{"id":8792,"date":"2021-12-17T03:06:11","date_gmt":"2021-12-17T08:06:11","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/acetate-cas-214766-78-6-dapprovisionnement-de-puya-degarelix-utilise-pour-traiter-le-cancer-de-la-prostate\/"},"modified":"2021-12-17T03:06:11","modified_gmt":"2021-12-17T08:06:11","slug":"acetate-cas-214766-78-6-dapprovisionnement-de-puya-degarelix-utilise-pour-traiter-le-cancer-de-la-prostate","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fr\/product\/acetate-cas-214766-78-6-dapprovisionnement-de-puya-degarelix-utilise-pour-traiter-le-cancer-de-la-prostate\/","title":{"rendered":"Ac\u00e9tate CAS 214766-78-6 d'approvisionnement de Puya Degarelix utilis\u00e9 pour traiter le cancer de la prostate"},"content":{"rendered":"

Ac\u00e9tate CAS 214766-78-6 d'approvisionnement de Puya Degarelix utilis\u00e9 pour traiter le cancer de la prostate<\/strong><\/h2>\n

Nom du produit\u00a0: DEGARELIX
\nSynonymes\u00a0: DEGARELIX;Degarelix ac\u00e9tate\u00a0;N-Acetyl-3-(2-naphtyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D -alanyl-L-s\u00e9ryl-4-[2,6-dioxohexahydropyrimidine-4(S)-ylcarboxamido]-L-ph\u00e9nylalanyl-4-ur\u00e9ido-D-ph\u00e9nylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L- ac\u00e9tate de prolyl-D-alaninamide\u00a0;sel d'ac\u00e9tate de d\u00e9gar\u00e9lix\u00a0;D-alaninamide, N-ac\u00e9tyl-3-(naphtal\u00e9n-2-yl)-D-alanyl-4-chloro-D-ph\u00e9nylalanyl-3-(pyridin-3-yl) -D-alanyl-L-s\u00e9ryl-4-((((4S)-2,6-dioxohexahydropyrimidine-4-yl)carbonyl)amino)-L-ph\u00e9nylalanyl-4-(carbamoylamino)-D-ph\u00e9nylalanyl-L-leucyle -N6-(1-m\u00e9thyl\u00e9thyl)-L-lysyl-L-prolyl-; Ac\u00e9tate de Degarelix(FE-200486,Degarelix);FirMagon;Degarelix, Ac\u00e9tate de Degarelix
\nCAS: 214766-78-6
\nMF: C82H103ClN18O16
\nMW\u00a0: 1632.26
\nEINECS\u00a0: 807-277-4
\nCat\u00e9gories de produits\u00a0: API
\nFichier Mol\u00a0: 214766-78-6.mol<\/p>\n

Les antagonistes de la GnRH se sont av\u00e9r\u00e9s \u00eatre un th\u00e9rapie efficace pour les cancers r\u00e9gul\u00e9s hormonalement, tels que la prostate et certains types de sein. En tant qu'analogues de la GnRH, ils se lient de mani\u00e8re comp\u00e9titive et r\u00e9versible aux r\u00e9cepteurs de la GnRH dans l'hypophyse, bloquant ainsi la lib\u00e9ration de l'hormone lut\u00e9inisante (LH) et de l'hormone folliculo-stimulante (FSH). Chez les hommes, la r\u00e9duction de la LH d\u00e9clenche l'ablation de la s\u00e9cr\u00e9tion de testost\u00e9rone par les testicules, et ces niveaux de type castration ont \u00e9t\u00e9 essentiels dans la gestion efficace du cancer de la prostate avanc\u00e9. Par rapport aux agonistes de la GnRH, les antagonistes ne souffrent pas d'une pouss\u00e9e potentielle de la maladie \u00e0 la suite d'une stimulation initiale de l'axe hypothalamo-hypophyso-gonadique avant la r\u00e9gulation n\u00e9gative du r\u00e9cepteur de la GnRH. De plus, les antagonistes de la GnRH produisent des effets b\u00e9n\u00e9fiques plus rapidement apr\u00e8s l'administration et entra\u00eenent une suppression plus efficace des niveaux de gonadotrophine. Dans cet esprit, l'ac\u00e9tate de d\u00e9gar\u00e9lix a \u00e9t\u00e9 lanc\u00e9 en tant qu'antagoniste de la GnRH de troisi\u00e8me g\u00e9n\u00e9ration pour le traitement du cancer de la prostate, et il rejoint d'autres agents de troisi\u00e8me g\u00e9n\u00e9ration, le ganirelix et le c\u00e9tronelix, sur le march\u00e9.<\/p>\n

Propri\u00e9t\u00e9s chimiques de Degarelix Acetate CAS 214766-78-6<\/strong>
\n densit\u00e9 1,325 \u00b1 0,06 g\/cm3 (pr\u00e9vu)
\n temp\u00e9rature de stockage. Conserver dans un endroit sombre, atmosph\u00e8re inerte, conserver au cong\u00e9lateur, \u00e0 moins de -20 \u00b0C
\npka 10,38 \u00b1 0,40 (pr\u00e9vu)<\/p>\n

Fonction et application de l'ac\u00e9tate de Degarelix CAS 214766-78-6<\/strong>
\nHormone avanc\u00e9e Le carcinome de la prostate d\u00e9pendant<\/p>\n

Desmopressin' (noms commerciaux : DDAVP, DesmoMelt, Minirin, Minirin Melt, Octim, Stimate) est un substitut synth\u00e9tique de la vasopressine, l'hormone qui r\u00e9duit la production d'urine. Il peut \u00eatre pris par voie nasale, intraveineuse ou sous forme de comprim\u00e9 oral ou sublingual. Les m\u00e9decins prescrivent la desmopressine le plus souvent pour le traitement du diab\u00e8te insipide, de l'\u00e9nur\u00e9sie nocturne ou de la nycturie.<\/p>\n

Il peut \u00eatre pris par voie nasale, intraveineuse ou sous forme de comprim\u00e9. Les m\u00e9decins prescrivent Desmopressin' le plus souvent pour le traitement du diab\u00e8te insipide ou de l'\u00e9nur\u00e9sie nocturne. La desmopressine (1-desamino-8-D-arginine vasopressine) est une forme modifi\u00e9e de l'hormone humaine normale arginine vasopressine, un peptide contenant neuf acides amin\u00e9s. L'utilisation m\u00e9dicale de l'ac\u00e9tate de desmopressine comprend : (a) l'\u00e9nur\u00e9sie nocturne; (b) miction nocturne; (c) troubles de la coagulation; (d) diab\u00e8te insipide.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nom du produit : DEGARELIX
\nCAS : 214766-78-6
\nMF : C82H103ClN18O16
\nMW : 1632.26
\nEINECS : 807-277-4
\nCat\u00e9gories de produits : API
\nMol File : 214766 -78-6.mol<\/p>\n","protected":false},"featured_media":2122,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[395],"product_tag":[935],"class_list":{"0":"post-8792","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptide-anti-tumoral","7":"product_tag-puya-supply-degarelix-acetate-cas-214766-78-6-used-for-treat-prostate-cancer-fr","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product\/8792","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/comments?post=8792"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media\/2122"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media?parent=8792"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_brand?post=8792"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_cat?post=8792"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_tag?post=8792"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}