{"id":8191,"date":"2021-12-16T12:23:29","date_gmt":"2021-12-16T17:23:29","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/thymosin-1-thymosin-%ce%b11-acetatethymosin-alpha-1-cas-162304-98-7-pour-traiter-lhepatite-b-chronique-et-stimuler-le-systeme-immunitaire\/"},"modified":"2021-12-16T12:23:29","modified_gmt":"2021-12-16T17:23:29","slug":"thymosin-1-thymosin-%ce%b11-acetatethymosin-alpha-1-cas-162304-98-7-pour-traiter-lhepatite-b-chronique-et-stimuler-le-systeme-immunitaire","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fr\/product\/thymosin-1-thymosin-%ce%b11-acetatethymosin-alpha-1-cas-162304-98-7-pour-traiter-lhepatite-b-chronique-et-stimuler-le-systeme-immunitaire\/","title":{"rendered":"Thymosin 1\/ Thymosin \u03b11\/AcetateThymosin Alpha 1 CAS 162304-98-7 Pour Traiter l'h\u00e9patite B chronique et stimuler le syst\u00e8me immunitaire"},"content":{"rendered":"

Thymosin 1\/ Thymosin \u03b11\/AcetateThymosin Alpha 1 CAS 162304-98-7 Pour Traiter l'h\u00e9patite B chronique et stimuler le syst\u00e8me immunitaire<\/strong><\/h2>\n

Nom du produit\u00a0: Thymosine \u03b11
\nS\u00e9quence\u00a0: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu -Lys-Glu-Val-Glu-Glu-Ala-Glu-Ala-Glu-Asn-OH
\nSynonymes : THYMOSIN ALPHA 1;THYMOSIN ALPHA1 BOVINE;THYMOSIN APHA 1;ZADAXIN;Thymosine \u03b11 Ac\u00e9tate;Thymosine Thymalate de sel; Sel d'ac\u00e9tate;Thymosine \u03b1 1 Ac\u00e9tate (Thymalfasine)
\nCAS\u00a0: 62304-98-7
\nMF\u00a0: C129H215N33O55
\nMW\u00a0: 3108.32
\nEINECS\u00a0: 1592732-453-0
\nCat\u00e9gories de produits\u00a0: Acides amin\u00e9s D\u00e9riv\u00e9s;Peptide;Peptides divers
\nMol File: 62304-98-7.mol<\/p>\n

Thymosin-\u03b11 (T-\u03b11), un peptide synth\u00e9tique de 28 acides amin\u00e9s avec de multiples activit\u00e9s biologiques principalement dirig\u00e9es vers la r\u00e9ponse immunitaire am\u00e9lioration, ce m\u00e9dicament est utilis\u00e9 pour le traitement des infections par le VHB et le virus de l'h\u00e9patite C (VHC), et en cours de d\u00e9veloppement pour le traitement du cancer du poumon non \u00e0 petites cellules (NSCLC), du carcinome h\u00e9patocellulaire, du SIDA et du m\u00e9lanome malin. T-\u03b11 est capable de potentialiser l'action des cytokines et \u00e9galement de r\u00e9duire la toxicit\u00e9 h\u00e9matologique des traitements m\u00e9dicamenteux cytotoxiques, tels que le cyclophosphamide, le 5-fluorouracile, la dacarbazine.<\/p>\n

Thymosin \u03b11\/ Thymosin \u03b11 \/ AcetateThymosin Alpha 1 CAS 162304- 98-7 Propri\u00e9t\u00e9s chimiques<\/strong>
\nPoint d'\u00e9bullition 2899,7\u00b165,0 \u00b0C(Pr\u00e9vu)
\ndensit\u00e9 1,360\u00b10,06 g\/cm3(Pr\u00e9vu)
\ntemp. de stockage. \u221220\u00b0C
\nsolubilit\u00e9 Il est recommand\u00e9 de reconstituer la Thymosine a1 lyophilis\u00e9e dans 18M\u03a9-cm H2O st\u00e9rile pas moins de 100 \u03bcg\/ml, qui peut ensuite \u00eatre dilu\u00e9e dans d'autres solutions aqueuses.
\ncouleur St\u00e9rile Filtr\u00e9 Blanc lyophilis\u00e9 poudre (lyophilis\u00e9e).
\nStabilit\u00e9\u00a0: La thymosine a1 lyophilis\u00e9e, bien que stable \u00e0 temp\u00e9rature ambiante pendant 3 semaines, doit \u00eatre conserv\u00e9e dess\u00e9ch\u00e9e \u00e0 une temp\u00e9rature inf\u00e9rieure \u00e0 -18\u00a0\u00b0C. Apr\u00e8s reconstitution, la thymalfasine doit \u00eatre conserv\u00e9e \u00e0 4 \u00b0C entre 2 et 7 jours et pour une utilisation future \u00e0 une temp\u00e9rature inf\u00e9rieure \u00e0 -18 \u00b0C.
\nPour une conservation \u00e0 long terme, il est recommand\u00e9 d'ajouter une prot\u00e9ine porteuse (0,1% de HSA ou BSA).<& >Veuillez \u00e9viter les cycles de gel-d\u00e9gel.<\/p>\n

Fonction et application de la thymosine \u03b11\/ Thymosine \u03b11 \/ Ac\u00e9tateThymosine Alpha 1 CAS 162304-98-7<\/strong>
\nLa thymosine \u03b11 est une thymosine \u03b11 synth\u00e9tis\u00e9e chimiquement qui est identique \u00e0 la thymosine humaine 1. La thymosine 1 est un polypeptide ac\u00e9tyl\u00e9. La thymosine \u03b11 est actuellement approuv\u00e9e pour le traitement des h\u00e9patites B et C dans 35 pays en d\u00e9veloppement. De plus, la thymosine \u03b11 est utilis\u00e9e pour am\u00e9liorer la r\u00e9ponse immunitaire dans le traitement d'autres maladies.<\/p>\n

Avantages de la thymosine alpha 1<\/strong>
\nLa thymalfasine (thymosine-alpha 1) est un agent immunomodulateur capable d'am\u00e9liorer la r\u00e9ponse immunitaire Thl. In vitro : la conjugaison de la thymalfasine (T\u03b11) avec l'iRGD pr\u00e9serve l'activit\u00e9 immunomodulatrice du m\u00e9dicament en augmentant la prolif\u00e9ration des lymphocytes de la rate de souris. En outre, par rapport au traitement T\u03b11, le traitement T\u03b11-iRGD des cellules MCF-7 augmente consid\u00e9rablement le nombre de cellules subissant l'apoptose, entra\u00eenant une inhibition dose-d\u00e9pendante de la croissance des cellules canc\u00e9reuses. <\/p>\n

In vivo\u00a0: la thymalfasine s'est av\u00e9r\u00e9e efficace dans plusieurs mod\u00e8les exp\u00e9rimentaux de dysfonctionnement immunitaire, principalement dans les maladies infectieuses telles que l'h\u00e9patite (marmotte) et la grippe (souris), et le cancer comme le m\u00e9lanome (souris) et colorectal carcinome (rat) o\u00f9 la thymalfasine a montr\u00e9 des effets antitumoraux. <\/p>\n

Dosage de la thymosine alpha 1<\/strong>
\n Cela d\u00e9pend de votre poids corporel. Toutes les recherches men\u00e9es jusqu'\u00e0 pr\u00e9sent ont utilis\u00e9 des \u00e9tudes sur des rongeurs, les rats et les souris re\u00e7oivent g\u00e9n\u00e9ralement une injection d'une dose efficace estim\u00e9e \u00e0 environ 10 g (mcg) par KG, chez l'homme, on pense qu'elle est d'environ la charge \u00e9quivalente de 1,6 g par KG chez l'homme, donc si vous \u00eates\u00a0: > 112 g
\n80 KG (176 lb.) => 128 g
\n90 KG (198 lb.) => 144 g<\/p>\n","protected":false},"excerpt":{"rendered":"

Nom du produit : Thymosine \u03b11
\nCAS : 62304-98-7
\nMF : C129H215N33O55
\nMW : 3108.32
\nEINECS : 1592732-453-0
\nMol Fichier : 62304-98-7.mol<\/p>\n","protected":false},"featured_media":2101,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[366],"product_tag":[1459],"class_list":{"0":"post-8191","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptide-immunomodulateur","7":"product_tag-thymosin-1-thymosin-1-acetatethymosin-alpha-1-cas-162304-98-7-for-treat-chronic-hepatitis-b-and-boosting-the-immune-system-fr","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product\/8191","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/comments?post=8191"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media\/2101"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media?parent=8191"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_brand?post=8191"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_cat?post=8191"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_tag?post=8191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}