{"id":8956,"date":"2021-12-17T03:40:00","date_gmt":"2021-12-17T08:40:00","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/linaclotide-cas-851199-59-2-para-tratar-el-sindrome-del-intestino-irritable-estrenido-ibs-c-y-el-estrenimiento-idiopatico-cronico-cic\/"},"modified":"2021-12-17T03:40:00","modified_gmt":"2021-12-17T08:40:00","slug":"linaclotide-cas-851199-59-2-para-tratar-el-sindrome-del-intestino-irritable-estrenido-ibs-c-y-el-estrenimiento-idiopatico-cronico-cic","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/es\/product\/linaclotide-cas-851199-59-2-para-tratar-el-sindrome-del-intestino-irritable-estrenido-ibs-c-y-el-estrenimiento-idiopatico-cronico-cic\/","title":{"rendered":"Linaclotide CAS 851199-59-2 para tratar el s\u00edndrome del intestino irritable estre\u00f1ido (IBS-C) y el estre\u00f1imiento idiop\u00e1tico cr\u00f3nico (CIC)"},"content":{"rendered":"

Linaclotide CAS 851199-59-2 para tratar el s\u00edndrome del intestino irritable estre\u00f1ido (IBS-C) y el estre\u00f1imiento idiop\u00e1tico cr\u00f3nico (CIC)<\/strong><\/h2>\n

Nombre del producto: Linaclotide
\n Sin\u00f3nimos: Linacllotide; Linaclotide; Linaelotide Acetate; Linaelotide; CY-14; Liclotide; Argpessin; L-Tyrosine, L-cysteinyl-L-cysteinyl-L-\u03b1-glutamyl-L-tyrosyl -L-cisteinil-L-cisteinil-L-asparaginil-L-prolil-L-alanil-L-cisteinil-L-treonilglicil-L-cisteinil-, c\u00edclico (1 \u2192 6), (2 \u2192 10), (5 \u2192 13) -tris (disulfuro)
\n CAS: 851199-59-2
\n MF: C59H79N15O21S6
\n MW: 1526,74
\n EINECS:
\n Categor\u00edas de productos: Inhibitors
\n Mol File: 851199-59 -2.mol <\/p>\n

Especificaci\u00f3n de Linaclotide<\/strong> <\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Contenido de la prueba<\/td>\n Especificaciones<\/td>\n<\/tr>\n
Apariencia<\/td>\n Polvo cristalino blanco o casi blanco<\/td>\n<\/tr>\n
Identidad por HPLC<\/td>\n La reacci\u00f3n es la misma con la sustancia de referencia.<\/td>\n<\/tr>\n
Composici\u00f3n de amino\u00e1cidos<\/td>\n \u00b1 20% del te\u00f3rico<\/td>\n<\/tr>\n
Pureza (HPLC)<\/td>\n \u2265 98,0%<\/td>\n<\/tr>\n
Sustancia relacionada (por HPLC)<\/td>\n Impurezas totales (%) \u2264 2.0%
\n Impureza individual m\u00e1s grande (%) \u2264 1.0%<\/td>\n<\/tr>\n
Contenido de acetato (por HPLC)<\/td>\n \u226415%<\/td>\n<\/tr>\n
Contenido de agua (por HPLC)<\/td>\n \u22645.0%<\/td>\n<\/tr>\n
Endotoxinas bacterianas<\/td>\n \u22645 UI \/ mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Funci\u00f3n y aplicaci\u00f3n de linaclotida<\/strong>
\n linaclotide es un agonista pept\u00eddico de la guanilato ciclasa 2C. <\/p>\n

Este compuesto reduce la activaci\u00f3n de las neuronas sensoriales del colon, reduciendo el dolor; y activa las neuronas motoras del colon, lo que aumenta la contracci\u00f3n del m\u00fasculo liso y, por lo tanto, promueve los movimientos intestinales. <\/p>\n

Fue aprobado por la FDA en agosto de 2012 para el tratamiento del estre\u00f1imiento idiop\u00e1tico cr\u00f3nico y el s\u00edndrome del intestino irritable con estre\u00f1imiento predominante (IBS-C ) en adultos.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nombre del producto: Linaclotide
\n CAS: 851199-59-2
\n MF: C59H79N15O21S6
\n MW: 1526.74
\n EINECS:
\n Categor\u00edas de productos: Inhibitors
\n Mol File: 851199-59-2. mol<\/p>\n","protected":false},"featured_media":2132,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[459],"product_tag":[],"class_list":{"0":"post-8956","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptido-del-sistema-gastrointestinal","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product\/8956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/comments?post=8956"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/media\/2132"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/media?parent=8956"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_brand?post=8956"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_cat?post=8956"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/es\/wp-json\/wp\/v2\/product_tag?post=8956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}