{"id":8957,"date":"2021-12-17T03:40:01","date_gmt":"2021-12-17T08:40:01","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/linaclotida-cas-851199-59-2-pentru-tratarea-sindromului-de-colon-iritabil-constipat-ibs-c-si-a-constipatiei-cronice-idiopatice-cic\/"},"modified":"2021-12-17T03:40:01","modified_gmt":"2021-12-17T08:40:01","slug":"linaclotida-cas-851199-59-2-pentru-tratarea-sindromului-de-colon-iritabil-constipat-ibs-c-si-a-constipatiei-cronice-idiopatice-cic","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/ro\/product\/linaclotida-cas-851199-59-2-pentru-tratarea-sindromului-de-colon-iritabil-constipat-ibs-c-si-a-constipatiei-cronice-idiopatice-cic\/","title":{"rendered":"Linaclotida CAS 851199-59-2 Pentru tratarea sindromului de colon iritabil constipat (IBS-C) \u0219i a constipa\u021biei cronice idiopatice (CIC)"},"content":{"rendered":"<h2><strong>Linaclotida CAS 851199-59-2 Pentru tratarea sindromului de colon iritabil constipat (IBS-C) \u0219i a constipa\u021biei cronice idiopatice (CIC)<\/strong><\/h2>\n<p>Nume produs: Linaclotida<br \/>\nSinome: Linaclotida;Linaclotida;Acetat de linaelotida;Linaelotida;CY-14;Liclotida;Argpessin;L-tirozina, L-cisteinil-L-cisteinil-L-\u03b1-glutamil-L-tirosil -L-cisteinil-L-cisteinil-L-asparaginil-L-prolil-L-alanil-L-cisteinil-L-treonilglicil-L-cisteinil-, ciclic (1\u21926),(2\u219210),(5\u2192 13)-tris(disulfur\u0103)<br \/>\nCAS: 851199-59-2<br \/>\nMF: C59H79N15O21S6<br \/>\nMW: 1526,74<br \/>\nEINECS:<br \/>\nCategorii de produse: Inhibitori<br \/>\nFi\u0219ier Mol: 8591199 -2.mol<\/p>\n<p> <strong>Specifica\u021bia Linaclotidei<\/strong> <\/p>\n<table border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td> Con\u021binutul test\u0103rii<\/td>\n<td colspan=\"3\"> Specifica\u021bii<\/td>\n<\/tr>\n<tr>\n<td> Aspect<\/td>\n<td colspan=\"3\"> Pulbere cristalin\u0103 alb\u0103 sau aproape alb\u0103<\/td>\n<\/tr>\n<tr>\n<td> Identitate prin HPLC<\/td>\n<td colspan=\"3\"> Reac\u021bia este aceea\u0219i cu substan\u021ba de referin\u021b\u0103<\/td>\n<\/tr>\n<tr>\n<td> Compozi\u021bia aminoacizilor<\/td>\n<td colspan=\"3\"> \u00b120% din teoretic<\/td>\n<\/tr>\n<tr>\n<td> Puritate (HPLC)<\/td>\n<td colspan=\"3\"> \u2265 98,0%<\/td>\n<\/tr>\n<tr>\n<td> Substan\u021b\u0103 \u00eenrudit\u0103 (prin HPLC)<\/td>\n<td colspan=\"3\"> Total de impurit\u0103\u021bi (%)\u2264 2,0%<br \/>\nCea mai mare impuritate unic\u0103 (%)\u2264 1,0%<\/td>\n<\/tr>\n<tr>\n<td> Con\u021binut de acetat (prin HPLC)<\/td>\n<td colspan=\"3\"> \u226415%<\/td>\n<\/tr>\n<tr>\n<td> Con\u021binut de ap\u0103 (prin HPLC)<\/td>\n<td colspan=\"3\"> \u22645,0%<\/td>\n<\/tr>\n<tr>\n<td> Endotoxine bacteriene<\/td>\n<td colspan=\"3\"> \u22645UI\/mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p> <strong>Func\u021bia \u0219i aplicarea linaclotidei<\/strong><br \/>\nLinaclotida este un agonist peptidic al guanilat-ciclazei 2C.<\/p>\n<p>Acest compus reduce activarea neuronilor senzitivi ai colonului, reduc\u00e2nd durerea; \u0219i activeaz\u0103 neuronii motori ai colonului, ceea ce cre\u0219te contrac\u021bia mu\u0219chilor netezi \u0219i astfel promoveaz\u0103 mi\u0219c\u0103rile intestinale.<\/p>\n<p>A fost aprobat de FDA \u00een august 2012 pentru tratamentul constipa\u021biei cronice idiopatice \u0219i al sindromului de colon iritabil cu predominan\u021b\u0103 de constipa\u021bie (IBS-C). ) la adul\u021bi.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nume produs: Linaclotide<br \/>\nCAS: 851199-59-2<br \/>\nMF: C59H79N15O21S6<br \/>\nMW: 1526,74<br \/>\nEINECS:<br \/>\nCategorii de produse: Inhibitori<br \/>\nFi\u0219ier Mol: 851199-59-2. mol<\/p>\n","protected":false},"featured_media":2130,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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