{"id":8725,"date":"2021-12-17T03:02:07","date_gmt":"2021-12-17T08:02:07","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/exenatide-acetaat-cas-141732-76-5-gebruikt-als-enteraal-hypoglykemisch-middel\/"},"modified":"2021-12-17T03:02:07","modified_gmt":"2021-12-17T08:02:07","slug":"exenatide-acetaat-cas-141732-76-5-gebruikt-als-enteraal-hypoglykemisch-middel","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/nl\/product\/exenatide-acetaat-cas-141732-76-5-gebruikt-als-enteraal-hypoglykemisch-middel\/","title":{"rendered":"Exenatide-acetaat CAS 141732-76-5 gebruikt als enteraal hypoglykemisch middel"},"content":{"rendered":"

Exenatide-acetaat CAS 141732-76-5 gebruikt als enteraal hypoglykemisch middel<\/strong><\/h2>\n

Productnaam: Exenatide-acetaat
\nSynoniemen: Exenatide;His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala -Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2};EXENATIDE-ACETAAT (EXENDIN -4);His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile- Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2;Exenatide-acetaat;EXENATIDE-ACETAAT;ENFUVIRTIDE-ACETAAT;Extendin-4
\nCAS : 141732-76-5
\nMF: C186H286N50O62S
\nMW: 4244.60796
\nEINECS: 1592732-453-0
\nProductcategorie\u00ebn: Agonist;Bases & gerelateerde reagentia;Peptide;Tussenproducten en fijne chemicali\u00ebn;Nucleotiden; Pharmaceuticals;GLP
\nMol File: 141732-76-5.mol<\/p>\n

De aminozuursequentie van Exenatide Acetate overlapt gedeeltelijk met humane GLP-1. Van exenatide-acetaat is aangetoond dat het in vitro bindt aan de bekende humane GLP-1-receptor en deze activeert. Dit betekent dat door het opnemen van cAMP (cyclisch adenosine monofosfaat) of andere intracellulaire signaalmechanismen, de glucose-afhankelijke insulinesynthese en insulinesecretie door pancreatische \u03b2-cellen in het lichaam worden verhoogd.<\/p>\n

Functie en toepassing van exenatideacetaat CAS 141732-76-5<\/strong>
\nToepassing van exenatide-acetaat veroorzaakt een toename van acinair cAMP zonder de afgifte van amylase te stimuleren. Als incretinemimeticum werkt exenatideacetaat als agonist van de glucagon-achtige peptide-1 (GLP-1) receptor. Als GLP-1, hoewel met langdurige activiteit, verhoogt exenatide-acetaat de postprandiale productie van insuline en onderdrukt het de secretie van glucagon. Om deze reden is exenatide-acetaat gebruikt als medicijn tegen diabetes II.<\/p>\n","protected":false},"excerpt":{"rendered":"

Productnaam: Exenatide-acetaat
\nCAS: 141732-76-5
\nMF: C186H286N50O62S
\nMW: 4244.60796
\nEINECS: 1592732-453-0
\nMol-bestand: 141732-76-5.mol<\/p>\n","protected":false},"featured_media":2204,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[],"product_tag":[999],"class_list":{"0":"post-8725","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_tag-exenatide-acetate-cas-141732-76-5-used-as-an-enteral-hypoglycemic-agent-nl","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product\/8725","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/comments?post=8725"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media\/2204"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media?parent=8725"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_brand?post=8725"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_cat?post=8725"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_tag?post=8725"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}