{"id":7833,"date":"2021-12-16T11:16:36","date_gmt":"2021-12-16T16:16:36","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/dsip-peptide-de-sommn-cas-62568-57-4-ajutor-pentru-un-somn-bine\/"},"modified":"2021-12-16T11:16:36","modified_gmt":"2021-12-16T16:16:36","slug":"dsip-peptide-de-sommn-cas-62568-57-4-ajutor-pentru-un-somn-bine","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/ro\/product\/dsip-peptide-de-sommn-cas-62568-57-4-ajutor-pentru-un-somn-bine\/","title":{"rendered":"DSIP\/ PEPTIDE DE SOMMN CAS 62568-57-4 Ajutor pentru un somn bine"},"content":{"rendered":"

Drotaverine Hidroklorida \/ Drotaverine Hcl CAS 985-12-6<\/strong><\/h2>\n

Nume produs: DSIP
\nSinonime: PEPTIDE INDUCERE A SOMMNULUI;WAGGDASGE;TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER- GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O;DELTA PEPTIDE INDUCERE A SOMMNULUI;DELTA PEPTIDE INDUCERE A SOMMNULUI 4H2O;DSIP
\nCAS: 62568-57-4
\nMF : C35H48N10O15
\nMW: 848,82
\nEINECS: 211-519-9
\nCategorii de produse: Peptide
\nFi\u0219ier Mol: 62568-57-4.mol<\/p>\n

Peptide inductoare de somn Delta, prescurtat DSIP, este o neuropeptid\u0103 care, atunci c\u00e2nd este infuzat\u0103 \u00een ventriculul mezodiencefalic al iepurilor primitori, induce activitate EEG ax \u0219i delta \u0219i activit\u0103\u021bi motorii reduse.<\/p>\n

DSIP CAS 985-12-6 Propriet\u0103\u021bi chimice<\/strong>
\nPunctul de fierbere 1522,7\u00b165,0 \u00b0C (Previzuit\u0103)
\ndensitate 1,458\u00b10,06 g\/cm3(Previzuit\u0103)
\ntemp. \u221220\u00b0C
\npka 3,18\u00b10,10(Previzual)
\nSolubilitate \u00een ap\u0103 Solubil \u00een ap\u0103 la 0,5mg\/ml
\nInChIKey ZRZROXNBKJAOKB-GFVHOAGBSA-N<\/p>\n

Func\u021bia DSIP<\/strong>
\nMulte roluri pentru DSIP au fost sugerate \u00een urma cercet\u0103rilor efectuate folosind analogi peptidici cu o stabilitate molecular\u0103 mai mare \u0219i prin m\u0103surarea r\u0103spunsului imunologic asem\u0103n\u0103tor DSIP (DSIP-LI) prin injectarea de antiser \u0219i anticorpi DSIP<\/p>\n

Roluri \u00een reglarea endocrin\u0103<\/strong>
\nScade bazal nivelul de corticotropin\u0103 \u0219i blocheaz\u0103 eliberarea acesteia.
\nStimuleaz\u0103 eliberarea hormonului luteinizant (LH).
\nStimuleaz\u0103 eliberarea de somatoliberin\u0103 \u0219i secre\u021bia de somatotrofin\u0103 \u0219i inhib\u0103 secre\u021bia de somatostatina.<\/p>\n

Structura \u0219i interac\u021biuni<\/strong>
\nDSIP este un amfifil peptid\u0103 cu greutate molecular\u0103 850 daltoni cu motivul aminoacizilor: N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C
\nA fost g\u0103sit\u0103 at\u00e2t \u00een form\u0103 liber\u0103, c\u00e2t \u0219i \u00een form\u0103 legat\u0103 \u00een hipotalamus, sistemul limbic \u0219i hipofizar, precum \u0219i diverse organe periferice, \u021besuturi \u0219i fluide corporale.[5] \u00cen hipofiz\u0103 se co-localizeaz\u0103 cu mul\u021bi mediatori peptidici \u0219i non-peptidici, cum ar fi peptida intermediar\u0103 asem\u0103n\u0103toare corticotropinei (CLIP), hormonul adrenocorticotrofic (ACTH), hormonul de stimulare a melanocitelor (MSH), hormonul de stimulare a tiroidei (TSH) \u0219i concentrarea melaninei. hormon (MCH). Este abundent \u00een celulele secretoare intestinale \u0219i \u00een pancreas unde se co-localizeaz\u0103 cu glucagonul.
\nIn vitro s-a descoperit c\u0103 are o stabilitate molecular\u0103 sc\u0103zut\u0103, cu un timp de \u00eenjum\u0103t\u0103\u021bire de numai 15 minute datorit\u0103 ac\u021biunii unui anumit Enzim\u0103 asem\u0103n\u0103toare aminopeptidazei. S-a sugerat c\u0103 \u00een organism se complexeaz\u0103 cu proteinele purt\u0103toare pentru a preveni degradarea sau c\u0103 exist\u0103 ca o component\u0103 a unei molecule precursoare mari, dar \u00eenc\u0103 nu a fost g\u0103sit\u0103 nicio structur\u0103 sau gen\u0103 pentru acest precursor.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nume produs: DSIP
\nCAS: 62568-57-4
\nMF: C35H48N10O15
\nMW: 848,82
\nEINECS: 211-519-9
\nMol File: 62568-57-4.mol<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[517],"product_tag":[1955],"class_list":{"0":"post-7833","1":"product","2":"type-product","3":"status-publish","5":"product_cat-alte-peptide","6":"product_tag-dsip-sleep-inducing-peptide-cas-62568-57-4-help-for-sleep-well-ro","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product\/7833","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/comments?post=7833"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/media?parent=7833"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_brand?post=7833"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_cat?post=7833"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_tag?post=7833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}