{"id":7305,"date":"2021-12-16T07:21:44","date_gmt":"2021-12-16T12:21:44","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/carperitide-acetate-anp-1-28-human-cas-89213-87-6-para-tratamento-de-insuficiencia-cardiaca-congestiva\/"},"modified":"2021-12-16T07:21:44","modified_gmt":"2021-12-16T12:21:44","slug":"carperitide-acetate-anp-1-28-human-cas-89213-87-6-para-tratamento-de-insuficiencia-cardiaca-congestiva","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/pt-br\/product\/carperitide-acetate-anp-1-28-human-cas-89213-87-6-para-tratamento-de-insuficiencia-cardiaca-congestiva\/","title":{"rendered":"Carperitide Acetate \/ ANP 1-28, HUMAN CAS 89213-87-6 Para tratamento de insufici\u00eancia card\u00edaca congestiva"},"content":{"rendered":"

Carperitide Acetate \/ ANP 1-28, HUMAN CAS 89213-87-6 Para tratamento de insufici\u00eancia card\u00edaca congestiva<\/strong><\/h2>\n

Nome do produto: Acetato de carperitida \/ ANP 1-28, HUMANO
\n Sequ\u00eancia: H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg- Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH \uff0c (Ponte dissulfeto: Cys-Cys)
\n Sin\u00f4nimos: PEPT\u00cdDEO NATRIUR\u00c9TICO ATRIAL HUMANO; SER- LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER- PHE-ARG-TYR [SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY] PONTE DISULFIDE CYS7-CYS23.; Carperitide Acetate, carperitida; Atrial Natriuretic Peptide (1-28) (humano) (trifluoroacetate salt); Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe- Arg-Tyr-OH; Atrial natriureticpeptide-28 (huMan) (9CI); Atrial Natriuretic Factor (1-28) (huMan) \u03b1hANF, Carperitide
\n CAS: 89213-87-6
\n MF: C127H203N45O39S3
\n MW: 3080,44
\n EINECS: 686-482-9
\n Categorias de produtos: pept\u00eddeo
\n Arquivo Mol: 89213-87-6.mol <\/p>\n

Carperitide \u00e9 um polipept\u00eddeo de 28 amino\u00e1cidos com um secund\u00e1rio est\u00e1vel estrutura e \u00e9 um cir horm\u00f4nio culat\u00f3rio que atua como vasodilatador e diur\u00e9tico. Na pr\u00e1tica cl\u00ednica, a vasodilata\u00e7\u00e3o induzida pela carperitida como ingrediente principal deve-se \u00e0 liga\u00e7\u00e3o aos receptores ANP (polipept\u00eddeo natriur\u00e9tico atrial) no m\u00fasculo liso vascular, que \u00e9 alcan\u00e7ada pelo aumento da atividade da guanilato ciclase, sugerindo redu\u00e7\u00e3o da pr\u00e9 e p\u00f3s-carga card\u00edaca. <\/p>\n

Carperitide \u00e9 o pept\u00eddeo natriur\u00e9tico atrial humano \u03b1 (\u03b1-hANP) produzido por tecnologia recombinante. Foi introduzido no Jap\u00e3o como um tratamento para insufici\u00eancia card\u00edaca congestiva aguda (ICC). Em c\u00e3es com ICC, a carperitida reduziu significativamente a press\u00e3o diast\u00f3lica final do ventr\u00edculo esquerdo elevada e o \u00edndice de consumo de oxig\u00eanio do mioc\u00e1rdio (press\u00e3o arterial sist\u00f3lica x frequ\u00eancia card\u00edaca). Em um ensaio cl\u00ednico, a carperitida foi eficaz na melhora da hemodin\u00e2mica e dos sintomas em 60% dos pacientes com ICC aguda. A carperitida foi relatada como bem tolerada, sem efeitos adversos significativos clinicamente. Um efeito ben\u00e9fico na hemodin\u00e2mica foi relatado em pacientes com insufici\u00eancia card\u00edaca cr\u00f4nica. A carperitida tamb\u00e9m est\u00e1 em ensaios cl\u00ednicos para manuten\u00e7\u00e3o da press\u00e3o arterial durante opera\u00e7\u00f5es cir\u00fargicas. <\/p>\n

Aplica\u00e7\u00e3o<\/strong>
\n Tratamento da insufici\u00eancia card\u00edaca congestiva descompensada.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nome do produto: Carperitide Acetate \/ ANP 1-28, HUMAN
\n CAS: 89213-87-6
\n MF: C127H203N45O39S3
\n MW: 3080,44
\n EINECS: 686-482-9
\n Arquivo Mol: 89213-87-6.mol<\/p>\n","protected":false},"featured_media":2297,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[503],"product_tag":[2461,2483],"class_list":{"0":"post-7305","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptideo-do-sistema-cardiovascular","7":"product_tag-carperitide-acetate-anp-1-28-pt-br","8":"product_tag-human-cas-89213-87-6-for-treatment-of-congestive-heart-failure-pt-br","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/product\/7305","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/comments?post=7305"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/media\/2297"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/media?parent=7305"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/product_brand?post=7305"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/product_cat?post=7305"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/pt-br\/wp-json\/wp\/v2\/product_tag?post=7305"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}