{"id":7317,"date":"2021-12-16T07:21:48","date_gmt":"2021-12-16T12:21:48","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/carperitide-acetaat-anp-1-28-human-cas-89213-87-6-voor-de-behandeling-van-congestief-hartfalen\/"},"modified":"2021-12-16T07:21:48","modified_gmt":"2021-12-16T12:21:48","slug":"carperitide-acetaat-anp-1-28-human-cas-89213-87-6-voor-de-behandeling-van-congestief-hartfalen","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/nl\/product\/carperitide-acetaat-anp-1-28-human-cas-89213-87-6-voor-de-behandeling-van-congestief-hartfalen\/","title":{"rendered":"Carperitide-acetaat\/ANP 1-28, HUMAN CAS 89213-87-6 Voor de behandeling van congestief hartfalen"},"content":{"rendered":"

Carperitide-acetaat\/ANP 1-28, HUMAN CAS 89213-87-6 Voor de behandeling van congestief hartfalen<\/strong><\/h2>\n

Productnaam: Carperitide Acetate\/ANP 1-28, HUMAN
\nSequence: H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg- Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH\uff0c (Disulfidebrug: Cys-Cys)
\n Synoniemen: ATRIAL NATRIURETIC PEPTIDE HUMAN;SER- LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER- PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDE BRUG CYS7-CYS23.;Carperitide Acetate, carperitida;Atriale Natriuretic Peptide (1-28) (humaan) (trifluoracetaatzout);ahANF, Carperitide;H-Seritide;H-Seritide Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe- Arg-Tyr-OH;Atriale natriuretische peptide-28 (mens) (9CI);Atriale natriuretische factor (1-28) (mens) \u03b1hANF, Carperitide
\nCAS: 89213-87-6
\nMF: C127H203N45O39S3
\n MW: 3080.44
\nEINECS: 686-482-9
\nProductcategorie\u00ebn: peptide
\nMol File: 89213-87-6.mol<\/p>\n

Carperitide is een polypeptide van 28 aminozuren met een stabiele secundaire structuur en is een cir culatory hormoon dat werkt als een vasodilatator en diureticum. In de klinische praktijk is de vasodilatatie die wordt veroorzaakt door carperitide als hoofdbestanddeel te wijten aan binding aan ANP-receptoren (atriale natriuretisch polypeptide) in vasculaire gladde spieren, wat wordt bereikt door de activiteit van guanylaatcyclase te verhogen, wat wijst op een vermindering van de pre- en afterload van het hart. <\/p>\n

Carperitide is het \u03b1-humaan atriale natriuretisch peptide (\u03b1-hANP) geproduceerd door middel van recombinante technologie. Het werd in Japan ge\u00efntroduceerd als een behandeling voor acuut congestief hartfalen (CHF). Bij honden met CHF verminderde carperitide significant de verhoogde linkerventrikel einddiastolische druk en de index van myocardiaal zuurstofverbruik (systolische bloeddruk x hartslag). In een klinische studie was carperitide effectief bij het verbeteren van de hemodynamiek en symptomen bij 60% van de pati\u00ebnten met acuut CHF. Van carperitide werd gemeld dat het goed wordt verdragen zonder significante klinische bijwerkingen. Een gunstig effect op de hemodynamiek is gemeld bij pati\u00ebnten met chronisch hartfalen. Carperitide wordt ook gebruikt in klinische onderzoeken voor het handhaven van de bloeddruk tijdens chirurgische ingrepen.<\/p>\n

Toepassing<\/strong>
\nBehandeling van gedecompenseerd congestief hartfalen.<\/p>\n","protected":false},"excerpt":{"rendered":"

Productnaam: Carperitide Acetate\/ ANP 1-28, HUMAN
\nCAS: 89213-87-6
\nMF: C127H203N45O39S3
\nMW: 3080.44
\nEINECS: 686-482-9
\nMol-bestand: 89213-87-6.mol<\/p>\n","protected":false},"featured_media":2288,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[509],"product_tag":[2467,2489],"class_list":{"0":"post-7317","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardiovasculair-systeempeptide-carperitide-acetate-anp-1-28-human-cas-89213-87-6-nesiritide-bnp-32-human-cas-124584-08-3","7":"product_tag-carperitide-acetate-anp-1-28-nl","8":"product_tag-human-cas-89213-87-6-for-treatment-of-congestive-heart-failure-nl","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product\/7317","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/comments?post=7317"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media\/2288"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media?parent=7317"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_brand?post=7317"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_cat?post=7317"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_tag?post=7317"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}