{"id":7423,"date":"2021-12-16T07:59:19","date_gmt":"2021-12-16T12:59:19","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/angiotensine-ii-angiotensin-ii-cas-humain-4474-91-3-pour-laugmentation-de-la-pression-arterielle\/"},"modified":"2021-12-16T07:59:19","modified_gmt":"2021-12-16T12:59:19","slug":"angiotensine-ii-angiotensin-ii-cas-humain-4474-91-3-pour-laugmentation-de-la-pression-arterielle","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fr\/product\/angiotensine-ii-angiotensin-ii-cas-humain-4474-91-3-pour-laugmentation-de-la-pression-arterielle\/","title":{"rendered":"Angiotensine II\/ANGIOTENSIN II, CAS HUMAIN 4474-91-3 pour l'augmentation de la pression art\u00e9rielle"},"content":{"rendered":"

Angiotensine II\/ANGIOTENSIN II, CAS HUMAIN 4474-91-3 pour l'augmentation de la pression art\u00e9rielle<\/strong><\/h2>\n

Nom du produit\u00a0: ANGIOTENSIN II, HUMAN
\nS\u00e9quence\u00a0: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
\nSynonymes\u00a0: DRVYIHPF;[ILE5]-ANGIOTENSIN 2;HYPERTENSION II HUMAIN;L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE;H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH;FLUORESCEIN-NHCS-NH-ASP-ARG- VAL-TYR-ILE-HIS-PRO-PHE-OH;ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O;ANGIOTENSIN II, HUMAIN
\nCAS\u00a0: 4474-91-3<& >MF\u00a0: C50H71N13O12
\nMW\u00a0:\u00a01046.2
\nEINECS\u00a0:\u00a02017-001-1
\nCat\u00e9gories de produits\u00a0: Angiotensine;peptide
\nFichier Mol\u00a0:\u00a04474-91-3.mol<\/p>\n

Il est On sait que les tissus tumoraux, y compris les ganglions lymphatiques m\u00e9tastatiques, sont compos\u00e9s de nouveaux vaisseaux en croissance qui manquent d'autor\u00e9gulation du flux sanguin et ne sont influenc\u00e9s que secondairement par les vaisseaux somatiques qui r\u00e9pondent. L'angiotensine humaine II (AT II). un vasopresseur, a \u00e9t\u00e9 introduit au Japon pour am\u00e9liorer l'efficacit\u00e9 de la chimioth\u00e9rapie syst\u00e9mique. Chez les patients atteints de divers cancers avanc\u00e9s, une perfusion iv d'AT II pour atteindre une pression art\u00e9rielle moyenne de 1,5 fois la valeur initiale (mais pas plus de 150 mm Hg) suivie d'une injection en bolus d'agents cytotoxiques conventionnels augmente le flux sanguin de 5 \u00e0 7 fois dans les tissus tumoraux et par cons\u00e9quent, augmente l'administration du m\u00e9dicament au tissu cible, ce qui entra\u00eene des effets chimioth\u00e9rapeutiques am\u00e9lior\u00e9s. Ce r\u00e9gime de chimioth\u00e9rapie pour l'hypertension induite peut \u00eatre effectu\u00e9 en toute s\u00e9curit\u00e9 avec des effets secondaires minimes.<\/p>\n

Angiotensine II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Propri\u00e9t\u00e9s chimiques<\/strong>
\nPoint d'\u00e9bullition 809,08\u00b0C (estimation approximative)<& >densit\u00e9 1,1257 (estimation approximative)
\nindice de r\u00e9fraction 1,6700 (estimation)
\nRTECS BW2165000
\ntemp. Conserver dans un endroit sombre,Atmosph\u00e8re inerte,Conserver au cong\u00e9lateur, \u00e0 moins de -20\u00b0C
\nforme Poudre
\npka pK1\u00a0: 10,37 (25\u00b0C)
\ncouleur orange
\nSolubilit\u00e9 dans l'eau Soluble dans l'eau (25 mg \/ml) et 5% d'acide ac\u00e9tique (1 mg\/ml).
\nInChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
\nCAS DataBase Reference 4474-91-3<\/p>\n

Fonction et application de l'angiotensine II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3<\/strong>
\n L'angiotensine II est un peptide court compos\u00e9 de 8 acides amin\u00e9s, et sa fonction physiologique est principalement d'augmenter la tension art\u00e9rielle en resserrant les petites art\u00e8res dans tout le corps. De plus, elle peut \u00e9galement favoriser la s\u00e9cr\u00e9tion d'aldost\u00e9rone par le cortex surr\u00e9nalien, qui agit sur les tubules r\u00e9naux pour conserver le sodium, l'eau et le potassium, provoquant ainsi une augmentation du volume sanguin et de la pression art\u00e9rielle.<\/p>\n

Utilisations de l'angiotensine II\/ ANGIOTENSINE II, HUMAINE CAS 4474-91-3<\/strong>
\n1. R\u00e9animation cardio-pulmonaire – pas encore une demande approuv\u00e9e
\n2. Un peptide impliqu\u00e9 dans la r\u00e9gulation de la pression art\u00e9rielle
\n3. L'angiotensine II est une hormone peptidique connue comme un vasoconstricteur avec un r\u00f4le central dans l'hypertension chronique, l'insuffisance cardiaque et les accidents vasculaires c\u00e9r\u00e9braux. Il s'agit d'un octapeptide g\u00e9n\u00e9ralement g\u00e9n\u00e9r\u00e9 par l'\u00e9limination de deux r\u00e9sidus de l'angiotensine I par l'enzyme de conversion de l'angiotensine (ACE). L'angiotensine II est un ligand pour au moins deux r\u00e9cepteurs distincts, AT1 et AT2, chacun \u00e9voquant des voies de signalisation et des r\u00e9ponses physiologiques distinctes. Le d\u00e9veloppement d'antagonistes pour des sous-types sp\u00e9cifiques de r\u00e9cepteurs de l'angiotensine II repr\u00e9sente une alternative int\u00e9ressante aux inhibiteurs de l'ECA.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nom du produit : ANGIOTENSIN II, HUMAIN
\nCAS : 4474-91-3
\nMF : C50H71N13O12
\nMW : 1046.2
\nEINECS : 2017-001-1
\nMol File : 4474-91-3 .mol<\/p>\n","protected":false},"featured_media":2164,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[408],"product_tag":[2359,2381],"class_list":{"0":"post-7423","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-sang-et-peptide-vasculaire","7":"product_tag-angiotensin-ii-angiotensin-ii-fr","8":"product_tag-human-cas-4474-91-3-for-blood-pressure-raising-fr","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product\/7423","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/comments?post=7423"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media\/2164"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media?parent=7423"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_brand?post=7423"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_cat?post=7423"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_tag?post=7423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}