{"id":8850,"date":"2021-12-17T03:09:54","date_gmt":"2021-12-17T08:09:54","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-cetrorelix-acetate-cas-120287-85-6-antagoniste-du-recepteur-de-linhibiteur-de-lhormone-de-liberation-de-lhormone-luteinisante-lh-rh\/"},"modified":"2021-12-17T03:09:54","modified_gmt":"2021-12-17T08:09:54","slug":"puya-supply-cetrorelix-acetate-cas-120287-85-6-antagoniste-du-recepteur-de-linhibiteur-de-lhormone-de-liberation-de-lhormone-luteinisante-lh-rh","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/fr\/product\/puya-supply-cetrorelix-acetate-cas-120287-85-6-antagoniste-du-recepteur-de-linhibiteur-de-lhormone-de-liberation-de-lhormone-luteinisante-lh-rh\/","title":{"rendered":"Puya Supply Cetrorelix Acetate CAS 120287-85-6 Antagoniste du r\u00e9cepteur de l'inhibiteur de l'hormone de lib\u00e9ration de l'hormone lut\u00e9inisante (LH-RH)"},"content":{"rendered":"

Puya Supply Cetrorelix Acetate CAS 120287-85-6 Antagoniste du r\u00e9cepteur de l'inhibiteur de l'hormone de lib\u00e9ration de l'hormone lut\u00e9inisante (LH-RH)<\/strong><\/h2>\n

Nom du produit\u00a0: ac\u00e9tate de c\u00e9trorelix
\nSynonymes\u00a0: AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3 -PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH;Cetrorelix ac\u00e9tate;CETRORELIX;CETRORELIX ACID;CETRIZINEDIHYDROCHLORIDE;N-Acetyl-3-(2-naphthalenyl)- D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg- L-Pro-D-Ala-NH2;Cetrorelixum;Cetrorelixum [auberge-latin]
\nCAS\u00a0: 120287-85-6
\nMF\u00a0: C70H92ClN17O14
\nMW\u00a0: 1431.04
\nEINECS\u00a0: 686-384-6
\nCat\u00e9gories de produits\u00a0: Peptide
\nMol File\u00a0: 120287-85-6.mol<\/p>\n

Cetrorelix a \u00e9t\u00e9 lanc\u00e9 en Allemagne pour le traitement de l'infertilit\u00e9 f\u00e9minine. C'est un analogue d\u00e9capeptidique de l'hormone de lib\u00e9ration de l'hormone lut\u00e9inisante (LH-RH) portant des modifications structurelles dans les positions cruciales 1, 2, 3, 6 et 10 : [Ac-D-Nal1, D-4-CI Phe-2, D -Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix est un antagoniste de l'hormone de lib\u00e9ration des gonadotrophines (GnRH) extr\u00eamement puissant et \u00e0 action prolong\u00e9e et bloque ainsi la s\u00e9cr\u00e9tion des gonadotrophines et des st\u00e9ro\u00efdes sexuels imm\u00e9diatement apr\u00e8s l'administration. De plus, il a une faible puissance de lib\u00e9ration d'histamine. Cetrorelix sera le premier antagoniste de la LH-RH approuv\u00e9 dans le monde. Dans plusieurs essais cliniques de phase III, les patientes recevant Cetrorelix ont eu une ovulation contr\u00f4l\u00e9e avec succ\u00e8s, \u00e9vitant ainsi une augmentation pr\u00e9matur\u00e9e de la LH. Cetrorelix pourrait \u00eatre un traitement de premier choix pour la f\u00e9condation in vitro (FIV) sans les complications des protocoles actuels d'hyperstimulation ovarienne contr\u00f4l\u00e9e. Cetrorelix fait actuellement l'objet d'\u00e9tudes cliniques pour le traitement de divers troubles d\u00e9pendants des hormones sexuelles tels que l'hypertrophie b\u00e9nigne de la prostate, les cancers du sein, de l'ovaire ou de la prostate et divers troubles gyn\u00e9cologiques.<\/p>\n

Cetrorelix Acetate Propri\u00e9t\u00e9s chimiques de Cetrorelix Acetate CAS 120287-85- 6<\/strong>
\ndensit\u00e9 1,42\u00b10,1 g\/cm3 (pr\u00e9dit)
\npka 9,82\u00b10,15 (pr\u00e9dit)<\/p>\n

Fonction et application de l'ac\u00e9tate de Cetrorelix CAS 120287-85-6<\/strong>
\nL'ac\u00e9tate de Cetrorelix, aussi souvent appel\u00e9 cetrorelix, est un puissant antagoniste des r\u00e9cepteurs inhibiteur de l'hormone de lib\u00e9ration de l'hormone lut\u00e9inisante (LChemicalbookH-RH) qui contr\u00f4le la stimulation ovarienne, emp\u00eache l'expulsion pr\u00e9matur\u00e9e des follicules immatures et facilite la conception, et est donc souvent utilis\u00e9 comme pr\u00e9paration injectable de cetrorelix.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nom du produit\u00a0: ac\u00e9tate de Cetrorelix
\nCAS\u00a0: 120287-85-6
\nMF\u00a0: C70H92ClN17O14
\nMW\u00a0: 1431.04
\nEINECS\u00a0: 686-384-6
\nCat\u00e9gories de produits\u00a0: Peptide
\nMol File\u00a0: 120287-85-6.mol<\/p>\n","protected":false},"featured_media":2332,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[428],"product_tag":[904],"class_list":{"0":"post-8850","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptide-urogenital","7":"product_tag-puya-supply-cetrorelix-acetate-cas-120287-85-6-fr","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product\/8850","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/comments?post=8850"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media\/2332"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/media?parent=8850"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_brand?post=8850"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_cat?post=8850"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/fr\/wp-json\/wp\/v2\/product_tag?post=8850"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}