{"id":7823,"date":"2021-12-16T11:16:33","date_gmt":"2021-12-16T16:16:33","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/dsip-sleep-inducing-peptide-cas-62568-57-4-hulp-om-goed-te-slapen\/"},"modified":"2021-12-16T11:16:33","modified_gmt":"2021-12-16T16:16:33","slug":"dsip-sleep-inducing-peptide-cas-62568-57-4-hulp-om-goed-te-slapen","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/nl\/product\/dsip-sleep-inducing-peptide-cas-62568-57-4-hulp-om-goed-te-slapen\/","title":{"rendered":"DSIP\/SLEEP-INDUCING PEPTIDE CAS 62568-57-4 Hulp om goed te slapen"},"content":{"rendered":"

Drotaverine Hidroklorida \/ Drotaverine Hcl CAS 985-12-6<\/strong><\/h2>\n

Productnaam: DSIP
\nSynoniemen: SLEEP INDUCING PEPTIDE;WAGGDASGE;TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER- GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O;DELTA SLEEP INDUCATIEVE PEPTIDE;DELTA SLAAP-INDUCERENDE PEPTIDE 4H2O;DSIP
\nCAS: 62568-57-4
\nMF : C35H48N10O15
\nMW: 848.82
\nEINECS: 211-519-9
\nProductcategorie\u00ebn: Peptide
\nMol File: 62568-57-4.mol<\/p>\n

Delta slaap-inducerend peptide, afgekort DSIP, is een neuropeptide dat bij infusie in de mesodiencephalische ventrikel van ontvangende konijnen spindel- en delta-EEG-activiteit en verminderde motorische activiteiten induceert.<\/p>\n

DSIP CAS 985-12-6 Chemische eigenschappen<\/strong>
\nKookpunt 1522,7 \u00b1 65,0 \u00b0C (voorspeld)
\ndichtheid 1,458\u00b10,06 g\/cm3 (voorspeld)
\nopslagtemp. \u221220 \u00b0C
\npka 3,18\u00b10,10(voorspeld)
\nOplosbaarheid in water Oplosbaar in water bij 0,5 mg\/ml
\nInChIKey ZRZROXNBKJAOKB-GFVHOAGBSA-N<\/p>\n

DSIP-functie<\/strong>
\nVele rollen voor DSIP is voorgesteld na onderzoek uitgevoerd met peptide-analogen met een grotere moleculaire stabiliteit en door het meten van DSIP-achtige immunologische (DSIP-LI) respons door DSIP-antiserum en antilichamen te injecteren<\/p>\n

Rollen in endocriene regulatie<\/strong>
\nVerlaagt basale corticotropinespiegel en blokkeert de afgifte ervan.
\nStimuleert de afgifte van lute\u00efniserend hormoon (LH).
\nStimuleert de afgifte van somatoliberine en somatotrofinesecretie en remt de somatostatinesecretie.<\/p>\n

Structuur en interacties<\/strong>
\nDSIP is een amfifiele peptide met een molecuulgewicht van 850 dalton met het aminozuurmotief: N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C
\nHet is gevonden in zowel vrije als gebonden vormen in de hypothalamus, limbisch systeem en hypofyse evenals verschillende perifere organen, weefsels en lichaamsvloeistoffen. In de hypofyse co-lokaliseert het met veel peptide- en niet-peptide-mediatoren zoals corticotropine-achtig intermediair peptide (CLIP), adrenocorticotroop hormoon (ACTH), melanocytstimulerend hormoon (MSH), schildklierstimulerend hormoon (TSH) en melanineconcentraat. hormoon (MCH). Het is overvloedig aanwezig in de darmsecretoire cellen en in de pancreas waar het co-lokaliseert met glucagon.
\nIn vitro is gevonden dat het een lage moleculaire stabiliteit heeft met een halfwaardetijd van slechts 15 minuten als gevolg van de werking van een specifiek aminopeptidase-achtig enzym. Er is gesuggereerd dat het in het lichaam een complex vormt met dragereiwitten om afbraak te voorkomen, of bestaat als een component van een groot voorlopermolecuul, maar tot nu toe is er geen structuur of gen gevonden voor deze voorloper.<\/p>\n","protected":false},"excerpt":{"rendered":"

Productnaam: DSIP
\nCAS: 62568-57-4
\nMF: C35H48N10O15
\nMW: 848.82
\nEINECS: 211-519-9
\nMol-bestand: 62568-57-4.mol<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[513],"product_tag":[1945],"class_list":{"0":"post-7823","1":"product","2":"type-product","3":"status-publish","5":"product_cat-andere-peptiden","6":"product_tag-dsip-sleep-inducing-peptide-cas-62568-57-4-help-for-sleep-well-nl","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product\/7823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/comments?post=7823"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media?parent=7823"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_brand?post=7823"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_cat?post=7823"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_tag?post=7823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}