{"id":8703,"date":"2021-12-17T03:00:38","date_gmt":"2021-12-17T08:00:38","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/ganirelix-acetaat-cas-123246-29-7-gonadotropine-releasing-hormoon-gnrh-antagonisten\/"},"modified":"2021-12-17T03:00:38","modified_gmt":"2021-12-17T08:00:38","slug":"ganirelix-acetaat-cas-123246-29-7-gonadotropine-releasing-hormoon-gnrh-antagonisten","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/nl\/product\/ganirelix-acetaat-cas-123246-29-7-gonadotropine-releasing-hormoon-gnrh-antagonisten\/","title":{"rendered":"Ganirelix-acetaat CAS 123246-29-7 Gonadotropine-releasing hormoon (GnRH)-antagonisten"},"content":{"rendered":"

Ganirelix-acetaat CAS 123246-29-7 Gonadotropine-releasing hormoon (GnRH)-antagonisten<\/strong><\/h2>\n

Productnaam: Ganirelix-acetaat
\nSynoniemen: Ac-DNal-DCpa-DPal-Ser-Tyr-DHar(Et2)-Leu-Har(Et2)-Pro-DAla -NH2;Ganirelixum;ganirelix-acetaat;GANIRELIX; Ganirelix-acetaat USP\/EP\/BP
\nCAS: 123246-29-7
\nMF: C80H113ClN18O13
\nMW: 1570.34
\nEINECS:
\nProductcategorie\u00ebn: hormonen
\nMol-bestand: 123246-29 -7.mol<\/p>\n

Ganirelix-acetaat is een synthetische decapeptideverbinding die lijkt op endogeen gonadotropine-releasing hormoon (GnRH) (ook bekend als lute\u00efniserend hormoon-releasing hormoon (LHRH)) en is een antagonist van GnRH die competitief de gonadotrope GnRH-receptor, waardoor de route wordt gemuteerd en een snelle en omkeerbare remming van de secretie van gonadotropine (lute\u00efniserend hormoon LH en follikelstimulerend hormoon FSH) wordt veroorzaakt. Ganirelix-acetaat remt de LH-secretie door de hypofyse significanter dan de FSH-secretie, waardoor de productie van geslachtshormonen wordt verminderd.<\/p>\n

Functie en toepassing van Ganirelix-acetaat CAS 123246-29-7<\/strong>
\nGanirelix-acetaat is een analoog van GnRH met substituties op residuen 1, 2, 3, 6, 8 en 10. Het is geen superagonist maar eerder een synthetisch decapeptide met hoge antagonistactiviteit en de eerste GnRH-antagonist die op de markt wordt gebracht. Het is goedgekeurd voor de onderdrukking van LH-pieken bij vrouwen die een vruchtbaarheidsbehandeling met hyperstimulatie van de eierstokken ondergaan; LH-pieken bevorderen normaal gesproken de ovulatie. Het doel van dit medicijn is om het aantal medicatiedagen dat nodig is om de LH-piek te onderdrukken aanzienlijk te verminderen, waardoor de eicellen in de eierstokken behouden blijven. Behandelingscycli voor in-vitrofertilisatie (IVF) werden in het verleden ge\u00efnitieerd door de toediening van leuprolide-acetaat om de voortijdige afgifte van LH te onderdrukken. Dit remt de eisprong, zodat de eieren beschikbaar blijven voor het ophalen door een vruchtbaarheidsspecialist. Voor dit doel wordt leuprolide-acetaat gewoonlijk gedurende maar liefst 26 dagen ge\u00efnjecteerd. Klinische studies hebben aangetoond dat ganirelix-acetaat de LH-toename in slechts 5 dagen behandeling kan stoppen, dat de onderdrukking van LH meer uitgesproken is dan die van FSH, en dat de kortere behandeltijd onaangename bijwerkingen, zoals opvliegers en hoofdpijn minimaliseert .<\/p>\n

Het wordt voornamelijk klinisch gebruikt in protocollen voor gecontroleerde ovari\u00eble stimulatie voor vrouwen die kunstmatige voortplantingstechnologie ondergaan om voortijdige lute\u00efniserend hormoonpieken te voorkomen en voor de behandeling van vruchtbaarheidsstoornissen die door deze oorzaak worden veroorzaakt Chemicalbook. Het medicijn heeft minder bijwerkingen, hoge zwangerschapspercentages en korte behandelingscycli, en heeft significante klinische voordelen in vergelijking met vergelijkbare medicijnen.<\/p>\n","protected":false},"excerpt":{"rendered":"

Productnaam: Ganirelix-acetaat
\nCAS: 123246-29-7
\nMF: C80H113ClN18O13
\nMW: 1570.34
\nProductcategorie\u00ebn: hormonen
\nMol-bestand: 123246-29-7.mol<\/p>\n","protected":false},"featured_media":2099,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[426,426,426],"product_tag":[1021],"class_list":{"0":"post-8703","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-urogenitale-peptide","9":"product_tag-ganirelix-acetate-cas-123246-29-7-gonadotropin-releasing-hormone-gnrh-antagonists-nl","10":"desktop-align-left","11":"tablet-align-left","12":"mobile-align-left","14":"first","15":"instock","16":"shipping-taxable","17":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product\/8703","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/comments?post=8703"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media\/2099"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media?parent=8703"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_brand?post=8703"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_cat?post=8703"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_tag?post=8703"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}