{"id":7737,"date":"2021-12-16T10:30:02","date_gmt":"2021-12-16T15:30:02","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-cilengitide-cas-188968-51-6-per-la-ricerca-di-laboratorio\/"},"modified":"2021-12-16T10:30:02","modified_gmt":"2021-12-16T15:30:02","slug":"puya-supply-cilengitide-cas-188968-51-6-per-la-ricerca-di-laboratorio","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/it\/product\/puya-supply-cilengitide-cas-188968-51-6-per-la-ricerca-di-laboratorio\/","title":{"rendered":"Puya Supply Cilengitide CAS 188968-51-6 per la ricerca di laboratorio"},"content":{"rendered":"<h2><strong>Puya Supply Cilengitide CAS 188968-51-6 per la ricerca di laboratorio<\/strong><\/h2>\n<p>Nome prodotto: cilengitide<br \/>\nSequenza: cyclo(Arg-Gly-Asp-D-Phe-N-Me-Val)<br \/>\nSinonimi: 2-[(2S,5R,8S,11S)-5- benzil-11-[3-(diaminometilideneamino)propil]-7-metil-3,6,9,12,15-pentaosso-8-propan-2-il-1,4,7,10,13-pentazaciclopentadec-2 acido -il]acetico;Ciclo(L-arginilglicil-L-aspartil-D-fenilalanil-N-metil-L-valile);Cilengitide(EMD121974,NSC-707544);Cilengitide;C(RGDf-Me-V);EMD 121974;EMD-121974;EMD121974;CS-1500;CS-2674<br \/>\nCAS: 188968-51-6<br \/>\nMF: C27H40N8O7<br \/>\nMW: 588,66<br \/>\nEINECS:<br \/>\nCategorie di prodotto: Inibitori&lt; &amp;&gt;Mol File: 188968-51-6.mol<\/p>\n<p>Cilengitide \u00e8 un peptide ciclico contenente la sequenza RGD. Il peptide si basa sul ligando dell&#39;integrina \u03b1v \u03b23 in vivo ed \u00e8 stato ottenuto mediante una combinazione di ciclizzazione, screening spaziale e scansione di metilazione, con elevata affinit\u00e0 e selettivit\u00e0 per le integrine \u03b1v \u03b23. I test hanno dimostrato che il peptide non solo pu\u00f2 inibire meglio la crescita del melanoma e del glioblastoma, ma pu\u00f2 anche migliorare il tasso di guarigione di altri tumori come i tumori a cellule squamose della testa e del collo in combinazione con la radioterapia, che ha buone prospettive di mercato e potenziale . Nella sintesi peptidica, la cilengitide \u00e8 stata prodotta combinando la tecnologia di sintesi peptidica in fase solida con la tecnologia di sintesi peptidica in fase liquida.<\/p>\n<p> <strong>cilengitide CAS 188968-51-6 Propriet\u00e0 chimiche<\/strong><br \/>\ndensit\u00e0 1,41\u00b10,1 g\/cm3 (prevista)&lt; &amp;&gt;temp. -20\u00b0C<br \/>\nforma polvere<br \/>\npka 4.01\u00b10.10(Predicted)<br \/>\ncolore da bianco a beige<\/p>\n<p> <strong>Usi di cilengitide CAS 188968-51-6<\/strong><br \/>\nInibitore dell&#39;angiogenesi.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nome del prodotto: cilengitide<br \/>\nCAS: 188968-51-6<br \/>\nMF: C27H40N8O7<br \/>\nMW: 588,66<br \/>\nMol File: 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