{"id":8771,"date":"2021-12-17T03:04:36","date_gmt":"2021-12-17T08:04:36","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/kualitas-tinggi-goserelin-acetate-cas-145781-92-6-digunakan-untuk-mengobati-kanker-payudara\/"},"modified":"2021-12-17T03:04:36","modified_gmt":"2021-12-17T08:04:36","slug":"kualitas-tinggi-goserelin-acetate-cas-145781-92-6-digunakan-untuk-mengobati-kanker-payudara","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/id\/product\/kualitas-tinggi-goserelin-acetate-cas-145781-92-6-digunakan-untuk-mengobati-kanker-payudara\/","title":{"rendered":"Kualitas Tinggi Goserelin Acetate CAS 145781-92-6 Digunakan Untuk Mengobati Kanker Payudara"},"content":{"rendered":"

Kualitas Tinggi Goserelin Acetate CAS 145781-92-6 Digunakan Untuk Mengobati Kanker Payudara<\/strong><\/h2>\n

Nama Produk: Goserelin acetate
\nSinonim: PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;[(T-BU)DSER6, (AZA )GLY10]-LH-RH;[(T-BU)DSER6, (AZA)GLY10]-LUTEINIZING HORMONE-RELEASING HORMONE;ICI-118630 acetate;GOSERELIN HCL[PYR-HIS-TRP-SER-TYR-D-SER( T-BU)-LEU-ARG-PRO-AZAGLY-NH2];1-9-Luteinizing hormone-releasing factor (babi), 6-(o-(1,1-dimethylethyl)-D-serine)-, 2- (aminokarbonil)hidrazida, asetat (garam);Fertilan;GLP-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZA-GLY-NH2
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nKategori Produk: Peptida;Pepetida;Turunan Asam Amino;Bahan Kimia Menengah & Halus;Peptida;Farmasi
\nBerkas Mol: 145781-92-6.mol<\/p>\n

Goserelin acetate, seperti leuprolide acetate, adalah analog superagonis nonapeptide GnRH sintetik yang memiliki potensi lebih besar daripada hormon alami. Perhatikan bahwa ini mengandung D-Ser(Tapi) dan NH-NHCONH2 masing-masing menggantikan Gly6 dan Gly10-NH2. Artinya, modifikasi terminal C hanya memiliki NH yang menggantikan CH2 dari Gly, dan seperti perubahan terminal-C pada leuprolide asetat, ini menghambat degradasi enzimatik peptida oleh postproline carboxyamide peptidase.
\nGoserelin asetat tersedia dalam bentuk pelet padat kecil yang diberikan sebagai implan SC untuk pengobatan paliatif kanker payudara metastatik stadium lanjut pada wanita pra dan perimenopause atau, dengan cara yang sama, sebagai paliatif pada kanker prostat stadium lanjut. Alasan penggunaan obat ini adalah, seperti dijelaskan di atas, kemampuannya sebagai superagonis untuk membawa tingkat estradiol atau testosteron mendekati tingkat kastrasi, sehingga memperlambat perkembangan karsinoma payudara atau prostat, masing-masing. Selain itu, goserelin acetate disetujui untuk digunakan dalam pengobatan endometriosis hingga 6 bulan.<\/p>\n

Goserelin acetate CAS 145781-92-6 Sifat Kimia<\/strong>
\nTitik leleh >190\u00b0C (des.)
\npenyimpanan suhu -20\u00b0C
\nkelarutan H2O: 20 mg\/mL, bening, tidak berwarna
\nbentuk bubuk putih
\nInChIKey IKDXDQDKCZPQSZ-JHYYTBFNSA-N
\nReferensi Basis Data CAS 145781-92-6<\/p>\n

Fungsi dan Aplikasi Goserelin acetate CAS 145781-92-6<\/strong>
\n1. Antikanker
\n2. superagonis hormon pelepas gonadotropin suntik (GnRH agonis) atau aktivitas antiproliferatif hormon luteinizing pada kanker payudara, prostat dan endometrium
\n3. Analog agonis peptida sintetik dari LH-RH. Antineoplastik (hormonal).<\/p>\n","protected":false},"excerpt":{"rendered":"

Nama Produk: Goserelin acetate
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nMol File: 145781-92-6.mol<\/p>\n","protected":false},"featured_media":2209,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[382],"product_tag":[957],"class_list":{"0":"post-8771","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptida-anti-tumor","7":"product_tag-goserelin-acetate-cas-145781-92-6-used-for-treat-breast-cancer-id","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/product\/8771","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/comments?post=8771"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/media\/2209"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/media?parent=8771"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/product_brand?post=8771"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/product_cat?post=8771"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/id\/wp-json\/wp\/v2\/product_tag?post=8771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}