{"id":7299,"date":"2021-12-16T07:20:59","date_gmt":"2021-12-16T12:20:59","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/acetate-de-carperitide-anp-1-28-human-cas-89213-87-6-pour-le-traitement-de-linsuffisance-cardiaque-congestive\/"},"modified":"2021-12-16T07:20:59","modified_gmt":"2021-12-16T12:20:59","slug":"acetate-de-carperitide-anp-1-28-human-cas-89213-87-6-pour-le-traitement-de-linsuffisance-cardiaque-congestive","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fr\/product\/acetate-de-carperitide-anp-1-28-human-cas-89213-87-6-pour-le-traitement-de-linsuffisance-cardiaque-congestive\/","title":{"rendered":"Ac\u00e9tate de carp\u00e9ritide\/ANP 1-28, HUMAN CAS 89213-87-6 Pour le traitement de l'insuffisance cardiaque congestive"},"content":{"rendered":"

Ac\u00e9tate de carp\u00e9ritide\/ANP 1-28, HUMAN CAS 89213-87-6 Pour le traitement de l'insuffisance cardiaque congestive<\/strong><\/h2>\n

Nom du produit\u00a0: Ac\u00e9tate de carp\u00e9ritide\/ANP 1-28, HUMAN
\nSequence\uff1a H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg- Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH\uff0c(Pont disulfure : Cys-Cys)
\nSynonymes : ATRIAL NATRIURETIC PEPTIDE HUMAIN;SER- LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER- PHE-ARG-TYR[SLRRSSCFGGR-MET\u00a0: O-DRIGAQSGLGCNSFRY]DISULFIDE BRIDGE CYS7-CYS23. Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe- Arg-Tyr-OH;Atrial natriureticpeptide-28 (humain) (9CI);Atrial Natriuretic Factor (1-28) (humain) \u03b1hANF, Carperitide
\nCAS\u00a0: 89213-87-6
\nMF\u00a0: C127H203N45O39S3
\n MW : 3080.44
\nEINECS : 686-482-9
\nCat\u00e9gories de produit : peptide
\nMol File : 89213-87-6.mol<\/p>\n

Carperitide est un polypeptide de 28 acides amin\u00e9s avec un secondaire stable structure et est un cir hormone culatoire qui agit comme vasodilatateur et diur\u00e9tique. En pratique clinique, la vasodilatation induite par le carp\u00e9ritide en tant qu'ingr\u00e9dient principal est due \u00e0 la liaison aux r\u00e9cepteurs ANP (polypeptide natriur\u00e9tique auriculaire) dans le muscle lisse vasculaire, ce qui est obtenu en augmentant l'activit\u00e9 de la guanylate cyclase, sugg\u00e9rant une r\u00e9duction de la pr\u00e9 et postcharge cardiaque. <\/p>\n

Le carp\u00e9ritide est le peptide natriur\u00e9tique auriculaire -humain (\u03b1-hANP) produit par la technologie recombinante. Il a \u00e9t\u00e9 introduit au Japon comme traitement de l'insuffisance cardiaque congestive aigu\u00eb (ICC). Chez les chiens atteints d'ICC, le carp\u00e9ritide a r\u00e9duit de mani\u00e8re significative la pression t\u00e9l\u00e9diastolique ventriculaire gauche \u00e9lev\u00e9e et l'indice de consommation d'oxyg\u00e8ne du myocarde (pression art\u00e9rielle systolique x fr\u00e9quence cardiaque). Dans un essai clinique, le carp\u00e9ritide s'est av\u00e9r\u00e9 efficace pour am\u00e9liorer l'h\u00e9modynamique et les sympt\u00f4mes chez 60\u00a0% des patients atteints d'ICC aigu\u00eb. Il a \u00e9t\u00e9 rapport\u00e9 que le carp\u00e9ritide \u00e9tait bien tol\u00e9r\u00e9 sans effets ind\u00e9sirables significatifs sur le plan clinique. Un effet b\u00e9n\u00e9fique sur l'h\u00e9modynamique a \u00e9t\u00e9 rapport\u00e9 chez les patients atteints d'insuffisance cardiaque chronique. Le carp\u00e9ritide fait \u00e9galement l'objet d'essais cliniques pour le maintien de la pression art\u00e9rielle pendant les op\u00e9rations chirurgicales.<\/p>\n

Application<\/strong>
\nTraitement de l'insuffisance cardiaque congestive d\u00e9compens\u00e9e.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nom du produit\u00a0: Ac\u00e9tate de carp\u00e9ritide\/ANP 1-28, HUMAN
\nCAS\u00a0: 89213-87-6
\nMF\u00a0: C127H203N45O39S3
\nMW\u00a0: 3080.44
\nEINECS\u00a0: 686-482-9
\nMol File\u00a0: 89213-87-6.mol<\/p>\n","protected":false},"featured_media":2290,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[497],"product_tag":[2455,2477],"class_list":{"0":"post-7299","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptide-du-systeme-cardiovasculaire","7":"product_tag-carperitide-acetate-anp-1-28-fr","8":"product_tag-human-cas-89213-87-6-for-treatment-of-congestive-heart-failure-fr","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product\/7299","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/comments?post=7299"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media\/2290"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media?parent=7299"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_brand?post=7299"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_cat?post=7299"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_tag?post=7299"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}