{"id":8349,"date":"2021-12-16T13:24:43","date_gmt":"2021-12-16T18:24:43","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-kalsitoniinilohi-cas-47931-85-1-osteoporoosiin\/"},"modified":"2021-12-16T13:24:43","modified_gmt":"2021-12-16T18:24:43","slug":"puya-supply-kalsitoniinilohi-cas-47931-85-1-osteoporoosiin","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fi\/product\/puya-supply-kalsitoniinilohi-cas-47931-85-1-osteoporoosiin\/","title":{"rendered":"Puya Supply Kalsitoniinilohi CAS 47931-85-1 Osteoporoosiin"},"content":{"rendered":"

Puya Supply Kalsitoniinilohi CAS 47931-85-1 Osteoporoosiin<\/strong><\/h2>\n

Tuotteen nimi: Kalsitoniinilohi
\nSynonyymit: salmoncalcitonin-(i-32);salmoncalcitonini;tz-ct;Salmon Calcitonin Acetate;Salcatonin;CALCITONIN SALMON 250 UG;Calcitonin Acetate;Calcitonin Acetate;Salmon Calcium Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr -Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2\uff0c(disulfidisilta: Cys1-Cys7)
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431,85
\n EINECS: 256-342-8
\nTuoteluokat: Aminohappojohdannaiset; Peptidi; Kalsitoniini ja CGRP-reseptori
\nMol Tiedosto: 47931-85-1.mol<\/p>\n

Kalsitoniini Lohi on polypeptidihormoni, jota eritt\u00e4\u00e4 lohen ultimobraankiaalinen rauhanen. Se kuuluu kalsitoniinin kaltaisten proteiinien perheeseen ja sit\u00e4 voidaan k\u00e4ytt\u00e4\u00e4 Pagetin luutaudin, postmenopausaalisen osteoporoosin (hauraat tai hauraat luut) tai korkean veren kalsiumpitoisuuden (hyperkalsemia) hoitoon. Sen vaikutukset n\u00e4ytt\u00e4v\u00e4t olevan olennaisesti identtisi\u00e4 nis\u00e4k\u00e4sper\u00e4isten kalsitoniinien kanssa, mutta sen teho\/mg on suurempi ja sen vaikutusaika on pidempi. Se toimii p\u00e4\u00e4asiassa est\u00e4m\u00e4ll\u00e4 osteoklastien luun resorptiota, v\u00e4hent\u00e4m\u00e4ll\u00e4 seerumin kalsiumia ja lis\u00e4\u00e4m\u00e4ll\u00e4 fosfaatin, kalsiumin, natriummagnesiumin ja kaliumin erittymist\u00e4 munuaisten kautta v\u00e4hent\u00e4m\u00e4ll\u00e4 tubulaarista reabsorptiota.<\/p>\n

Luonnollinen kalsitoniini on bioaktiivinen peptidi, jota nis\u00e4kk\u00e4iden lis\u00e4kilpirauhassolut eritt\u00e4v\u00e4t. tai selk\u00e4rankaisten takakidukset, ja se on p\u00e4\u00e4asiallinen kalsiumin aineenvaihdunnan s\u00e4\u00e4telij\u00e4 el\u00e4viss\u00e4 organismeissa. Lohen kalsitoniiniasetaatti on synteettinen 32-peptidi, ja kliinisiss\u00e4 tutkimuksissa lohen kalsitoniinia on k\u00e4ytetty laajalti klinikalla osteoporoosin ja muiden metabolisten luusairauksien ehk\u00e4isev\u00e4n\u00e4 ja parantavana l\u00e4\u00e4kkeen\u00e4.<\/p>\n

Kalsitoniinilohen CAS:n kemialliset ominaisuudet 47931-85-1<\/strong>
\nKalsitoniinilohi Kemialliset ominaisuudet
\ntiheys 1,54\u00b10,1 g\/cm3(ennustettu)
\nvarastointil\u00e4mp\u00f6tila. \u221220\u00b0C
\nliukoisuus 0,05 M etikkahappo: 1 mg\/ml, kirkas, v\u00e4rit\u00f6n
\njauhemainen
\nVesiliukoisuus Liukenee veteen 1 mg\/ml
\nMerck 13,1642
\nInChIKey IYTKRMFJECGBRFRF -LXQLIYPUSA-N
\nCAS-tietokannan viite 47931-85-1(CAS-tietokannan viite)<\/p>\n

Kalsitoniinilohen CAS 47931-85-1 toiminta ja sovellus<\/strong>
\n1. Kalsitoniinilohia voidaan k\u00e4ytt\u00e4\u00e4 kalsitoniinireseptori\/cAMP-m\u00e4\u00e4rityksess\u00e4 TRAP+-solujen ilment\u00e4mien kalsitoniinireseptorien l\u00e4sn\u00e4olon arvioimiseksi. Tuotetta voidaan k\u00e4ytt\u00e4\u00e4 my\u00f6s testiyhdisteen\u00e4 tutkittaessa ja vertailtaessa kalsitoniinigeeniin liittyv\u00e4n peptidin (CGRP) ja lohen kalsitoniini (sCT) mahalaukun limakalvon esteess\u00e4 rotilla, jotka ovat altistuneet kylm\u00e4lle + rajoitusstressille (CRS). [sigma-aldrich]
\n2. Kalsitoniini, lohi, on kalsiumia s\u00e4\u00e4telev\u00e4 hormoni, joka erittyy nis\u00e4kk\u00e4\u00e4n kilpirauhasen parafollikulaarisista soluista ja ei-nis\u00e4k\u00e4slajeilla ultimobrankiaalisesta rauhasesta. Kalsitoniinit ovat yksiketjuisia polypeptidej\u00e4, jotka sis\u00e4lt\u00e4v\u00e4t 32 aminohappot\u00e4hdett\u00e4 ja joilla on hypokalseemista ja hypofosfateemista vaikutusta ja joiden aminohapporakenne vaihtelee eri nis\u00e4k\u00e4slajeissa. Lohen kalsitoniinilla (salkatoniini on synteettinen analogi) on selv\u00e4sti erilainen sekvenssi kuin korkeampien selk\u00e4rankaisten, ja sen aktiivisuus on tehokkaampi. Ankeriaan kalsitoniinissa (Elcatonin) on samanlainen aminohappo kuin lohen muodossa, mutta se on vakaampi kuin luonnolliset kalsitoniinit, koska siin\u00e4 ei ole disulfidisiltoja. [Santa Cruzin biotekniikka]
\n3. Sill\u00e4 on hypokalseemista ja hypofosfateemista vaikutusta, ja aminohapporakenne vaihtelee nis\u00e4k\u00e4slajeittain. Lohen kalsitoniinilla (salkatoniini on synteettinen analogi) on selv\u00e4sti erilainen sekvenssi kuin korkeampien selk\u00e4rankaisten, ja sen aktiivisuus on tehokkaampi. Se v\u00e4hent\u00e4\u00e4 veren kalsiumia ja fosfaattia, koska se est\u00e4\u00e4 osteoblastien ja osteosyyttien resorptiota. [alfa-aesar]
\n4. Kilpirauhasesta vapautuva kalsiumia s\u00e4\u00e4telev\u00e4 peptidihormoni. Alentaa veren kalsiumpitoisuutta ja v\u00e4hent\u00e4\u00e4 osteoklastien aiheuttamaa luun resorptiota. K\u00e4ytet\u00e4\u00e4n osteoporoosin hoitoon. Lohen kalsitoniinipeptidisekvenssi eroaa nis\u00e4kk\u00e4iden sekvenssist\u00e4, mutta on tehokkaampi.[Enzo Life Sciences, Inc.]<\/p>\n

Kalsitoniinilohen k\u00e4ytt\u00f6tarkoitukset CAS 47931-85-1<\/strong>
\nOsteoporoosi;Hyperkalsemia; Pagetin tauti; Refleksi sympaattinen dystrofia (algodistrofia tai Sudeckin tauti)<\/p>\n","protected":false},"excerpt":{"rendered":"

Tuotenimi: Kalsitoniinilohi
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431.85
\nEINECS: 256-342-8
\nMol File: 47931-85-1.<\/p>\n","protected":false},"featured_media":2100,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[471],"product_tag":[1311],"class_list":{"0":"post-8349","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-osteoporoosin-peptidi","7":"product_tag-puya-supply-calcitonin-salmon-cas-47931-85-1-for-osteoporosis-fi","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product\/8349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/comments?post=8349"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media\/2100"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media?parent=8349"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_brand?post=8349"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_cat?post=8349"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_tag?post=8349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}