{"id":8628,"date":"2021-12-17T01:50:40","date_gmt":"2021-12-17T06:50:40","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/utilisation-de-lacetate-dicatibant-cas-30308-48-4-pour-traiter-loedeme-de-quincke-hereditaire\/"},"modified":"2021-12-17T01:50:40","modified_gmt":"2021-12-17T06:50:40","slug":"utilisation-de-lacetate-dicatibant-cas-30308-48-4-pour-traiter-loedeme-de-quincke-hereditaire","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fr\/product\/utilisation-de-lacetate-dicatibant-cas-30308-48-4-pour-traiter-loedeme-de-quincke-hereditaire\/","title":{"rendered":"Utilisation de l'ac\u00e9tate d'Icatibant CAS 30308-48-4 pour traiter l'\u0153d\u00e8me de Quincke h\u00e9r\u00e9ditaire"},"content":{"rendered":"

Utilisation de l'ac\u00e9tate d'Icatibant CAS 30308-48-4 pour traiter l'\u0153d\u00e8me de Quincke h\u00e9r\u00e9ditaire<\/strong><\/h2>\n

Nom du produit\u00a0: Icatibant Acetate
\nSynonymes\u00a0: Icatibant Acetate;Icatibant Impurity;Itibantide Acetate
\nCAS\u00a0: 130308-48-4
\nS\u00e9quence\u00a0: HD-Arg-Arg-Pro-Hyp-Gly-Thi- Ser-D-Tic-Oic-Arg-OH
\nFormule mol\u00e9culaire : C59H89N19O13S
\nPoids mol\u00e9culaire : 1304.54<\/p>\n

Eltebante, un antagoniste comp\u00e9titif s\u00e9lectif du r\u00e9cepteur de la bradykinine de type 2 (B2), est un d\u00e9capeptide avec une structure de type bradykinine avec cinq acides amin\u00e9s non d\u00e9riv\u00e9s de prot\u00e9ines. La commercialisation d'Eltebante a \u00e9t\u00e9 approuv\u00e9e dans l'UE d\u00e8s le 1er novembre 2010 pour le traitement des crises aigu\u00ebs d'angio-\u0153d\u00e8me h\u00e9r\u00e9ditaire (AOH).<\/p>\n

Fonction et application de l'ac\u00e9tate d'icatibant CAS 30308-48-4<\/strong>
\nEltebante L'ac\u00e9tate est un antagoniste comp\u00e9titif puissant et s\u00e9lectif des r\u00e9cepteurs de la bradykinine de type 2 (B2) qui traite le gonflement local des emboles dans l'AOH aigu en inhibant les effets de la bradykinine associ\u00e9s au gonflement local embolique, \u00e0 l'inflammation et aux sympt\u00f4mes douloureux de l'AOH. L'AOH n'est que la premi\u00e8re de plusieurs indications pouvant \u00eatre trait\u00e9es avec l'ac\u00e9tate d'eltebante ; d'autres indications potentielles sont l'asthme, la cirrhose et d'autres types d'\u0153d\u00e8me de Quincke.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nom du produit : Icatibant Acetate
\nCAS : 130308-48-4
\nS\u00e9quence : HD-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
\nFormule mol\u00e9culaire : C59H89N19O13S
\nPoids mol\u00e9culaire : 1304.54<\/p>\n","protected":false},"featured_media":2122,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[408],"product_tag":[1122],"class_list":{"0":"post-8628","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-sang-et-peptide-vasculaire","7":"product_tag-icatibant-acetate-cas-30308-48-4-use-for-treat-hereditary-angioedema-fr","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product\/8628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/comments?post=8628"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media\/2122"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media?parent=8628"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_brand?post=8628"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_cat?post=8628"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_tag?post=8628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}