{"id":8155,"date":"2021-12-16T12:21:06","date_gmt":"2021-12-16T17:21:06","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/acetat-de-vapreotida-rc-160-cas-103222-11-3-tratament-pentru-sangerare-acuta-variceala-esofagiana\/"},"modified":"2021-12-16T12:21:06","modified_gmt":"2021-12-16T17:21:06","slug":"acetat-de-vapreotida-rc-160-cas-103222-11-3-tratament-pentru-sangerare-acuta-variceala-esofagiana","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/ro\/product\/acetat-de-vapreotida-rc-160-cas-103222-11-3-tratament-pentru-sangerare-acuta-variceala-esofagiana\/","title":{"rendered":"Acetat de vapreotid\u0103\/ RC 160 CAS 103222-11-3 Tratament pentru s\u00e2ngerare acut\u0103 variceal\u0103 esofagian\u0103"},"content":{"rendered":"

Acetat de vapreotid\u0103\/ RC 160 CAS 103222-11-3 Tratament pentru s\u00e2ngerare acut\u0103 variceal\u0103 esofagian\u0103<\/strong><\/h2>\n

Nume produs: VAPREOTIDE
\nSinome: D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 (punte disulfur\u0103 Cys2-Cys7);HD-Phe-Cys-Tyr-D -Trp-Lys-Val-Cys-Trp-NH2;D-Phe-Cys-Trp-D-Trp-Lys-Val-Cys-Trp-CONH2(disulfur\u0103 Cys2-Cys7);Vapreotid\u0103, RC-160;RC-160 ;VAPREOTIDE;D-PHE-CYS-TYR-D-TRP-LYS-VAL-CYS-TRP-NH2;FCYWKVCW-NH2
\nCAS: 103222-11-3
\nMF: C57H70N12O9S2
\nMW: 1131,37
\nEINECS:
\nCategorii de produse: Receptor de somatostatina
\nFi\u0219ier Mol: 103222-11-3.mol<\/p>\n

H3Pharma a achizi\u021bionat licen\u021ba de cercetare-dezvoltare \u0219i comerciale la nivel mondial pentru vaptan de la Debiopharm din Elve\u021bia. 2001 New England Journal of Medicine a raportat formula cu eliberare imediat\u0103, care a fost testat\u0103 clinic \u0219i dovedit\u0103 de Chemicalbook pentru utilizare timpurie \u00een tratamentul esofagiei acute. \u00cen 2004, subsidiara Debiopharm, specialistul canadian \u00een cancer \u0219i endocrinologie H3Pharma, a dezvoltat \u0219i fabricat un nou medicament. .<\/p>\n

Acetat de vapreotid\u0103\/ RC 160 CAS 103222-11-3 Propriet\u0103\u021bi chimice<\/strong>
\nPunctul de fierbere 1540,9\u00b165,0 \u00b0C (Previzual)
\ndensitate 1,40\u00b10,1 g\/cm3 (Previzual)
\ndepozitare temp. \u221220\u00b0C
\npka 9,90\u00b10,15(Previzual)<\/p>\n

Func\u021bia \u0219i aplicarea acetatului de vapreotid\u0103\/ RC 160 CAS 103222-11-3<\/strong>
\n1. Formularea cu eliberare imediat\u0103 a Sanvar, un analog al somatostatinei , este utilizat \u00een tratamentul s\u00e2nger\u0103rii variceale esofagiene acute (EVB).
\n2.Sanvar este utilizat \u00eenainte de interven\u021bia endoscopic\u0103 pentru a controla hemoragia \u0219i a preveni res\u00e2ngerarea \u00een timpul celor cinci zile critice de la debutul s\u00e2nger\u0103rii. EVB este o afec\u021biune care pune via\u021ba \u00een pericol \u0219i rata mortalit\u0103\u021bii este ridicat\u0103 (aproximativ 15% p\u00e2n\u0103 la 25%) \u00een primele \u0219ase s\u0103pt\u0103m\u00e2ni dup\u0103 hemoragie. EVB este cauza a aproximativ 70% din s\u00e2nger\u0103rile gastro-intestinale la pacien\u021bii care sufer\u0103 de ciroz\u0103 hepatic\u0103.
\n3.Sanvar (acetat de vapreotid\u0103) este un analog octapeptidic sintetic al hormonului somatostatin natural. Are propriet\u0103\u021bi farmacologice similare cu somatostatinei native, dar prezint\u0103 o durat\u0103 mai lung\u0103 de ac\u021biune. Este singurul analog al somatostatinei care a demonstrat beneficii semnificative statistic \u00een tratamentul precoce al EVB \u00een asociere cu terapia endoscopic\u0103, \u00eentr-un studiu clinic controlat cu placebo (Cal\u00e8s \u0219i colab. New England Journal of Medicine, 2001). Controlul s\u00e2nger\u0103rii cu supravie\u021buirea la cinci zile a fost realizat mai des cu Sanvar (p=0,021) dec\u00e2t cu placebo. Adi\u0163ional<\/p>\n","protected":false},"excerpt":{"rendered":"

Nume produs: VAPREOTIDE
\nCAS: 103222-11-3
\nMF: C57H70N12O9S2
\nMW: 1131,37
\nMol Fi\u0219ier: 103222-11-3.mol<\/p>\n","protected":false},"featured_media":2130,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[517],"product_tag":[1540],"class_list":{"0":"post-8155","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-alte-peptide","7":"product_tag-vapreotide-acetate-rc-160-cas-103222-11-3-treatment-for-acute-esophageal-variceal-bleeding-ro","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product\/8155","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/comments?post=8155"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/media\/2130"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/media?parent=8155"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_brand?post=8155"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_cat?post=8155"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_tag?post=8155"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}