEU-MET-TYR-ASP-CYS-CYS-THR-GLY-SER-CYS-ARG-SER-GLY- LYS-CYS-NH2; CKGKGAKCSRLMYDCCTGSCRSGKC-NH2 (PUENTE DE DISULFURO: 1-16,8-20 Y 15-25)
\n CAS: 107452-89-1
\n MF: C102H172N36O32S7
\n MW: 2639,13 <& > EINECS:
\n Categor\u00edas de productos: P\u00e9ptido
\n Mol Archivo: 107452-89-1.mol <\/p>\n

Ziconotide (Prialt) es un compuesto de toxina pept\u00eddica de 25 amino\u00e1cidos y tres enlaces disulfuro derivado del sur Caracol marino del Pac\u00edfico Conusmagus. Es el primer agente neuroterap\u00e9utico novedoso: bloqueador de los canales de calcio de tipo N (NCCB). Act\u00faa selectivamente sobre los canales de calcio de Chemicalbook electrosensibles de tipo N en las ramas terminales dendr\u00edticas y axonales, inhibiendo as\u00ed los est\u00edmulos aferentes de la lesi\u00f3n inicial. Est\u00e1 indicado para pacientes con dolor cr\u00f3nico severo que requieren tratamiento intratecal y que son intolerantes o tienen poca eficacia de otros tratamientos analg\u00e9sicos (p. Ej., Aplicaci\u00f3n de analg\u00e9sicos sist\u00e9micos o morfina intratecal). La ziconotida intratecal se puede utilizar para tratar la neuralgia posherp\u00e9tica, el dolor del miembro fantasma, el dolor neurop\u00e1tico relacionado con el VIH, el dolor por c\u00e1ncer refractario y el dolor posquir\u00fargico. <\/p>\n

Acetato de ziconotida CAS 107452-89-1 Propiedades qu\u00edmicas<\/strong>
\n densidad 1,60 \u00b1 0,1 g \/ cm3 (previsto)
\n temperatura de almacenamiento. -20 \u00b0 C
\n InChIKey BPKIMPVREBSLAJ-QTBYCLKRSA-N <\/p>\n

Usos de acetato de ziconotida CAS 107452-89-1<\/strong>
\n Ligando para estudios de uni\u00f3n de canales de calcio sensibles al voltaje. <\/p>\n

Ziconotida ( SNX-111; Prialt), tambi\u00e9n llamado ziconotida intratecal (ITZ) debido a su v\u00eda de administraci\u00f3n, es un agente analg\u00e9sico at\u00edpico para la mejora del dolor severo y cr\u00f3nico. Derivado de Conus magus, un caracol cono, es la forma sint\u00e9tica de un p\u00e9ptido \u03c9-conotoxina. [1] Es 1.000 veces m\u00e1s potente que la morfina. <\/p>\n

Este producto es adecuado para pacientes con dolor cr\u00f3nico severo que requieren tratamiento intratecal y que son intolerantes o tienen poca eficacia a otros tratamientos analg\u00e9sicos (como la aplicaci\u00f3n de analg\u00e9sicos sist\u00e9micos o inyecci\u00f3n intratecal de morfina, etc.). <\/p>\n

Funci\u00f3n y aplicaci\u00f3n de acetato de ziconotida CAS 107452-89-1<\/strong>
\n 1. Eficacia analg\u00e9sica Ziconotida es adecuada para pacientes con dolor cr\u00f3nico que no pueden tolerar o no responden a otros tratamientos, incluida la medicaci\u00f3n sist\u00e9mica, el tratamiento adyuvante de la inyecci\u00f3n intratecal de morfina. La inyecci\u00f3n intratecal de ziconotida tiene eficacia analg\u00e9sica cl\u00ednica y estad\u00edsticamente significativa en pacientes con c\u00e1ncer o SIDA. <\/p>\n

2. Protecci\u00f3n de la m\u00e9dula espinal Isquemia de la m\u00e9dula espinal a corto plazo Cuando se da\u00f1an las neuronas de la m\u00e9dula espinal, se activa la v\u00eda del calcio electrosensible de tipo N. La ziconotida puede proporcionar neuroprotecci\u00f3n y analgesia durante la cirug\u00eda a\u00f3rtica.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nombre del producto: Acetato de ziconotida
\n CAS: 107452-89-1
\n MF: C102H172N36O32S7
\n MW: 2639.13
\n Mol Archivo: 107452-89-1.mol<\/p>\n","protected":false},"featured_media":2216,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[523],"product_tag":[1584],"class_list":{"0":"post-8101","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-otros-peptidos","7":"product_tag-ziconotide-acetate-cas-107452-89-1-treat-for-postherpetic-neuralgia-and-cancer-pain-es","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product\/8101","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/comments?post=8101"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/media\/2216"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/media?parent=8101"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_brand?post=8101"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_cat?post=8101"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_tag?post=8101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}