{"id":8948,"date":"2021-12-17T03:39:57","date_gmt":"2021-12-17T08:39:57","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/linaclotide-cas-851199-59-2-ummetuksen-artyvan-suolen-oireyhtyman-ibs-c-ja-kroonisen-idiopaattisen-ummetuksen-cic-hoitoon\/"},"modified":"2021-12-17T03:39:57","modified_gmt":"2021-12-17T08:39:57","slug":"linaclotide-cas-851199-59-2-ummetuksen-artyvan-suolen-oireyhtyman-ibs-c-ja-kroonisen-idiopaattisen-ummetuksen-cic-hoitoon","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fi\/product\/linaclotide-cas-851199-59-2-ummetuksen-artyvan-suolen-oireyhtyman-ibs-c-ja-kroonisen-idiopaattisen-ummetuksen-cic-hoitoon\/","title":{"rendered":"Linaclotide CAS 851199-59-2 Ummetuksen \u00e4rtyv\u00e4n suolen oireyhtym\u00e4n (IBS-C) ja kroonisen idiopaattisen ummetuksen (CIC) hoitoon"},"content":{"rendered":"

Linaclotide CAS 851199-59-2 Ummetuksen \u00e4rtyv\u00e4n suolen oireyhtym\u00e4n (IBS-C) ja kroonisen idiopaattisen ummetuksen (CIC) hoitoon<\/strong><\/h2>\n

Tuotteen nimi: Linaclotide
\nSynonyymit: Linacllotide;Linaclotide;Linaelotide Acetate;Linaelotide;CY-14;Liclotide;Argpessin;L-tyrosiini, L-kysteinyyli-L-kysteinyyli-L-\u03b1-glutamyyli-L-tyrosyyli -L-kysteinyyli-L-kysteinyyli-L-asparaginyyli-L-prolyyli-L-alanyyli-L-kysteinyyli-L-treonyyliglysyyli-L-kysteinyyli-, syklinen (1 \u2192 6), (2 \u2192 10), (5 \u2192 13)-tris(disulfidi)
\nCAS: 851199-59-2
\nMF: C59H79N15O21S6
\nMW: 1526,74
\nEINECS:
\nTuoteluokat: Inhibiittorit
\nMol File: 8591 -2.mol<\/p>\n

Linaclotiden erittely<\/strong> <\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Testauksen sis\u00e4lt\u00f6<\/td>\n Tekniset tiedot<\/td>\n<\/tr>\n
Ulkomuoto<\/td>\n Valkoinen tai l\u00e4hes valkoinen kiteinen jauhe<\/td>\n<\/tr>\n
Identiteetti HPLC:ll\u00e4<\/td>\n Reaktio on sama vertailuaineen kanssa<\/td>\n<\/tr>\n
Aminohappokoostumus<\/td>\n \u00b120 % teoreettisesta<\/td>\n<\/tr>\n
Puhtaus (HPLC)<\/td>\n \u2265 98,0 %<\/td>\n<\/tr>\n
Aiheeseen liittyv\u00e4 aine (HPLC:ll\u00e4)<\/td>\n Ep\u00e4puhtauksien kokonaism\u00e4\u00e4r\u00e4 (%)\u2264 2,0 %
\nSuurin yksitt\u00e4inen ep\u00e4puhtaus (%)\u2264 1,0 %<\/td>\n<\/tr>\n
Asetaattipitoisuus (HPLC:ll\u00e4)<\/td>\n \u226415 %<\/td>\n<\/tr>\n
Vesipitoisuus (HPLC:ll\u00e4)<\/td>\n \u22645,0 %<\/td>\n<\/tr>\n
Bakteerien endotoksiinit<\/td>\n \u22645 IU\/mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Linaklotidin toiminta ja k\u00e4ytt\u00f6<\/strong>
\nLinaklotidi on guanylaattisyklaasin 2C peptidiagonisti.<\/p>\n

T\u00e4m\u00e4 yhdiste v\u00e4hent\u00e4\u00e4 paksusuolen sensoristen hermosolujen aktivaatiota ja v\u00e4hent\u00e4\u00e4 kipua; ja aktivoi paksusuolen motorisia neuroneja, mik\u00e4 lis\u00e4\u00e4 sile\u00e4n lihaksen supistumista ja edist\u00e4\u00e4 siten suolen toimintaa.<\/p>\n

FDA hyv\u00e4ksyi sen elokuussa 2012 kroonisen idiopaattisen ummetuksen ja ummetusta hallitsevan \u00e4rtyv\u00e4n suolen oireyhtym\u00e4n (IBS-C) hoitoon. ) aikuisilla.<\/p>\n","protected":false},"excerpt":{"rendered":"

Tuotenimi: Linaclotide
\nCAS: 851199-59-2
\nMF: C59H79N15O21S6
\nMW: 1526.74
\nEINECS:
\nTuoteluokat: Inhibiittorit
\nMol File: 851199-59. mol<\/p>\n","protected":false},"featured_media":2121,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[449],"product_tag":[],"class_list":{"0":"post-8948","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-ruoansulatuskanavan-peptidi","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product\/8948","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/comments?post=8948"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media\/2121"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/media?parent=8948"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_brand?post=8948"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_cat?post=8948"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fi\/wp-json\/wp\/v2\/product_tag?post=8948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}