{"id":8769,"date":"2021-12-17T03:04:35","date_gmt":"2021-12-17T08:04:35","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/korkealaatuinen-gosereliiniasetaatti-cas-145781-92-6-jota-kaytetaan-rintasyovan-hoitoon\/"},"modified":"2021-12-17T03:04:35","modified_gmt":"2021-12-17T08:04:35","slug":"korkealaatuinen-gosereliiniasetaatti-cas-145781-92-6-jota-kaytetaan-rintasyovan-hoitoon","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fi\/product\/korkealaatuinen-gosereliiniasetaatti-cas-145781-92-6-jota-kaytetaan-rintasyovan-hoitoon\/","title":{"rendered":"Korkealaatuinen gosereliiniasetaatti CAS 145781-92-6, jota k\u00e4ytet\u00e4\u00e4n rintasy\u00f6v\u00e4n hoitoon"},"content":{"rendered":"

Korkealaatuinen gosereliiniasetaatti CAS 145781-92-6, jota k\u00e4ytet\u00e4\u00e4n rintasy\u00f6v\u00e4n hoitoon<\/strong><\/h2>\n

Tuotteen nimi: Gosereliiniasetaatti
\nSynonyymit: PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;[(T-BU)DSER6, (AZA) )GLY10]-LH-RH;[(T-BU)DSER6, (AZA)GLY10]-LUTEINOIVA HORMONIA vapauttava hormoni;ICI-118630-asetaatti;GOSERELIN HCL[PYR-HIS-TRP-SER-TYR-D-SER( T-BU)-LEU-ARG-PRO-AZAGLY-NH2]; 1-9-luteinisoivaa hormonia vapauttava tekij\u00e4 (siat), 6-(o-(1,1-dimetyylietyyli)-D-seriini)-, 2- (aminokarbonyyli)hydratsidi, asetaatti (suola); Fertilan;GLP-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZA-GLY-NH2
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nTuoteluokat: Peptidit; Pepetidit; Aminohappojohdannaiset; V\u00e4lituotteet ja hienokemikaalit; Peptidit: Pharmaa 145781-92-6.mol<\/p>\n

Gosereliiniasetaatti, kuten leuprolidiasetaatti, on GnRH:n synteettinen superagonisti nonapeptidianalogi, jolla on suurempi teho kuin luonnollisella hormonilla. Huomaa, ett\u00e4 se sis\u00e4lt\u00e4\u00e4 D-Ser(But) ja NH-NHCONH2 Gly6:n ja Gly10-NH2:n tilalla, vastaavasti. Toisin sanoen C-terminaalisessa modifikaatiossa on yksinkertaisesti NH, joka korvaa Gly:n CH2:n, ja kuten C-terminaalinen muutos leuprolidiasetaatissa, t\u00e4m\u00e4 est\u00e4\u00e4 peptidin entsymaattista hajoamista postproliinikarboksiamidipeptidaasin vaikutuksesta.
\nGosereliiniasetaattia on saatavana pieni, kiinte\u00e4 pelletti, joka annetaan SC-implanttina pitk\u00e4lle edenneen, metastaattisen rintasy\u00f6v\u00e4n palliatiiviseen hoitoon pre- ja perimenopausaalisilla naisilla tai vastaavasti palliatiivisena l\u00e4\u00e4kkeen\u00e4 edenneen eturauhassy\u00f6v\u00e4n hoidossa. T\u00e4m\u00e4n l\u00e4\u00e4kkeen k\u00e4yt\u00f6n perusteena on, kuten edell\u00e4 on kuvattu, sen kyky superagonistina saattaa estradiolin tai testosteronin tasot l\u00e4helle kastraattitasoja, mik\u00e4 hidastaa rinta- tai eturauhassy\u00f6v\u00e4n etenemist\u00e4, vastaavasti. Lis\u00e4ksi gosereliiniasetaatti on hyv\u00e4ksytty k\u00e4ytett\u00e4v\u00e4ksi endometrioosin hoidossa enint\u00e4\u00e4n 6 kuukauden ajan.<\/p>\n

Gosereliiniasetaatti CAS 145781-92-6 Kemialliset ominaisuudet<\/strong>
\nSulamispiste >190\u00b0C (hajoaa)
\nvarastointi temp. -20\u00b0C
\nliukoisuus H2O: 20 mg\/ml, kirkas, v\u00e4rit\u00f6n
\nmuodossa valkoinen jauhe
\nInChIKey IKDXDQDKCZPQSZ-JHYYTBFNSA-N
\nCAS-tietokannan viite 145781-92-6<\/p>\n

Toiminta ja sovellus Gosereliiniasetaatti CAS 145781-92-6<\/strong>
\n1. Sy\u00f6v\u00e4n vastainen
\n2. ruiskeena annettava gonadotropiinia vapauttavan hormonin superagonisti (GnRH-agonisti) tai luteinisoivan hormonin antiproliferatiivinen aktiivisuus rinta-, eturauhas- ja kohdun limakalvosy\u00f6viss\u00e4
\n3. LH-RH:n synteettinen peptidiagonistianalogi. Antineoplastinen (hormonaalinen).<\/p>\n","protected":false},"excerpt":{"rendered":"

Tuotteen nimi: Gosereliiniasetaatti
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nMol File: 145781-92-6.mol<\/p>\n","protected":false},"featured_media":2205,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[388],"product_tag":[955],"class_list":{"0":"post-8769","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-kasvaimen-vastainen-peptidi","7":"product_tag-goserelin-acetate-cas-145781-92-6-used-for-treat-breast-cancer-fi","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product\/8769","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/comments?post=8769"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media\/2205"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media?parent=8769"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_brand?post=8769"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_cat?post=8769"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_tag?post=8769"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}