{"id":7404,"date":"2021-12-16T07:58:28","date_gmt":"2021-12-16T12:58:28","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-pentru-cresterea-tensiunii-arteriale\/"},"modified":"2021-12-16T07:58:28","modified_gmt":"2021-12-16T12:58:28","slug":"angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-pentru-cresterea-tensiunii-arteriale","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/ro\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-pentru-cresterea-tensiunii-arteriale\/","title":{"rendered":"Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Pentru cre\u0219terea tensiunii arteriale"},"content":{"rendered":"

Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Pentru cre\u0219terea tensiunii arteriale<\/strong><\/h2>\n

Nume produs: ANGIOTENSIN II, UMAN
\nSecven\u021b\u0103: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
\nSinome: DRVYIHPF;[ILE5]-ANGIOTENSIN 2;HIPERTENSIUNE II UMAN;L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE;H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH;FLUORESCEIN-NHCS-NH-ASP-ARG- VAL-TYR-ILE-HIS-PRO-PHE-OH;ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O;ANGIOTENSIN II, UMAN
\nCAS: 4474-91-3<& >MF: C50H71N13O12
\nMW: 1046.2
\nEINECS: 2017-001-1
\nCategorii de produse: Angiotensin;peptide
\nMol File: 4474-91-3.mol<\/p>\n

Este cunoscut faptul c\u0103 \u021besuturile tumorale, inclusiv ganglionii limfatici metastatici, sunt compuse din vase nou \u00een cre\u0219tere, care nu au autoreglare a fluxului sanguin \u0219i sunt influen\u021bate doar secundar de vasele somatice care r\u0103spund. Angiotensin\u0103 II uman\u0103 (AT II). un vasopresor, a fost introdus \u00een Japonia pentru a \u00eembun\u0103t\u0103\u021bi eficacitatea chimioterapiei sistemice. La pacien\u021bii cu diferite cancere avansate, perfuzia iv de AT II pentru a ob\u021bine o tensiune arterial\u0103 medie de 1,5 ori fa\u021b\u0103 de valoarea ini\u021bial\u0103 (dar nu peste 150 mm Hg), urmat\u0103 de o injec\u021bie \u00een bolus de agen\u021bi citotoxici conven\u021bionali, cre\u0219te fluxul sanguin de 5-7 ori \u00een \u021besuturile tumorale. \u0219i, prin urmare, cre\u0219te livrarea medicamentului c\u0103tre \u021besutul \u021bint\u0103, rezult\u00e2nd efecte chimioterapeutice \u00eembun\u0103t\u0103\u021bite. Acest regim de chimioterapie cu hipertensiune arterial\u0103 indus\u0103 poate fi efectuat \u00een siguran\u021b\u0103, cu efecte secundare minime.<\/p>\n

Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Propriet\u0103\u021bi chimice<\/strong>
\nPunctul de fierbere 809,08\u00b0C (estimare aproximativ\u0103)<& >densitate 1,1257 (estimare aproximativ\u0103)
\nindice de refrac\u021bie 1,6700 (estimare)
\nRTECS BW2165000
\ntemp. A se p\u0103stra \u00eentr-un loc \u00eentunecat, Atmosfer\u0103 inert\u0103, A se p\u0103stra la congelator, sub -20\u00b0C
\nform\u0103 pulbere
\npka pK1: 10,37 (25\u00b0C)
\nculoare portocalie
\nsolubilitate \u00een ap\u0103 Solubil \u00een ap\u0103 (25 mg \/ml) \u0219i acid acetic 5% (1 mg\/ml).
\nInChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
\nCAS DataBase Reference 4474-91-3<\/p>\n

Func\u021bia \u0219i aplicarea angiotensinei II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3<\/strong>
\nAngiotensina II este o peptid\u0103 scurt\u0103 compus\u0103 din 8 aminoacizi, iar func\u021bia sa fiziologic\u0103 este \u00een principal de a cre\u0219te tensiunea arterial\u0103 prin constr\u00e2ngerea arterelor mici \u00een \u00eentregul corp. \u00cen plus, poate promova \u0219i secre\u021bia de aldosteron de c\u0103tre cortexul suprarenal, care ac\u021bioneaz\u0103 asupra tubilor renali pentru a p\u0103stra sodiul, apa \u0219i potasiul, provoc\u00e2nd astfel o cre\u0219tere a volumului \u0219i a tensiunii arteriale.<\/p>\n

Utiliz\u0103ri ale angiotensinei II\/ ANGIOTENSIN II, UMAN CAS 4474-91-3<\/strong>
\n1. Resuscitare cardiopulmonar\u0103 – nu este \u00eenc\u0103 o cerere aprobat\u0103
\n2. O peptid\u0103 implicat\u0103 \u00een reglarea tensiunii arteriale
\n3. Angiotensina II este un hormon peptidic cunoscut cel mai bine ca un vasoconstrictor cu roluri centrale \u00een hipertensiunea cronic\u0103, insuficien\u021ba cardiac\u0103 \u0219i accidentul vascular cerebral. Este o octapeptid\u0103 generat\u0103 de obicei prin \u00eendep\u0103rtarea a dou\u0103 reziduuri din angiotensina I de c\u0103tre enzima de conversie a angiotensinei (ACE). Angiotensina II este un ligand pentru cel pu\u021bin doi receptori diferi\u021bi, AT1 \u0219i AT2, fiecare evoc\u00e2nd c\u0103i de semnalizare \u0219i r\u0103spunsuri fiziologice distincte. Dezvoltarea antagoni\u015ftilor pentru subtipurile specifice de receptori de angiotensin\u0103 II reprezint\u0103 o alternativ\u0103 valoroas\u0103 la inhibitorii ECA.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nume produs: ANGIOTENSIN II, UMAN
\nCAS: 4474-91-3
\nMF: C50H71N13O12
\nMW: 1046.2
\nEINECS: 2017-001-1
\nMol File: 4474-91-3 .mol<\/p>\n","protected":false},"featured_media":2172,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[415],"product_tag":[2344,2366],"class_list":{"0":"post-7404","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-sange-si-peptide-vasculare","7":"product_tag-angiotensin-ii-angiotensin-ii-ro","8":"product_tag-human-cas-4474-91-3-for-blood-pressure-raising-ro","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product\/7404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/comments?post=7404"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/media\/2172"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/media?parent=7404"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_brand?post=7404"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_cat?post=7404"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_tag?post=7404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}