Teduglutide/ ALX 0600 CAS 197922-42-2 For Lab Research

Teduglutide/ ALX 0600 CAS 197922-42-2 For Lab Research

Product Name: Teduglutide/ ALX 0600
Synonyms: ALX 0600;Gattex;Glucagon-like peptide II [2-glycine] (human);Teduglutide;ALX 0600 USP/EP/BP
CAS: 197922-42-2
MF: C164H252N44O55S
MW: 3752.08248
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Mol File: 197922-42-2.mol

Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology.

Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4.

Uses of Teduglutide/ ALX 0600 CAS 197922-42-2
Treatment of intestinal diseases characterized by chemical or surgical damage of the intestinal epithelium such as Short Bowel Syndrome (SBS) or damage to the intestinal epithelium due to disease (glucagon-like peptide-2 (GLP- 2) analog).

Application field of Teduglutide/ ALX 0600 CAS 197922-42-2
Teduglutide is a glucagon-like peptide-2 (GLP-2); regeneration, maintenance, and repair of the intestine.