{"id":8358,"date":"2021-12-16T13:24:47","date_gmt":"2021-12-16T18:24:47","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-supply-calcitonin-somon-cas-47931-85-1-pentru-osteoporoza\/"},"modified":"2021-12-16T13:24:47","modified_gmt":"2021-12-16T18:24:47","slug":"puya-supply-calcitonin-somon-cas-47931-85-1-pentru-osteoporoza","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/ro\/product\/puya-supply-calcitonin-somon-cas-47931-85-1-pentru-osteoporoza\/","title":{"rendered":"Puya Supply Calcitonin somon CAS 47931-85-1 pentru osteoporoz\u0103"},"content":{"rendered":"

Puya Supply Calcitonin somon CAS 47931-85-1 pentru osteoporoz\u0103<\/strong><\/h2>\n

Nume produs: Calcitonin somon
\nSinome: salmoncalcitonin-(i-32);salmoncalcitonini;tz-ct;Somon Calcitonin Acetat;Salcatonin;CALCITONIN SOMMON 250 UG;Calcitonina Acetat;Somon Calcium
\nSecven\u021ba: H-[ Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr -Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2\uff0c(punte disulfur\u0103: Cys1-Cys7)
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431,85
\n EINECS: 256-342-8
\nCategorii de produse: Deriva\u021bi de aminoacizi;Peptide;Calcitonina \u0219i receptorul CGRP
\nFi\u0219ier Mol: 47931-85-1.mol<\/p>\n

Calcitonina Somonul este un hormon polipeptidic secretat de glanda ultimobranhial\u0103 a somonului. Apar\u021bine familiei proteinelor asem\u0103n\u0103toare calcitoninei \u0219i poate fi utilizat\u0103 pentru a trata boala Paget a osului, osteoporoza postmenopauz\u0103 (oase fragile sau fragile) sau nivelurile ridicate de calciu \u00een s\u00e2nge (hipercalcemie). Se pare c\u0103 are ac\u021biuni \u00een esen\u021b\u0103 identice cu calcitoninele de origine mamifer\u0103, dar poten\u021ba sa per mg este mai mare \u0219i are o durat\u0103 mai lung\u0103 de ac\u021biune. Ac\u021bioneaz\u0103 \u00een principal prin inhibarea resorb\u021biei osoase osteoclastice, sc\u0103derea calciului seric \u0219i cre\u0219terea excre\u021biei renale de fosfat, calciu, sodiu, magneziu \u0219i potasiu prin sc\u0103derea reabsorb\u021biei tubulare.<\/p>\n

Calcitonina natural\u0103 este o peptid\u0103 bioactiv\u0103 secretat\u0103 de celulele paratiroide ale mamiferelor. sau branhiile posterioare ale vertebratelor \u0219i este principalul regulator al metabolismului calciului \u00een organismele vii. Acetatul de calcitonin\u0103 de somon este o 32-peptid\u0103 sintetic\u0103, iar \u00een cercetarea clinic\u0103, calcitonina de somon a fost utilizat\u0103 pe scar\u0103 larg\u0103 \u00een clinic\u0103 ca medicament preventiv \u0219i curativ pentru osteoporoz\u0103 \u0219i alte boli metabolice ale oaselor.<\/p>\n

Propriet\u0103\u021bi chimice ale calcitoninei somon CAS 47931-85-1<\/strong>
\nCalcitonina somon Propriet\u0103\u021bi chimice
\ndensitate 1,54\u00b10,1 g\/cm3(Predic\u021bie)
\ntemp. \u221220\u00b0C
\nsolubilitate 0,05 M acid acetic: 1 mg\/ml, limpede, incolor
\nform\u0103 pulbere
\nSolubilitate \u00een ap\u0103 Solubil \u00een ap\u0103 la 1mg\/ml
\nMerck 13,1642
\nInChIKey IYTKRMFJECGBRF -LXQLIYPUSA-N
\nCAS DataBase Reference 47931-85-1(CAS DataBase Reference)<\/p>\n

Func\u021bia \u0219i aplicarea calcitoninei somon CAS 47931-85-1<\/strong>
\n1. Somonul calcitonin poate fi utilizat pentru analiza receptorului de calcitonin\u0103\/cAMP pentru evaluarea prezen\u021bei receptorilor de calcitonin\u0103 exprima\u021bi de celulele TRAP+. Produsul poate fi, de asemenea, utilizat ca compus de testare pentru studierea \u0219i compararea impactului peptidei legate de gena calcitoninei (CGRP) \u0219i calcitonina de somon (sCT) pe bariera mucoasei gastrice la \u0219obolani expu\u0219i la frig + stres de re\u021binere (CRS). [sigma-aldrich]
\n2. Calcitonina, Somonul este un hormon de reglare a calciului secretat de celulele parafoliculare tiroidiene de mamifere \u0219i la speciile non-mamifere din glanda ultimobranhial\u0103. Calcitoninele sunt polipeptide cu un singur lan\u021b care con\u021bin 32 de resturi de aminoacizi, prezent\u00e2nd ac\u021biune hipocalcemic\u0103 \u0219i hipofosfatemic\u0103, cu structura aminoacizilor care difer\u0103 \u00eentre speciile de mamifere. Calcitonina de somon (salcatonina este analogul sintetic) prezint\u0103 o secven\u021b\u0103 semnificativ diferit\u0103 de cea a vertebratelor superioare, precum \u0219i o activitate mai puternic\u0103. Calcitonina de anghil\u0103 (Elcatonina) posed\u0103 un aminoacid similar cu cel al formei de somon, dar este mai stabil\u0103 dec\u00e2t calcitoninele naturale din cauza absen\u021bei pun\u021bilor disulfurice. [Biotehnologia Santa Cruz]
\n3. Prezint\u0103 ac\u021biune hipocalcemic\u0103 \u0219i hipofosfatemic\u0103, cu structur\u0103 de aminoacizi diferit\u0103 \u00een func\u021bie de speciile de mamifere. Calcitonina de somon (salcatonina este analogul sintetic) prezint\u0103 o secven\u021b\u0103 semnificativ diferit\u0103 de cea a vertebratelor superioare, precum \u0219i o activitate mai puternic\u0103. Scade calciul \u0219i fosfatul din s\u00e2nge datorit\u0103 inhib\u0103rii resorb\u021biei de c\u0103tre osteoblaste \u0219i osteocite. [alfa-aesar]
\n4. Hormonul peptidic de reglare a calciului eliberat de tiroida. Scade concentratia de calciu in sange si scade resorbtia osoasa de catre osteoclaste. Folosit pentru aplica\u021bii terapeutice \u00een osteoporoz\u0103. Secven\u021ba peptidei calcitoninei de somon difer\u0103 de cea a mamiferelor, dar este mai puternic\u0103. [Enzo Life Sciences, Inc.]<\/p>\n

Utiliz\u0103ri ale calcitoninei somonului CAS 47931-85-1<\/strong>
\nOsteoporoz\u0103;Hipercalcemie; boala Paget; Distrofia simpatic\u0103 reflex\u0103 (algodistrofie sau boala Sudeck)<\/p>\n","protected":false},"excerpt":{"rendered":"

Nume produs: Calcitonin somon
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431,85
\nEINECS: 256-342-8
\nMol File: 47931-85-1.mol<\/p>\n","protected":false},"featured_media":2109,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[489],"product_tag":[1320],"class_list":{"0":"post-8358","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptida-de-osteoporoza","7":"product_tag-puya-supply-calcitonin-salmon-cas-47931-85-1-for-osteoporosis-ro","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product\/8358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/comments?post=8358"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/media\/2109"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/media?parent=8358"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_brand?post=8358"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_cat?post=8358"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/ro\/wp-json\/wp\/v2\/product_tag?post=8358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}