{"id":7296,"date":"2021-12-16T07:20:58","date_gmt":"2021-12-16T12:20:58","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/carperitide-acetate-anp-1-28-human-cas-89213-87-6-kongestiivisen-sydamen-vajaatoiminnan-hoitoon\/"},"modified":"2021-12-16T07:20:58","modified_gmt":"2021-12-16T12:20:58","slug":"carperitide-acetate-anp-1-28-human-cas-89213-87-6-kongestiivisen-sydamen-vajaatoiminnan-hoitoon","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fi\/product\/carperitide-acetate-anp-1-28-human-cas-89213-87-6-kongestiivisen-sydamen-vajaatoiminnan-hoitoon\/","title":{"rendered":"Carperitide Acetate\/ANP 1-28, HUMAN CAS 89213-87-6 Kongestiivisen syd\u00e4men vajaatoiminnan hoitoon"},"content":{"rendered":"

Carperitide Acetate\/ANP 1-28, HUMAN CAS 89213-87-6 Kongestiivisen syd\u00e4men vajaatoiminnan hoitoon<\/strong><\/h2>\n

Tuotteen nimi: Carperitide Acetate\/ANP 1-28, HUMAN
\nSekvenssi: H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg- Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH\uff0c(disulfidisilta: Cys-Cys)
\nSynonyymit: ATRIAL NATRIUREETIC PEPTIDE HUMAN;SER- LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER- PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDISILTA CYS7-CYS23.;Carperitide-asetaatti, carperitida;Eteisen natriureettinen peptidi (1-28) (ihminen) (trifluoriasetaattisuola);ahANH-SCarerperi-tidi; Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe- Arg-Tyr-OH; Eteisen natriureettinen peptidi-28 (ihminen) (9CI); Eteisen natriureettinen tekij\u00e4 (1-28) (ihminen) \u03b1hANF, Carperitide
\nCAS: 89213-87-6
\nMF: C127H203N45&O39S3 MW: 3080.44
\nEINECS: 686-482-9
\nTuoteluokat: peptidi
\nMol File: 89213-87-6.mol<\/p>\n

Carperitide on 28 aminohapon polypeptidi, jolla on vakaa sekundaarinen rakenne ja on cir Kulatorinen hormoni, joka toimii verisuonia laajentavana ja diureettisena aineena. Kliinisess\u00e4 k\u00e4yt\u00e4nn\u00f6ss\u00e4 karperitidin p\u00e4\u00e4ainesosana aiheuttama verisuonten laajeneminen johtuu sitoutumisesta ANP-reseptoreihin (atrial natriuretic polypeptide) verisuonten sile\u00e4ss\u00e4 lihaksessa, mik\u00e4 saavutetaan lis\u00e4\u00e4m\u00e4ll\u00e4 guanylaattisyklaasin aktiivisuutta, mik\u00e4 viittaa syd\u00e4men esi- ja j\u00e4lkikuormituksen v\u00e4henemiseen. <\/p>\n

Carperitide on yhdistelm\u00e4-DNA-tekniikalla tuotettu \u03b1-ihmisen eteisen natriureettinen peptidi (\u03b1-hANP). Se otettiin k\u00e4ytt\u00f6\u00f6n Japanissa akuutin syd\u00e4men vajaatoiminnan (CHF) hoitona. Koirilla, joilla oli syd\u00e4men vajaatoiminta, karperitidi alensi merkitt\u00e4v\u00e4sti kohonnutta vasemman kammion loppudiastolista painetta ja syd\u00e4nlihaksen hapenkulutusindeksi\u00e4 (systolinen verenpaine x syke). Kliinisess\u00e4 tutkimuksessa karperitidi paransi tehokkaasti hemodynamiikkaa ja oireita 60 %:lla potilaista, joilla oli akuutti CHF. Karperitidin raportoitiin olevan hyvin siedetty ilman merkitt\u00e4vi\u00e4 kliinisi\u00e4 haittavaikutuksia. Kroonista syd\u00e4men vajaatoimintaa sairastavilla potilailla on raportoitu olevan suotuisa vaikutus hemodynamiikkaan. Carperitide on my\u00f6s kliinisiss\u00e4 tutkimuksissa verenpaineen yll\u00e4pit\u00e4miseksi kirurgisten leikkausten aikana.<\/p>\n

K\u00e4ytt\u00f6kohde<\/strong>
\nDekompensoituneen syd\u00e4men vajaatoiminnan hoito.<\/p>\n","protected":false},"excerpt":{"rendered":"

Tuotteen nimi: Carperitide Acetate\/ ANP 1-28, HUMAN
\nCAS: 89213-87-6
\nMF: C127H203N45O39S3
\nMW: 3080.44
\nEINECS: 686-482-9
\nMol Tiedosto: 89213-87-6.mol<\/p>\n","protected":false},"featured_media":2289,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[494],"product_tag":[2452,2474],"class_list":{"0":"post-7296","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-sydan-ja-verisuonijarjestelman-peptidi","7":"product_tag-carperitide-acetate-anp-1-28-fi","8":"product_tag-human-cas-89213-87-6-for-treatment-of-congestive-heart-failure-fi","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product\/7296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/comments?post=7296"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media\/2289"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media?parent=7296"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_brand?post=7296"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_cat?post=7296"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_tag?post=7296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}