{"id":7323,"date":"2021-12-16T07:22:36","date_gmt":"2021-12-16T12:22:36","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/carperitid-acetate-anp-1-28-human-cas-89213-87-6-for-behandling-av-kronisk-hjartsvikt\/"},"modified":"2021-12-16T07:22:36","modified_gmt":"2021-12-16T12:22:36","slug":"carperitid-acetate-anp-1-28-human-cas-89213-87-6-for-behandling-av-kronisk-hjartsvikt","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/sv\/product\/carperitid-acetate-anp-1-28-human-cas-89213-87-6-for-behandling-av-kronisk-hjartsvikt\/","title":{"rendered":"Carperitid Acetate\/ ANP 1-28, HUMAN CAS 89213-87-6 F\u00f6r behandling av kronisk hj\u00e4rtsvikt"},"content":{"rendered":"

Carperitid Acetate\/ ANP 1-28, HUMAN CAS 89213-87-6 F\u00f6r behandling av kronisk hj\u00e4rtsvikt<\/strong><\/h2>\n

Produktnamn: Carperitid Acetate\/ ANP 1-28, HUMAN
\nSekvens\uff1a H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg- Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH\uff0c(Disulfidbrygga: Cys-Cys)
\nSynonymer: NATRIURETISK PEPTID HUMAN;SER- LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER- PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDBRO CYS7-CYS23.;Carperitid Acetate, carperitida;Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetatsalt);ahANF, Carperitide; Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe- Arg-Tyr-OH;Atrial natriureticpeptide-28 (huMan) (9CI);Atrial Natriuretic Factor (1-28) (huMan) \u03b1hANF, Carperitid
\nCAS: 89213-87-6
\nMF: C127H203N45O39S3< MW: 3080.44
\nEINECS: 686-482-9
\nProduktkategorier: peptid
\nMol Fil: 89213-87-6.mol<\/p>\n

Carperitid \u00e4r en 28 aminosyror polypeptid med en stabil sekund\u00e4r struktur och \u00e4r en cir kulationshormon som verkar k\u00e4rlvidgande och urindrivande. I klinisk praxis beror vasodilatationen som induceras av karperitid som huvudingrediens p\u00e5 bindning till ANP (atrial natriuretic polypeptide)-receptorer i vaskul\u00e4r glatt muskulatur, vilket uppn\u00e5s genom att \u00f6ka aktiviteten av guanylatcyklas, vilket tyder p\u00e5 en minskning av hj\u00e4rtf\u00f6r- och efterbelastning. <\/p>\n

Carperitid \u00e4r den \u03b1-humana f\u00f6rmaksnatriuretiska peptiden (\u03b1-hANP) som produceras med rekombinant teknologi. Det introducerades i Japan som en behandling f\u00f6r akut hj\u00e4rtsvikt (CHF). Hos hundar med CHF minskade karperitid signifikant det f\u00f6rh\u00f6jda v\u00e4nstra ventrikul\u00e4ra slutdiastoliska trycket och indexet f\u00f6r myokardial syref\u00f6rbrukning (systoliskt blodtryck x hj\u00e4rtfrekvens). I en klinisk pr\u00f6vning var karperitid effektivt f\u00f6r att f\u00f6rb\u00e4ttra hemodynamiken och symtomen hos 60 % av patienterna med akut CHF. Karperitid rapporterades vara v\u00e4l tolererad utan n\u00e5gra signifikanta biverkningar kliniskt. En gynnsam effekt p\u00e5 hemodynamiken har rapporterats hos patienter med kronisk hj\u00e4rtsvikt. Carperitid \u00e4r ocks\u00e5 i kliniska pr\u00f6vningar f\u00f6r att uppr\u00e4tth\u00e5lla blodtrycket under kirurgiska operationer.<\/p>\n

Anv\u00e4ndning<\/strong>
\nBehandling av dekompenserad kronisk hj\u00e4rtsvikt.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnamn: Carperitid Acetate\/ ANP 1-28, HUMAN
\nCAS: 89213-87-6
\nMF: C127H203N45O39S3
\nMW: 3080.44
\nEINECS: 686-482-9:
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