{"id":8781,"date":"2021-12-17T03:06:07","date_gmt":"2021-12-17T08:06:07","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/goserelin-acetate-cas-145781-92-6-berkualiti-tinggi-digunakan-untuk-merawat-kanser-payudara\/"},"modified":"2021-12-17T03:06:07","modified_gmt":"2021-12-17T08:06:07","slug":"goserelin-acetate-cas-145781-92-6-berkualiti-tinggi-digunakan-untuk-merawat-kanser-payudara","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/ms\/product\/goserelin-acetate-cas-145781-92-6-berkualiti-tinggi-digunakan-untuk-merawat-kanser-payudara\/","title":{"rendered":"Goserelin Acetate CAS 145781-92-6 Berkualiti Tinggi Digunakan Untuk Merawat Kanser Payudara"},"content":{"rendered":"

Goserelin Acetate CAS 145781-92-6 Berkualiti Tinggi Digunakan Untuk Merawat Kanser Payudara<\/strong><\/h2>\n

Nama Produk: Goserelin acetate
\nSinonim: PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;[(T-BU)DSER6, (AZA )GLY10]-LH-RH;[(T-BU)DSER6, (AZA)GLY10]-HORMON PELEPAS HORMON PENLUTEIN;ICI-118630 asetat;GOSERELIN HCL[PYR-HIS-TRP-SER-TYR-D-SER( T-BU)-LEU-ARG-PRO-AZAGLY-NH2];1-9-Faktor pelepas hormon lutein (babi), 6-(o-(1,1-dimethylethyl)-D-serine)-, 2- (aminocarbonyl)hydrazide, asetat (garam);Fertilan;GLP-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZA-GLY-NH2
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nKategori Produk: Peptida;Pepetida;Derivatif Asid Amino;Perantaraan & Bahan Kimia Halus;Peptida;Fail Farmaseutikal:
\n 145781-92-6.mol<\/p>\n

Goserelin acetate, seperti leuprolide acetate, ialah analog nonapeptida superagonist sintetik bagi GnRH yang mempunyai potensi lebih besar daripada hormon semula jadi. Ambil perhatian bahawa ia mengandungi D-Ser(Tetapi) dan NH-NHCONH2 sebagai ganti Gly6 dan Gly10-NH2, masing-masing. Iaitu, pengubahsuaian terminal C hanya mempunyai pengganti NH untuk CH2 Gly, dan seperti perubahan terminal C dalam leuprolide asetat, ini menghalang degradasi enzimatik peptida oleh peptidase karboksiamida postproline.
\nGoserelin acetate tersedia dalam bentuk pelet kecil dan pepejal yang ditadbir sebagai implan SC untuk rawatan paliatif kanser payudara metastatik lanjutan pada wanita pra dan perimenopaus atau, begitu juga, sebagai paliatif dalam kanser prostat lanjutan. Rasional untuk penggunaan ubat ini adalah, seperti yang diterangkan di atas, keupayaannya sebagai superagonist untuk membawa paras estradiol atau testosteron kepada paras kastrat hampir, sekali gus memperlahankan perkembangan karsinoma payudara atau prostat, masing-masing. Selain itu, goserelin acetate diluluskan untuk digunakan dalam merawat endometriosis sehingga 6 bulan.<\/p>\n

Goserelin acetate CAS 145781-92-6 Sifat Kimia<\/strong>
\nTakat lebur >190\u00b0C (dis.)
\nsimpanan temp. -20\u00b0C
\nketerlarutan H2O: 20 mg\/mL, jernih, tidak berwarna
\nmembentuk serbuk putih
\nInChIKey IKDXDQDKCZPQSZ-JHYYTBFNSA-N
\nRujukan Pangkalan Data CAS 145781-92-6<\/p>\n

Fungsi dan Aplikasi Goserelin acetate CAS 145781-92-6<\/strong>
\n1. Antikanser
\n2. superagonist hormon pelepas gonadotropin suntikan (agonis GnRH) atau aktiviti antiproliferatif hormon lutein dalam payudara, prostat dan kanser endometrium
\n3. Analog agonis peptida sintetik LH-RH. Antineoplastik (hormon).<\/p>\n","protected":false},"excerpt":{"rendered":"

Nama Produk: Goserelin acetate
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nMol File: 145781-92-6.mol<\/p>\n","protected":false},"featured_media":4552,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[383],"product_tag":[967],"class_list":{"0":"post-8781","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptida-anti-tumor","7":"product_tag-goserelin-acetate-cas-145781-92-6-used-for-treat-breast-cancer-ms","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/product\/8781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/comments?post=8781"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/media\/4552"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/media?parent=8781"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/product_brand?post=8781"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/product_cat?post=8781"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/ms\/wp-json\/wp\/v2\/product_tag?post=8781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}