{"id":8158,"date":"2021-12-16T12:21:07","date_gmt":"2021-12-16T17:21:07","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/triptorelin-triptorelin-acetaat-cas-57773-63-4-voor-de-behandeling-van-prostaatkanker-en-borstkanker\/"},"modified":"2021-12-16T12:21:07","modified_gmt":"2021-12-16T17:21:07","slug":"triptorelin-triptorelin-acetaat-cas-57773-63-4-voor-de-behandeling-van-prostaatkanker-en-borstkanker","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/nl\/product\/triptorelin-triptorelin-acetaat-cas-57773-63-4-voor-de-behandeling-van-prostaatkanker-en-borstkanker\/","title":{"rendered":"Triptorelin\/Triptorelin-acetaat CAS 57773-63-4 voor de behandeling van prostaatkanker en borstkanker;"},"content":{"rendered":"<h2><strong>Triptorelin\/Triptorelin-acetaat CAS 57773-63-4 voor de behandeling van prostaatkanker en borstkanker;<\/strong><\/h2>\n<p>Productnaam: Triptoreline<br \/>\nSynoniemen: PGLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2;PYROGLU-HIS-TRP-SER-TYR-D-TRP- LEU-ARG-PRO-GLY NH2;PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2;PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG -PRO-GLY-NH2 PAMOATE SALT;TRIPTORELIN PAMOATE;TRIPTORELINE ACETATE;TRIPTORELIN AMIDE;TRIPTORELIN, [DTRP6]-LH-RH, AMIDE<br \/>\nCAS: 57773-63-4<br \/>\nMF: C64H82N18O13<br \/>\nMW: 1311.47<br \/>\nEINECS: 637-328-4<br \/>\nProductcategorie\u00ebn: Aminozuurderivaten; Peptide<br \/>\nMol File: 57773-63-4.mol<\/p>\n<p>Triptoreli is een synthetisch decapeptide-agonist analoog vrijgevend hormoon (LHRH). Triptoreli heeft een grotere potentie dan endogeen LHRH en onderdrukt de secretie van gonadotropines omkeerbaar. Na chronische, continue toediening heeft dit middel een aanhoudende afname van de LH- en FSH-productie en testiculaire en ovari\u00eble stero\u00efdogenese. Serumconcentraties kunnen dalen tot niveaus die gewoonlijk worden waargenomen bij chirurgisch gecastreerde mannen.<\/p>\n<p> <strong>Triptoreline\/ Triptoreline-acetaat CAS 57773-63-4 Chemische eigenschappen<\/strong><br \/>\nalfa D23 -58,8\u00b0 (c = 0,33 in azijnzuur)<br \/>\n dichtheid 1,52\u00b10,1 g\/cm3 (voorspeld)<br \/>\nopslagtemp. -20\u00b0C<br \/>\npka 9,82\u00b10,15(voorspeld)<br \/>\nvorm poeder<br \/>\nInChIKey HPPONSCISKROOD-OYLNGHKZSA-N<br \/>\nCAS-databasereferentie 57773-63-4(CAS-databasereferentie)<\/p>\n<p> <strong>Functie en toepassing van triptoreline\/triptoreline-acetaat CAS 57773-63-4<\/strong><br \/>\nTriptoreli kan worden gebruikt bij de behandeling van hormoongevoelige kankers zoals prostaatkanker of borstkanker, vroegtijdige puberteit, oestrogeenafhankelijke aandoeningen (zoals endometriose of baarmoederkanker). vleesbomen), en bij geassisteerde voortplanting. Het wordt ook gebruikt als therapie voor genderidentiteitsstoornissen.<\/p>\n<p>Triptoreline-pamoaat is een andere superagonist van GnRH, dat net als nafareline-acetaat slechts een enkele aminozuursubstitutie bevat (D-Trp6 voor Gly6) in vergelijking met het natuurlijke hormoon. Bij de behandeling van gevorderde prostaatkanker is het belangrijk om de serumtestosteronspiegels tot zeer lage niveaus te verlagen, wat operatief kan worden bereikt door orchiectomie. Wanneer deze chirurgische methode onaanvaardbaar is voor de pati\u00ebnt, is een alternatieve benadering &quot;chemische castratie&quot;, die kan worden bereikt door het gebruik van oestrogeentherapie, leuprolide, gosereline of histreline-acetaat, en nu triptoreline-pamoaat. Dit product is beschikbaar voor IM-depotinjectie (maandelijks of elke 3 maanden), waarbij de serumtestosteronconcentratie daalt tot een niveau dat algemeen wordt gezien bij chirurgisch gecastreerde mannen.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Productnaam: Triptorelin<br \/>\nCAS: 57773-63-4<br \/>\nMF: C64H82N18O13<br \/>\nMW: 1311.47<br \/>\nEINECS: 637-328-4<br \/>\nMol-bestand: 57773-63-4.mol<\/p>\n","protected":false},"featured_media":2288,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[399],"product_tag":[1513],"class_list":{"0":"post-8158","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-antitumorpeptide","7":"product_tag-triptorelin-triptorelin-acetate-cas-57773-63-4-for-treat-prostate-cancer-and-breast-cancer-nl","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product\/8158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/comments?post=8158"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media\/2288"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media?parent=8158"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_brand?post=8158"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_cat?post=8158"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_tag?post=8158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}