{"id":8275,"date":"2021-12-16T13:19:32","date_gmt":"2021-12-16T18:19:32","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/korkealaatuinen-peptidi-somatostatiiniasetaatti-15-28-somatostatin-28-cas-38916-34-6\/"},"modified":"2021-12-16T13:19:32","modified_gmt":"2021-12-16T18:19:32","slug":"korkealaatuinen-peptidi-somatostatiiniasetaatti-15-28-somatostatin-28-cas-38916-34-6","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fi\/product\/korkealaatuinen-peptidi-somatostatiiniasetaatti-15-28-somatostatin-28-cas-38916-34-6\/","title":{"rendered":"Korkealaatuinen peptidi somatostatiiniasetaatti\/ 15-28-Somatostatin-28 CAS 38916-34-6"},"content":{"rendered":"

Korkealaatuinen peptidi somatostatiiniasetaatti\/ 15-28-Somatostatin-28 CAS 38916-34-6<\/strong><\/h2>\n

Tuotteen nimi: Somatostatin Acetate\/ 15-28-Somatostatin-28
\nSynonyymit: Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH ;SoMatotropiinin vapautumista est\u00e4v\u00e4 tekij\u00e4, SRIF, SRIF-14;Syklinen somatostatiini;SoMatostatiiniasetaatti;KASVUHORMONEIN VAPAUTTAMISTA EST\u00c4V\u00c4 TEKIJ\u00c4 (ihminen, lammas, sika, rotta, hiiri);kasvuhormonien vapauttaja HIIRI) 2ACOH 6H2O;H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH;H-ALA-GLY-CYS-LYS-ASN-PHE -PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (KYTKETTY BSA:han)
\nCAS: 38916-34-6
\nMF: C76H104N18O19S2
\nMW: 1637,88
\nEINECS: 254-186-5
\nTuoteluokat: Aminohappojohdannaiset; Aminohapot ja johdannaiset; Peptidit; Aminohapot 13C, 2H, 15N; V\u00e4lituotteet ja hienokemikaalit; L\u00e4\u00e4keteollisuus; peptidit pharm
\nMol6 6-38-9 Tiedosto: .mol<\/p>\n

Somatostatiini on syklinen 14-peptidi, jonka Guillemin eristi ensimm\u00e4isen kerran vuonna 1973 ja joka on luultavasti perusteellisemmin tutkittu ja t\u00e4rkein hypothan tuottamista inhiboivista tekij\u00f6ist\u00e4 lamus. Somatostatiinin, joka on per\u00e4isin hypotalamuksesta, p\u00e4\u00e4asiallinen vaikutus on kasvuhormonin (GH) vapautumisen est\u00e4minen aivolis\u00e4kkeen etuosasta. Liiallinen kasvuhormoni, kuten aivolis\u00e4kkeen kasvaimissa, aiheuttaa akromegaliaa, er\u00e4\u00e4nlaista j\u00e4ttim\u00e4isyytt\u00e4. Toisaalta liian v\u00e4h\u00e4n GH:a johtaa k\u00e4\u00e4pi\u00f6isyyteen. Somatostatiinia on l\u00f6ydetty my\u00f6s haimasta ja ruoansulatuskanavasta, miss\u00e4 se est\u00e4\u00e4 sek\u00e4 insuliinin ett\u00e4 glukagonin erittymist\u00e4 haimasta sek\u00e4 erilaisten suoliston peptidien (esim. gastriini, sekretiini, pepsiini ja reniini) erittymist\u00e4. Somatostatiinin lyhyt puoliintumisaika, joka on alle 3 minuuttia, on est\u00e4nyt sen k\u00e4yt\u00f6n terapeuttisena aineena. Monet somatostatiinin johdannaiset on valmistettu pident\u00e4m\u00e4\u00e4n sen vaikutusaikaa ja\/tai parantamaan sen toiminnan selektiivisyytt\u00e4. N\u00e4iden rakenne-aktiivisuustutkimusten huipentuma oli oktreotidiasetaatin kehitt\u00e4minen.<\/p>\n

Hypotalamuksen lis\u00e4ksi muita osia, kuten aivokuori, striatum, amygdala, hippokampus ja selk\u00e4ydin, sympaattinen hermo, maha-suolikanava, saareke, munuainen, kilpirauhanen ja lis\u00e4kilpirauhanen ovat laajalti jakaantuneet somatostatiiniin. Aivoissa ja maha-suolikanavassa puhdistettiin 28 aminohappoa GHRIH28:sta, joka on GHRIH14:n N-p\u00e4\u00e4n ulosp\u00e4in jatke. Somatostatiinin vaikutus in vitro on monimutkainen, ja se voi toimia v\u00e4litt\u00e4j\u00e4n\u00e4 tai moduloida hermostoa; somatostatiinilla on tietty est\u00e4v\u00e4 vaikutus maha-suolikanavan motiliteettiin ja ruoansulatuskanavan hormonien eritykseen; se my\u00f6s est\u00e4\u00e4 insuliinin ja haiman glukagonin, reniinin, lis\u00e4kilpirauhashormonin ja kalsitoniinin erityst\u00e4.<\/p>\n

Somatostatin Acetate\/15-28-Somatostatin-28 CAS 38916-34-6 Kemialliset ominaisuudet<\/strong>
\n15-28-Somatostatin-28 Kemialliset ominaisuudet
\nKiehumispiste 1970,9\u00b165,0 \u00b0C (ennustettu)
\ntiheys 1,43\u00b10,1 g\/cm3 (ennustettu)
\nvarastointil\u00e4mp\u00f6tila. \u221220\u00b0C
\nliukoisuus H2O: 1 mg\/mL
\npka 2,94\u00b10,70(ennustettu)
\njauhemuoto
\nVesiliukoisuus Vesiliukoinen (25,00\u00b0C 1,00 g\/L) , Metanoli.
\nMerck 13,8788
\nBRN 6436064
\nInChIKey NHXLMOGPVYXJNR-ATOGVRKGSA-N<\/p>\n

Somatostatiiniasetaatin\/15-28-Somatostatin-28 CAS:n toiminta<\/strong> ja k\u00e4ytt\u00f6 >
\n1 Se voi est\u00e4\u00e4 kasvuhormonin, kilpirauhasta stimuloivan hormonin, insuliinin, glukagonin erittymist\u00e4.<\/p>\n

2 Se voi est\u00e4\u00e4 testiaterian ja 5-peptidi-gastriinin stimuloimaa mahahapon erityst\u00e4 sek\u00e4 est\u00e4\u00e4 pepsiinin ja gastriinin vapautuminen.<\/p>\n

3 Se voi v\u00e4hent\u00e4\u00e4 merkitt\u00e4v\u00e4sti viskeraalista verenkiertoa, v\u00e4hent\u00e4\u00e4 portaalipainetta, v\u00e4hent\u00e4\u00e4 verenkiertoa ja sivuverenkierron painetta, v\u00e4hent\u00e4\u00e4 maksan verenkiertoa.<\/p>\n

4 Se v\u00e4hent\u00e4\u00e4 erityst\u00e4. haiman ja ohutsuolen ja sappirakon erityst\u00e4 v\u00e4hent\u00e4v\u00e4t entsyymiaktiivisuutta ja suojaavat haiman soluja.<\/p>\n

5 Se voi vaikuttaa ruoansulatuskanavan imeytymiseen ja ravitsemustoimintaan.<\/p>\n","protected":false},"excerpt":{"rendered":"

Tuotteen nimi: Somatostatin Acetate\/ 15-28-Somatostatin-28
\nCAS: 38916-34-6
\nMF: C76H104N18O19S2
\nMW: 1637.88
\nEINECS: 254-186-5
\nM File : 38916-34-6.mol<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[],"product_tag":[],"class_list":{"0":"post-8275","1":"product","2":"type-product","3":"status-publish","5":"desktop-align-left","6":"tablet-align-left","7":"mobile-align-left","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product\/8275","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/comments?post=8275"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media?parent=8275"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_brand?post=8275"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_cat?post=8275"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_tag?post=8275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}