{"id":8899,"date":"2021-12-17T03:12:14","date_gmt":"2021-12-17T08:12:14","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/carbetocine-acetaat-cas-37025-55-1-preventie-van-zwakke-baarmoedercontracties-en-postpartumbloeding\/"},"modified":"2021-12-17T03:12:14","modified_gmt":"2021-12-17T08:12:14","slug":"carbetocine-acetaat-cas-37025-55-1-preventie-van-zwakke-baarmoedercontracties-en-postpartumbloeding","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/nl\/product\/carbetocine-acetaat-cas-37025-55-1-preventie-van-zwakke-baarmoedercontracties-en-postpartumbloeding\/","title":{"rendered":"Carbetocine-acetaat CAS 37025-55-1 Preventie van zwakke baarmoedercontracties en postpartumbloeding"},"content":{"rendered":"

Carbetocine-acetaat CAS 37025-55-1 Preventie van zwakke baarmoedercontracties en postpartumbloeding<\/strong><\/h2>\n

Productnaam: CARBETOCIN
\nSynoniemen: BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDEBOND TUSSEN BUTYRYL-4-YL EN CYS);BUTYRYL- TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2 TRIFLUOROACETAATZOUT;(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCINE-TRIFLUOROACETAATZOUT;(BUTYRYL1,TYR(ME)2)-OXYTOCINE ;(BUTYRYL1,TYR(ME)2)-OXYTOCINE-TRIFLUOROACETAATZOUT;CARBETOCINE;CARBETOCINE-TRIFLUOROACETAATZOUT;(2-O-METHYLTYROSINE)-DE-AMINO-1-CARBAOXYTOCINE
\nCAS: 37025-55-1
\nMF : C45H69N11O12S
\nMW: 988.17
\nEINECS: 253-312-6
\nProductcategorie\u00ebn: Overige API's;Peptide;Vasopressine- en oxytocinereceptor;Tussenproducten en fijnchemicali\u00ebn;Farmaceutica
\nMol-bestand: 37025-55- 1.mol<\/p>\n

Carbetocine is een synthetische langwerkende oxytocine 8-peptide-analoog met agonistische eigenschappen, met klinische en farmacologische eigenschappen die vergelijkbaar zijn met die van natuurlijk voorkomende oxytocine. Net als oxytocine bindt carbetocine zich aan de oxytocinereceptoren in de gladde spier van de baarmoeder, waardoor een ritmische samentrekking van de baarmoeder ontstaat die de frequentie verhoogt en de baarmoedertonus verhoogt bovenop de oorspronkelijke Chemicalbook-contractie. In de niet-zwangere toestand is het niveau van oxytocinereceptoren in de baarmoeder laag, neemt toe tijdens de zwangerschap en piekt bij de bevalling. Daarom heeft cabergoline geen effect op de niet-zwangere baarmoeder, maar heeft het een effectief samentrekkend effect van de baarmoeder op de zwangere baarmoeder en de baarmoeder die net is bevallen.<\/p>\n

CARBETOCIN Chemische eigenschappen van Carbetocin<\/strong>
\nalpha D – 69,0\u00b0 (c = 0,25 in 1M azijnzuur)
\nKookpunt 1477,9\u00b165,0 \u00b0C (voorspeld)
\ndichtheid 1,218\u00b10,06 g\/cm3 (voorspeld)
\nopslagtemp. -15\u00b0C
\nvorm poeder
\npka 13,07\u00b10,70(voorspeld)
\nkleur wit tot beige<\/p>\n

Functie en toepassing van carbetocine<\/strong>
\nVoor gebruik na electieve epidurale of lumbale anesthesie voor keizersnede bevalling om zwakke baarmoedercontracties en postpartumbloeding te voorkomen.
\nkeizersnede onder andere anesthesie voor spoedkeizersnede, klassieke keizersnede, epidurale of spinale anesthesie, of maternale aanwezigheid met significante hartziekte, voorgeschiedenis van hypertensie, bekende coagulopathie of lever, nier en endocriene ziekten (exclusief zwangerschapsdiabetes) Het gebruik van carbetocine is niet onderzocht. De toediening van carbetocine na vaginale bevalling is niet goed onderzocht en de dosis is niet vastgesteld.<\/p>\n","protected":false},"excerpt":{"rendered":"

Productnaam: CARBETOCIN
\nCAS: 37025-55-1
\nMF: C45H69N11O12S
\nMW: 988.17
\nEINECS: 253-312-6
\nMol-bestand: 37025-55-1.mol<\/p>\n","protected":false},"featured_media":2204,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[],"product_tag":[822],"class_list":{"0":"post-8899","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_tag-carbetocin-acetate-cas-37025-55-1-nl","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product\/8899","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/comments?post=8899"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media\/2204"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/media?parent=8899"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_brand?post=8899"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_cat?post=8899"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/nl\/wp-json\/wp\/v2\/product_tag?post=8899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}